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Results: 12

1.

Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs.

Pennacchietti S, Cazzanti M, Bertotti A, Rideout WM 3rd, Han M, Gyuris J, Perera T, Comoglio PM, Trusolino L, Michieli P.

Cancer Res. 2014 Nov 15;74(22):6598-609. doi: 10.1158/0008-5472.CAN-14-0761. Epub 2014 Sep 12.

PMID:
25217525
[PubMed - in process]
2.

Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy.

Zhou Y, Rideout WM 3rd, Bressel A, Yalavarthi S, Zi T, Potz D, Farlow S, Brodeur J, Monti A, Reddipalli S, Xiao Q, Bottega S, Feng B, Chiu MI, Bosenberg M, Heyer J.

PLoS One. 2014 Aug 27;9(8):e105886. doi: 10.1371/journal.pone.0105886. eCollection 2014.

PMID:
25162504
[PubMed - in process]
Free PMC Article
3.

Phase I ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma.

Patnaik A, Weiss GJ, Papadopoulos KP, Hofmeister CC, Tibes R, Tolcher A, Isaacs R, Jac J, Han M, Payumo FC, Cotreau MM, Ramanathan RK.

Br J Cancer. 2014 Jul 15;111(2):272-80. doi: 10.1038/bjc.2014.290. Epub 2014 Jun 5.

PMID:
24901237
[PubMed - indexed for MEDLINE]
4.

Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors.

Gandhi L, Bahleda R, Tolaney SM, Kwak EL, Cleary JM, Pandya SS, Hollebecque A, Abbas R, Ananthakrishnan R, Berkenblit A, Krygowski M, Liang Y, Turnbull KW, Shapiro GI, Soria JC.

J Clin Oncol. 2014 Jan 10;32(2):68-75. doi: 10.1200/JCO.2012.47.2787. Epub 2013 Dec 9.

PMID:
24323026
[PubMed - indexed for MEDLINE]
5.

Preclinical efficacy of the anti-hepatocyte growth factor antibody ficlatuzumab in a mouse brain orthotopic glioma model evaluated by bioluminescence, PET, and MRI.

Mittra ES, Fan-Minogue H, Lin FI, Karamchandani J, Sriram V, Han M, Gambhir SS.

Clin Cancer Res. 2013 Oct 15;19(20):5711-21. doi: 10.1158/1078-0432.CCR-12-1015. Epub 2013 Aug 27.

PMID:
23983258
[PubMed - indexed for MEDLINE]
Free Article
6.

KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations.

O'Hagan RC, Heyer J.

Genes Cancer. 2011 Mar;2(3):335-43. doi: 10.1177/1947601911408080.

PMID:
21779503
[PubMed]
Free PMC Article
7.

Development of second-generation VEGFR tyrosine kinase inhibitors: current status.

Bhargava P, Robinson MO.

Curr Oncol Rep. 2011 Apr;13(2):103-11. doi: 10.1007/s11912-011-0154-3. Review.

PMID:
21318618
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

GP369, an FGFR2-IIIb-specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling.

Bai A, Meetze K, Vo NY, Kollipara S, Mazsa EK, Winston WM, Weiler S, Poling LL, Chen T, Ismail NS, Jiang J, Lerner L, Gyuris J, Weng Z.

Cancer Res. 2010 Oct 1;70(19):7630-9. doi: 10.1158/0008-5472.CAN-10-1489. Epub 2010 Aug 13.

PMID:
20709759
[PubMed - indexed for MEDLINE]
Free Article
9.

Non-germline genetically engineered mouse models for translational cancer research.

Heyer J, Kwong LN, Lowe SW, Chin L.

Nat Rev Cancer. 2010 Jul;10(7):470-80. doi: 10.1038/nrc2877. Review.

PMID:
20574449
[PubMed - indexed for MEDLINE]
10.

Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas.

Zhou Y, Rideout WM 3rd, Zi T, Bressel A, Reddypalli S, Rancourt R, Woo JK, Horner JW, Chin L, Chiu MI, Bosenberg M, Jacks T, Clark SC, Depinho RA, Robinson MO, Heyer J.

Nat Biotechnol. 2010 Jan;28(1):71-8. doi: 10.1038/nbt.1595. Epub 2009 Dec 20.

PMID:
20023657
[PubMed - indexed for MEDLINE]
11.

VEGF kinase inhibitors: how do they cause hypertension?

Bhargava P.

Am J Physiol Regul Integr Comp Physiol. 2009 Jul;297(1):R1-5. doi: 10.1152/ajpregu.90502.2008. Epub 2009 May 13. Review.

PMID:
19439616
[PubMed - indexed for MEDLINE]
Free Article
12.

Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice.

Wu M, Jung L, Cooper AB, Fleet C, Chen L, Breault L, Clark K, Cai Z, Vincent S, Bottega S, Shen Q, Richardson A, Bosenburg M, Naber SP, DePinho RA, Kuperwasser C, Robinson MO.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7022-7. doi: 10.1073/pnas.0811785106. Epub 2009 Apr 15.

PMID:
19369208
[PubMed - indexed for MEDLINE]
Free PMC Article

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