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2002 2
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152 results

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RTS,S/AS01 vaccine (Mosquirix™): an overview.
Laurens MB. Laurens MB. Hum Vaccin Immunother. 2020 Mar 3;16(3):480-489. doi: 10.1080/21645515.2019.1669415. Epub 2019 Oct 22. Hum Vaccin Immunother. 2020. PMID: 31545128 Free PMC article.
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in terms of human morbidity and mortality, and therefore represents a major …
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected mosquitoes. Of the five species that …
Malaria therapeutics: are we close enough?
Tripathi H, Bhalerao P, Singh S, Arya H, Alotaibi BS, Rashid S, Hasan MR, Bhatt TK. Tripathi H, et al. Parasit Vectors. 2023 Apr 14;16(1):130. doi: 10.1186/s13071-023-05755-8. Parasit Vectors. 2023. PMID: 37060004 Free PMC article. Review.
A timely and accurate diagnosis is crucial for any disease, including malaria. The available diagnostic methods for malaria include microscopy, RDT, PCR, and non-invasive diagnosis. Recently, there have been several developments in detecting malaria, with imp …
A timely and accurate diagnosis is crucial for any disease, including malaria. The available diagnostic methods for malaria in …
Molecular methods for tracking residual Plasmodium falciparum transmission in a close-to-elimination setting in Zanzibar.
Grossenbacher B, Holzschuh A, Hofmann NE, Omar KA, Stuck L, Fakih BS, Ali A, Yukich J, Hetzel MW, Felger I. Grossenbacher B, et al. Malar J. 2020 Jan 29;19(1):50. doi: 10.1186/s12936-020-3127-x. Malar J. 2020. PMID: 31996210 Free PMC article.
BACKGROUND: Molecular detection of low-density Plasmodium falciparum infections is essential for surveillance studies conducted to inform malaria control strategies in close-to-elimination settings. Molecular monitoring of residual malaria infections u …
BACKGROUND: Molecular detection of low-density Plasmodium falciparum infections is essential for surveillance studies c …
Quantum dots: a new tool for anti-malarial drug assays.
Ku MJ, Dossin FM, Choi Y, Moraes CB, Ryu J, Song R, Freitas-Junior LH. Ku MJ, et al. Malar J. 2011 May 9;10:118. doi: 10.1186/1475-2875-10-118. Malar J. 2011. PMID: 21554712 Free PMC article.
BACKGROUND: Malaria infects over 300 million people every year and one of the major obstacles for the eradication of the disease is parasite's resistance to current chemotherapy, thus new drugs are urgently needed. Quantum dot (QD) is a fluorescent nanocrystal that …
BACKGROUND: Malaria infects over 300 million people every year and one of the major obstacles for the eradication of the disease is p …
Ultrasensitive Diagnostics for Low-Density Asymptomatic Plasmodium falciparum Infections in Low-Transmission Settings.
Zainabadi K. Zainabadi K. J Clin Microbiol. 2021 Mar 19;59(4):e01508-20. doi: 10.1128/JCM.01508-20. Print 2021 Mar 19. J Clin Microbiol. 2021. PMID: 33148707 Free PMC article. Review.
The emergence of multidrug-resistant Plasmodium falciparum malaria in Southeast Asia (SEA) has accelerated regional malaria elimination efforts. Most malaria in this and other low-transmission settings exists in asymptomatic individuals, which conventional diagno
The emergence of multidrug-resistant Plasmodium falciparum malaria in Southeast Asia (SEA) has accelerated regional malaria el …
The rapid manual ParaSight-F test. A new diagnostic tool for Plasmodium falciparum infection.
Shiff CJ, Premji Z, Minjas JN. Shiff CJ, et al. Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):646-8. doi: 10.1016/0035-9203(93)90273-s. Trans R Soc Trop Med Hyg. 1993. PMID: 8296363
A rapid manual test for Plasmodium falciparum, the ParaSight-F test, has been used on a series of patients in a holoendemic malaria area of coastal Tanzania. ...The remaining 4, although clear of peripheral parasitaemia, remained antigenaemic for 14 d. The test show …
A rapid manual test for Plasmodium falciparum, the ParaSight-F test, has been used on a series of patients in a holoendemic ma …
The Malaria System MicroApp: A New, Mobile Device-Based Tool for Malaria Diagnosis.
Oliveira AD, Prats C, Espasa M, Zarzuela Serrat F, Montañola Sales C, Silgado A, Codina DL, Arruda ME, I Prat JG, Albuquerque J. Oliveira AD, et al. JMIR Res Protoc. 2017 Apr 25;6(4):e70. doi: 10.2196/resprot.6758. JMIR Res Protoc. 2017. PMID: 28442456 Free PMC article.
As such, several groups have made developing news systems for the automated diagnosis of malaria a priority. OBJECTIVE: The objective of this study was to develop a new, automated, mobile device-based diagnostic system for malaria. The system uses Giemsa-stai …
As such, several groups have made developing news systems for the automated diagnosis of malaria a priority. OBJECTIVE: The objective …
Design and validation of multiplex polymerase chain reaction as a diagnostic tool for Plasmodium species.
Mahale P, Sinha S, Quadiri A, Sharma S, Gahtori R, Kumari P, Pande V, Singh H, Anvikar AR. Mahale P, et al. J Vector Borne Dis. 2023 Apr-Jun;60(2):200-206. doi: 10.4103/0972-9062.374038. J Vector Borne Dis. 2023. PMID: 37417170 Free article.
It contains one common reverse primer and three forward primers amplifying three targeted genes corresponding to P. falciparum, P. vivax, and Plasmodium genus. RESULTS: The sensitivity and specificity for mPCR were 94.06 and 95.74, respectively. ...The study has sho …
It contains one common reverse primer and three forward primers amplifying three targeted genes corresponding to P. falciparum, P. vi …
Performance Evaluation of Biozentech Malaria Scanner in Plasmodium knowlesi and P. falciparum as a New Diagnostic Tool.
Firdaus ER, Park JH, Muh F, Lee SK, Han JH, Lim CS, Na SH, Park WS, Park JH, Han ET. Firdaus ER, et al. Korean J Parasitol. 2021 Apr;59(2):113-119. doi: 10.3347/kjp.2021.59.2.113. Epub 2021 Apr 22. Korean J Parasitol. 2021. PMID: 33951766 Free PMC article.
A new computer malaria diagnostics tool called the malaria scanner was used to investigate living malaria parasites with easy sample preparation, fast and user-friendly. ...A strong correlation of measured parasitemia (r2=0.99, P<0.05) was observed between …
A new computer malaria diagnostics tool called the malaria scanner was used to investigate living malaria parasites wit …
A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery.
Almela MJ, Lozano S, Lelièvre J, Colmenarejo G, Coterón JM, Rodrigues J, Gonzalez C, Herreros E. Almela MJ, et al. PLoS One. 2015 Aug 28;10(8):e0135139. doi: 10.1371/journal.pone.0135139. eCollection 2015. PLoS One. 2015. PMID: 26317851 Free PMC article.
Recently, high-throughput screening (HTS) assays have been successfully applied to Plasmodium falciparum asexual stages to screen millions of compounds, with the identification of thousands of new active molecules, some of which are already in clinical phases …
Recently, high-throughput screening (HTS) assays have been successfully applied to Plasmodium falciparum asexual stages to scr …
152 results