[A hairy B cell lymphoproliferative disorder resembling hairy cell leukemia].
Rinsho Ketsueki. 2004.
PMID: 15168448
Japanese.
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BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes.
Mol Cancer. 2023 Aug 5;22(1):125. doi: 10.1186/s12943-023-01817-8.
Mol Cancer. 2023.
PMID: 37543582
Free PMC article.
Hairy cell leukemia (HCL) is a B-lymphoma induced by BRAF(V600E) mutation. ...Together, our study has uncovered concurrent mutations required for HCL ontogeny, revealed the B cell origin of hairy cells and investigated the molecular basis …
Hairy cell leukemia (HCL) is a B-lymphoma induced by BRAF(V600E) mutation. ...Together, our study has uncovered concurr …
Clonal dynamics in a composite chronic lymphocytic leukemia and hairy cell leukemia-variant.
Genes Chromosomes Cancer. 2021 Apr;60(4):287-292. doi: 10.1002/gcc.22925. Epub 2020 Dec 12.
Genes Chromosomes Cancer. 2021.
PMID: 33277788
Free PMC article.
Composite lymphoma is the rare simultaneous manifestation of two distinct lymphomas. Chronic lymphocytic leukemia (CLL) has a propensity for occurring in composite lymphomas, a phenomenon that remains to be elucidated. We applied cytogenetics, droplet digital polymerase ch …
Composite lymphoma is the rare simultaneous manifestation of two distinct lymphomas. Chronic lymphocytic leukemia (CLL) has a propens …
Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review.
Int J Clin Exp Pathol. 2011 Jan 5;4(2):183-9.
Int J Clin Exp Pathol. 2011.
PMID: 21326814
Free PMC article.
Review.
Hairy cell leukemia (HCL) is characterized by leukemic cells with abundant "hairy" cytoplasm, strong cytoplasmic positivity for tartrate-resistant acid phosphatase (TRAP), characteristic immunophenotype and sensitivity to treatment with purine nucleosi …
Hairy cell leukemia (HCL) is characterized by leukemic cells with abundant "hairy" cytoplasm, strong cytoplasmic …
[A hairy B cell lymphoproliferative disorder resembling hairy cell leukemia].
Rinsho Ketsueki. 2004 Apr;45(4):312-5.
Rinsho Ketsueki. 2004.
PMID: 15168448
Japanese.
This case report describes a hairy B cell lymphoproliferative disorder (HBLD) with clinical and hematological features resembling hairy cell leukemia. ...Atypical lymphocytes expressed CD5- CD10- CD11c+ CD19+ CD20+ CD …
This case report describes a hairy B cell lymphoproliferative disorder (HBLD) with clinical and hematolog …
Predominance of a distinct subtype of hairy cell leukemia in Japan.
Leukemia. 1993 Feb;7(2):181-6.
Leukemia. 1993.
PMID: 8426471
Forty Japanese patients with hairy cell leukemia (HCL) were reviewed. Nine cases were diagnosed as typical HCL, and two cases had the features of HCL variant (prolymphocytic variant). ...The cells showed weak expression of surface immunoglobulin G (IgG) with …
Forty Japanese patients with hairy cell leukemia (HCL) were reviewed. Nine cases were diagnosed as typical HCL, and two …
Polyclonal B-cell lymphocytosis with features resembling hairy cell leukemia-Japanese variant.
Blood. 1997 Mar 15;89(6):2008-14.
Blood. 1997.
PMID: 9058722
Free article.
Polyclonal B lymphocytosis was found in four patients having clinical and hematologic features resembling those of hairy cell leukemia (HCL). All four patients were women between 37 and 67 years of age. ...Although these findings were similar to those …
Polyclonal B lymphocytosis was found in four patients having clinical and hematologic features resembling those of hairy ce …
Immunohistochemical detection of hairy cell leukemia in paraffin sections using a highly effective CD103 rabbit monoclonal antibody.
Am J Clin Pathol. 2013 Feb;139(2):220-30. doi: 10.1309/AJCPHW7RULIZT2GB.
Am J Clin Pathol. 2013.
PMID: 23355207
Detection of the integrin subunit CD103 is a useful diagnostic tool in the diagnosis of hairy cell leukemia (HCL). Currently, flow cytometric analysis (FC) and frozen section immunohistochemistry (IHC) represent the only available methods of detection. This s …
Detection of the integrin subunit CD103 is a useful diagnostic tool in the diagnosis of hairy cell leukemia (HCL). Curr …
CD27-positive hairy cell leukemia-Japanese variant.
Virchows Arch. 2016 Mar;468(3):375-9. doi: 10.1007/s00428-015-1881-x. Epub 2016 Feb 11.
Virchows Arch. 2016.
PMID: 26868143
We report a very rare case of a 45-year-old Japanese male patient with hairy cell leukemia-Japanese variant (HCL-JV) expressing CD27. The patient showed a high number of abnormal peripheral lymphocytes, thrombocytopenia, and severe splenomegaly but no lymphad …
We report a very rare case of a 45-year-old Japanese male patient with hairy cell leukemia-Japanese variant (HCL-JV) ex …
A case of hairy cell leukemia with CCND1-IGH@ translocation: indolent non-nodal mantle cell lymphoma revisited.
Am J Surg Pathol. 2011 Jul;35(7):1080-4. doi: 10.1097/PAS.0b013e31821ddaec.
Am J Surg Pathol. 2011.
PMID: 21677543
CCND1-IGH@ translocation is considered pathognomonic of mantle cell lymphoma (MCL), as this distinct chromosomal abnormality has not been reported in any other subtypes of mature B-cell lymphoma. ...Herein, we report a patient with clinical and cytogenetic fe …
CCND1-IGH@ translocation is considered pathognomonic of mantle cell lymphoma (MCL), as this distinct chromosomal abnormality has not …
The role of interleukin-6 in a patient with polyclonal hairy B-cell lymphoproliferative disorder: a case report.
Lab Hematol. 2007;13(4):124-7. doi: 10.1532/LH96.07015.
Lab Hematol. 2007.
PMID: 18192143
An 80-year-old female patient showed persistent lymphocytosis morphologically resembling the Japanese variant of hairy cell leukemia (HCL). However, flow cytometric analysis determined that these lymphocytes were of polyclonal B-cell orig …
An 80-year-old female patient showed persistent lymphocytosis morphologically resembling the Japanese variant of hairy cell …
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