A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor

J Med Chem. 1998 Dec 17;41(26):5148-9. doi: 10.1021/jm9803525.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Benzofurans / chemical synthesis*
  • Benzofurans / metabolism
  • Benzofurans / pharmacology
  • Binding, Competitive
  • Discrimination Learning / drug effects
  • Humans
  • In Vitro Techniques
  • Ligands
  • Prefrontal Cortex / drug effects
  • Prefrontal Cortex / metabolism
  • Propylamines / chemical synthesis*
  • Propylamines / metabolism
  • Propylamines / pharmacology
  • Radioligand Assay
  • Rats
  • Receptor, Serotonin, 5-HT2A
  • Receptor, Serotonin, 5-HT2B
  • Receptor, Serotonin, 5-HT2C
  • Receptors, Serotonin / drug effects*
  • Receptors, Serotonin / metabolism
  • Serotonin Agents / chemical synthesis*
  • Serotonin Agents / chemistry
  • Serotonin Agents / pharmacology

Substances

  • 4-(2-aminopropyl)-8-bromobenzofurano(6,5-a)furan
  • Benzofurans
  • Ligands
  • Propylamines
  • Receptor, Serotonin, 5-HT2A
  • Receptor, Serotonin, 5-HT2B
  • Receptor, Serotonin, 5-HT2C
  • Receptors, Serotonin
  • Serotonin Agents