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The following term was not found in PubMed: 6-phenyl-1H-pyrazolo
Unknown field was ignored: [3,4-b]
Page 1
Identification of Novel Thiazolo[5,4-b]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors.
Xia L, Zhang Y, Zhang J, Lin S, Zhang K, Tian H, Dong Y, Xu H. Xia L, et al. Molecules. 2020 Oct 12;25(20):4630. doi: 10.3390/molecules25204630. Molecules. 2020. PMID: 33053730 Free PMC article.
A series of novel 2-pyridyl, 4-morpholinyl substituted thiazolo[5,4-b]pyridine analogues have been designed and synthesized in this paper. These thiazolo[5,4-b]pyridines were efficiently prepared in seven steps from commercially available substances in moderate to g …
A series of novel 2-pyridyl, 4-morpholinyl substituted thiazolo[5,4-b]pyridine analogues have been designed and synthesized in this p …
4,6-Dimethyl-2-[(4-phenylpiperidin-1-yl)methyl]isothiazolo[5,4-b]pyridin-3(2H)-one and 4,6-dimethyl-2-[(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)methyl]isothiazolo[5,4-b]pyridin-3(2H)-one.
Karczmarzyk Z, Malinka W. Karczmarzyk Z, et al. Acta Crystallogr C. 2007 Aug;63(Pt 8):o477-80. doi: 10.1107/S0108270107031071. Epub 2007 Jul 26. Acta Crystallogr C. 2007. PMID: 17675700
The molecular packing in (II) is influenced by pi-pi interactions of the isothiazolopyridine systems, with a shortest centroid-to-centroid separation of 3.5843 (11) A between pyridine rings. In the crystal structure of (III), the molecules are linked by C-H...O hydrogen bo …
The molecular packing in (II) is influenced by pi-pi interactions of the isothiazolopyridine systems, with a shortest centroid-to-centroid s …
Affinity of Antifungal Isoxazolo[3,4-b]pyridine-3(1H)-Ones to Phospholipids in Immobilized Artificial Membrane (IAM) Chromatography.
Ciura K, Fedorowicz J, Žuvela P, Lovrić M, Kapica H, Baranowski P, Sawicki W, Wong MW, Sączewski J. Ciura K, et al. Molecules. 2020 Oct 20;25(20):4835. doi: 10.3390/molecules25204835. Molecules. 2020. PMID: 33092252 Free PMC article.
The present study is a continuation of our research focused on physiochemical characterization of biologically active derivatives of isoxazolo[3,4-b]pyridine-3(1H)-ones. The main goal of this study was to assess the affinity of isoxazolones to phospholipids using IAM chrom …
The present study is a continuation of our research focused on physiochemical characterization of biologically active derivatives of isoxazo …
Pyridine.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risks Hum. 2000;77:503-28. IARC Monogr Eval Carcinog Risks Hum. 2000. PMID: 11100414 Free PMC article. Review. No abstract available.
One-pot combinatorial synthesis of 4-aryl-1H-thiopyrano[3,4-b]pyridine-5-one derivatives.
Yao CS, Wang CH, Jiang B, Tu SJ. Yao CS, et al. J Comb Chem. 2010 Jul 12;12(4):472-5. doi: 10.1021/cc100017f. J Comb Chem. 2010. PMID: 20443618
A simple and efficient method for the combinatorial synthesis of highly substituted thiopyrano[3,4-b]pyridin-5(4H)-one, thiopyrano[3,4-b]quinoline-4,6(3H,5H)-dione, dithiopyrano[3,4-b:4',3'-e]pyridine-4,6(1H,3H)-dione, and pyrazolo[3,4-b]thiopyrano[4,3-e]pyridin …
A simple and efficient method for the combinatorial synthesis of highly substituted thiopyrano[3,4-b]pyridin-5(4H)-one, thiopyrano[3, …
Synthesis of pyrazolo[3,4-b]pyridines under microwave irradiation in multi-component reactions and their antitumor and antimicrobial activities - Part 1.
El-borai MA, Rizk HF, Abd-Aal MF, El-Deeb IY. El-borai MA, et al. Eur J Med Chem. 2012 Feb;48:92-6. doi: 10.1016/j.ejmech.2011.11.038. Epub 2011 Dec 1. Eur J Med Chem. 2012. PMID: 22178093
An efficient one-pot synthesis in multi-component system (MRCs) for the preparation of pyrazolo[3,4-b]pyridine derivatives from the reaction of 5-amino-1-phenyl-3-(pyridin-3-yl)-1H-pyrazole with 4-anisaldehyde and p-substituted beta-ketonitriles or with pyruvic acid …
An efficient one-pot synthesis in multi-component system (MRCs) for the preparation of pyrazolo[3,4-b]pyridine derivatives from the r …
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3-b]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase.
Grisez T, Ravi NP, Froeyen M, Schols D, Van Meervelt L, De Jonghe S, Dehaen W. Grisez T, et al. Molecules. 2024 Feb 22;29(5):954. doi: 10.3390/molecules29050954. Molecules. 2024. PMID: 38474466 Free PMC article.
Disubstituted isothiazolo[4,3-b]pyridines are known inhibitors of cyclin G-associated kinase. Since 3-substituted-7-aryl-isothiazolo[4,3-b]pyridines remain elusive, a strategy was established to prepare this chemotype, starting from 2,4-dichloro-3-nitropyridine. ... …
Disubstituted isothiazolo[4,3-b]pyridines are known inhibitors of cyclin G-associated kinase. Since 3-substituted-7-aryl-isothiazolo[ …
Synthesis of novel 1,2,3-triazole tagged pyrazolo[3,4-b]pyridine derivatives and their cytotoxic activity.
Kurumurthy C, Veeraswamy B, Sambasiva Rao P, Santhosh Kumar G, Shanthan Rao P, Loka Reddy V, Venkateswara Rao J, Narsaiah B. Kurumurthy C, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):746-9. doi: 10.1016/j.bmcl.2013.12.107. Epub 2014 Jan 3. Bioorg Med Chem Lett. 2014. PMID: 24424132
A series of novel 1,2,3-triazole tagged pyrazolo[3,4-b]pyridine derivatives 3 and 4 were prepared respectively starting from 6-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine 1 via selective N-propargylation, followed by reaction with diverse substitute …
A series of novel 1,2,3-triazole tagged pyrazolo[3,4-b]pyridine derivatives 3 and 4 were prepared respectively starting from 6-phenyl …
6-Tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide analogues: synthesis, characterization, MO calculation, and antibacterial activity.
Doshi H, Thakkar S, Khirsariya P, Thakur MC, Ray A. Doshi H, et al. Appl Biochem Biotechnol. 2015 Feb;175(3):1700-9. doi: 10.1007/s12010-014-1399-8. Epub 2014 Nov 26. Appl Biochem Biotechnol. 2015. PMID: 25422060
A series of 6-tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide analogues are synthesized by conventional techniques and characterized by elemental analysis, IR, MS, (1)H, and (13)C NMR. ...
A series of 6-tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide analogues are synthesized by conventional techniques and ch …
Lipophilicity Determination of Antifungal Isoxazolo[3,4-b]pyridin-3(1H)-ones and Their N1-Substituted Derivatives with Chromatographic and Computational Methods.
Ciura K, Fedorowicz J, Andrić F, Žuvela P, Greber KE, Baranowski P, Kawczak P, Nowakowska J, Bączek T, Sączewski J. Ciura K, et al. Molecules. 2019 Nov 26;24(23):4311. doi: 10.3390/molecules24234311. Molecules. 2019. PMID: 31779124 Free PMC article.
This study was aimed to evaluate the lipophilicity of isoxazolo[3,4-b]pyridine-3(1H)-ones and their N1-substituted derivatives, which demonstrated pronounced antifungal activities. ...
This study was aimed to evaluate the lipophilicity of isoxazolo[3,4-b]pyridine-3(1H)-ones and their N1-substituted derivatives, which …
330,334 results
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