Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 1
1993 1
1994 1
1997 1
1998 1
1999 2
2001 1
2002 1
2003 1
2004 1
2007 2
2008 3
2009 1
2010 3
2011 4
2012 3
2014 3
2015 4
2016 1
2017 5
2018 7
2019 7
2020 3
2021 2
2022 2
2023 4
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

59 results

Results by year

Filters applied: . Clear all
Page 1
The flavonoid 6-hydroxyflavone prevention of cisplatin-induced nephrotoxicity.
Din ZU, Farooq SU, Shahid M, Alghamdi O, Al-Hamoudi N, Vohra F, Abduljabbar T. Din ZU, et al. Histol Histopathol. 2020 Oct;35(10):1197-1209. doi: 10.14670/HH-18-251. Epub 2020 Sep 10. Histol Histopathol. 2020. PMID: 32909617
In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model of nephrotoxicity. ...Moreover, 6-hydroxyflavone also reduced the cisplatin-induced lipid peroxidation and corrected the renal …
In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model o …
6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells.
Wang X, Wang Z, Sidhu PS, Desai UR, Zhou Q. Wang X, et al. PLoS One. 2015 Mar 19;10(3):e0116409. doi: 10.1371/journal.pone.0116409. eCollection 2015. PLoS One. 2015. PMID: 25790236 Free PMC article.
The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypetin, apigenin and myricetin were investigated on rat mesangial cells with lipopolysaccharide (LPS) as the inflammatory stimuli. 6-H …
The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypet …
Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells.
Lai CH, Wu YW, Yeh SD, Lin YH, Tsai YH. Lai CH, et al. Evid Based Complement Alternat Med. 2014;2014:924560. doi: 10.1155/2014/924560. Epub 2014 Mar 26. Evid Based Complement Alternat Med. 2014. PMID: 24795772 Free PMC article.
This study investigates the effects of various hydroxyflavones on osteoblast differentiation in MC3T3-E1 cells. The results showed that 6-hydroxyflavone (6-OH-F) and 7-hydroxyflavone (7-OH-F) stimulated ALP activity. ...
This study investigates the effects of various hydroxyflavones on osteoblast differentiation in MC3T3-E1 cells. The results showed that 6 …
Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone.
Flores-Flores A, Estrada-Soto S, Millán-Pacheco C, Bazán-Perkins B, Villalobos-Molina R, Moreno-Fierros L, Hernández-Pando R, García-Jiménez S, Rivera-Leyva JC. Flores-Flores A, et al. Drug Dev Res. 2019 Mar;80(2):218-229. doi: 10.1002/ddr.21484. Epub 2018 Nov 5. Drug Dev Res. 2019. PMID: 30394554
Previously, we described tracheal rat rings relaxation by several flavonoids, being 6-hydroxyflavone (6-HOF) the most active derivative of the series. ...
Previously, we described tracheal rat rings relaxation by several flavonoids, being 6-hydroxyflavone (6-HOF) the most active d …
Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses.
Das S, Karn A, Sarmah R, Rohman MA, Koley S, Ghosh P, Roy AS. Das S, et al. J Photochem Photobiol B. 2018 Jan;178:40-52. doi: 10.1016/j.jphotobiol.2017.10.021. Epub 2017 Oct 28. J Photochem Photobiol B. 2018. PMID: 29102848
Both 6-hydroxyflavone and chrysin can quench the intrinsic fluorescence intensity of BHb via static quenching mechanism. ...The binding distances from donor BHb to the acceptor ligands (6-hydroxyflavone and chrysin) were estimated using the Foster's th …
Both 6-hydroxyflavone and chrysin can quench the intrinsic fluorescence intensity of BHb via static quenching mechanism. ...Th …
The flavonoid derivative 4'-nitro-6-hydroxyflavone suppresses the activity of HNF4alpha and stimulates the degradation of HNF4alpha protein through the activation of AMPK.
Inoue J, Ikeda S, Kanayama T, Sato R. Inoue J, et al. Biosci Biotechnol Biochem. 2017 Aug;81(8):1548-1552. doi: 10.1080/09168451.2017.1325316. Epub 2017 May 5. Biosci Biotechnol Biochem. 2017. PMID: 28475422
Using this system, we show here that the flavonoid derivative 4'-nitro-6-hydroxyflavone (NOHF) suppresses MTP promoter activity. Treatment with NOHF caused a decrease in the expression of the HNF4alpha target gene. ...
Using this system, we show here that the flavonoid derivative 4'-nitro-6-hydroxyflavone (NOHF) suppresses MTP promoter activit …
An insight into the binding of 6-hydroxyflavone with hen egg white lysozyme: a combined approach of multi-spectroscopic and computational studies.
Das S, Santra S, Rohman MA, Ray M, Jana M, Singha Roy A. Das S, et al. J Biomol Struct Dyn. 2019 Sep;37(15):4019-4034. doi: 10.1080/07391102.2018.1535451. Epub 2018 Dec 10. J Biomol Struct Dyn. 2019. PMID: 30314416
The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and computational methods. ...
The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and c …
6-Acetamidoflavone obtained by microbiological and chemical methods and its antioxidant activity.
Stompor M. Stompor M. J Biotechnol. 2016 Nov 10;237:25-34. doi: 10.1016/j.jbiotec.2016.09.006. Epub 2016 Sep 13. J Biotechnol. 2016. PMID: 27637313
The antioxidant activity of flavone, and its C-6 substituted derivatives: 6-aminoflavone (1), 6-hydroxyflavone and isolated metabolite 6-acetamidoflavone (2) has been examined using the ABTS and DPPH methods....
The antioxidant activity of flavone, and its C-6 substituted derivatives: 6-aminoflavone (1), 6-hydroxyflavone and isolated me …
Biotransformations of Flavones and an Isoflavone (Daidzein) in Cultures of Entomopathogenic Filamentous Fungi.
Dymarska M, Janeczko T, Kostrzewa-Susłow E. Dymarska M, et al. Molecules. 2018 Jun 5;23(6):1356. doi: 10.3390/molecules23061356. Molecules. 2018. PMID: 29874813 Free PMC article.
Their catalytic capacity to carry out biotransformations of flavones-unsubstituted, with hydroxy- and amino-substituents as well as a hydroxylated isoflavone-was investigated. Biotransformations of flavone, 5-hydroxyflavone, 6-hydroxyflavone, 7-hydroxyflavone, and d …
Their catalytic capacity to carry out biotransformations of flavones-unsubstituted, with hydroxy- and amino-substituents as well as a hydrox …
3-Hydroxyflavone enhances the toxicity of ZnO nanoparticles in vitro.
Luo Y, Wu C, Liu L, Gong Y, Peng S, Xie Y, Cao Y. Luo Y, et al. J Appl Toxicol. 2018 Sep;38(9):1206-1214. doi: 10.1002/jat.3633. Epub 2018 Apr 25. J Appl Toxicol. 2018. PMID: 29691881
Surprisingly, H3 markedly decreased the initial concentration of ZnO NPs required to induce cytotoxicity to Caco-2, HepG2, THP-1 and human umbilical vein endothelial cells, which suggested that H3 could promote the toxicity of ZnO NPs to both cancerous and normal cells. For compa …
Surprisingly, H3 markedly decreased the initial concentration of ZnO NPs required to induce cytotoxicity to Caco-2, HepG2, THP-1 and human u …
59 results