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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 21
1785 43
1795 13
1799 23
1800 1
1801 171
1802 4
1803 1
1804 1
1806 17
1810 51
1811 2
1814 1
1815 30
1816 6
1819 2
1821 17
1825 17
1826 10
1827 26
1828 2
1829 95
1832 25
1833 5
1835 12
1836 2
1837 38
1838 100
1839 7
1840 49
1841 30
1842 120
1843 487
1844 81
1845 148
1846 245
1847 142
1848 78
1849 158
1850 556
1851 138
1852 127
1853 163
1854 68
1855 79
1856 168
1857 241
1858 129
1859 298
1860 243
1861 260
1862 82
1863 48
1864 83
1865 150
1866 211
1867 213
1868 103
1869 147
1870 121
1871 418
1872 249
1873 174
1874 210
1875 160
1876 296
1877 151
1878 195
1879 218
1880 236
1881 275
1882 236
1883 195
1884 187
1885 981
1886 202
1887 277
1888 314
1889 686
1890 295
1891 351
1892 261
1893 233
1894 197
1895 204
1896 267
1897 548
1898 245
1899 215
1900 161
1901 235
1902 174
1903 174
1904 311
1905 242
1906 226
1907 196
1908 438
1909 164
1910 190
1911 195
1912 270
1913 1413
1914 295
1915 256
1916 599
1917 224
1918 245
1919 294
1920 359
1921 297
1922 378
1923 318
1924 429
1925 366
1926 373
1927 461
1928 477
1929 460
1930 608
1931 598
1932 513
1933 481
1934 533
1935 483
1936 452
1937 482
1938 505
1939 482
1940 442
1941 430
1942 476
1943 384
1944 410
1945 883
1946 3109
1947 6555
1948 5758
1949 4847
1950 8507
1951 11502
1952 9363
1953 9243
1954 10236
1955 9790
1956 9458
1957 9976
1958 9807
1959 5203
1960 2513
1961 4266
1962 3022
1963 4297
1964 4565
1965 13331
1966 17638
1967 19321
1968 19864
1969 20046
1970 20534
1971 21603
1972 22354
1973 21384
1974 22503
1975 33163
1976 35092
1977 36074
1978 37010
1979 38252
1980 41179
1981 42831
1982 45962
1983 51056
1984 55460
1985 58841
1986 61679
1987 64615
1988 67276
1989 77184
1990 81079
1991 83685
1992 87840
1993 88751
1994 91788
1995 97220
1996 101314
1997 102698
1998 104961
1999 110646
2000 119994
2001 121571
2002 126162
2003 134372
2004 146667
2005 161948
2006 174828
2007 181218
2008 191956
2009 203961
2010 222472
2011 250765
2012 256800
2013 269509
2014 285702
2015 307025
2016 317241
2017 306612
2018 324239
2019 336625
2020 391344
2021 424951
2022 412392
2023 382506
2024 138601
2025 1

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The following terms were not found in PubMed: 1-adamantylcarbamoylamino, -N-phenethyl-hexanamide
Page 1
Historical overview of the interleukin-6 family cytokine.
Kang S, Narazaki M, Metwally H, Kishimoto T. Kang S, et al. J Exp Med. 2020 May 4;217(5):e20190347. doi: 10.1084/jem.20190347. J Exp Med. 2020. PMID: 32267936 Free PMC article. Review.
Later, IL-6 was revealed to have various functions that overlap with other IL-6 family cytokines and use the common IL-6 signal transducer gp130. IL-6 stimulates cells through multiple pathways, using both membrane and soluble IL-6 receptors. .. …
Later, IL-6 was revealed to have various functions that overlap with other IL-6 family cytokines and use the common IL-6 …
IL-6 pathway in the liver: From physiopathology to therapy.
Schmidt-Arras D, Rose-John S. Schmidt-Arras D, et al. J Hepatol. 2016 Jun;64(6):1403-15. doi: 10.1016/j.jhep.2016.02.004. Epub 2016 Feb 8. J Hepatol. 2016. PMID: 26867490 Free article. Review.
Interleukin 6 (IL-6) is a pleiotropic four-helix-bundle cytokine that exerts multiple functions in the body. ...On target cells IL-6 can bind to the signal transducing subunit gp130 either in complex with the membrane-bound or with the soluble IL-6 rec …
Interleukin 6 (IL-6) is a pleiotropic four-helix-bundle cytokine that exerts multiple functions in the body. ...On target cell …
Interleukin-6: A Masterplayer in the Cytokine Network.
Uciechowski P, Dempke WCM. Uciechowski P, et al. Oncology. 2020;98(3):131-137. doi: 10.1159/000505099. Epub 2020 Jan 20. Oncology. 2020. PMID: 31958792 Review.
IL-6 signaling is mediated by building a complex of IL-6, the transmembrane IL-6 receptor (mIL-6R) or with soluble forms of IL-6R (sIL-6R), and the signal-transducing subunit molecule gp130. ...Vice versa, an overproduction of IL-6 and dysregulation of …
IL-6 signaling is mediated by building a complex of IL-6, the transmembrane IL-6 receptor (mIL-6R) or with soluble form …
IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.
Rose-John S. Rose-John S. Int J Biol Sci. 2012;8(9):1237-47. doi: 10.7150/ijbs.4989. Epub 2012 Oct 24. Int J Biol Sci. 2012. PMID: 23136552 Free PMC article. Review.
Interleukin-6 (IL-6) is a cytokine with many activities. It has functions in the regulation of the immune system and the nervous system. ...On target cells, IL-6 binds to an 80 kDa IL-6 receptor (IL-6R). The complex of IL-6 and IL-6R associates …
Interleukin-6 (IL-6) is a cytokine with many activities. It has functions in the regulation of the immune system and the nervo …
IL-6/IL-6 receptor system and its role in physiological and pathological conditions.
Mihara M, Hashizume M, Yoshida H, Suzuki M, Shiina M. Mihara M, et al. Clin Sci (Lond). 2012 Feb;122(4):143-59. doi: 10.1042/CS20110340. Clin Sci (Lond). 2012. PMID: 22029668 Review.
IL-6 exerts its biological activities through two molecules: IL-6R (IL-6 receptor) and gp130. ...In the present review, we first summarize the IL-6/IL-6R system and IL-6 signal transduction, and then go on to discuss the physiological and pathological …
IL-6 exerts its biological activities through two molecules: IL-6R (IL-6 receptor) and gp130. ...In the present review, we fir …
Mercaptopurine.
[No authors listed] [No authors listed] 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000074 Free Books & Documents. Review.
Thioguanine.
[No authors listed] [No authors listed] 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999719 Free Books & Documents. Review.
It might be desirable to monitor exclusively breastfed infants with a complete blood count with differential, and liver function tests if thioguanine is used during lactation, although some authors feel that monitoring is unnecessary.[1] Most sources consider the thiopurines acce …
It might be desirable to monitor exclusively breastfed infants with a complete blood count with differential, and liver function tests if th …
Therapeutic targeting of IL-6 trans-signaling.
Rose-John S. Rose-John S. Cytokine. 2021 Aug;144:155577. doi: 10.1016/j.cyto.2021.155577. Epub 2021 May 19. Cytokine. 2021. PMID: 34022535 Review.
Interleukin-6 (IL-6) is a cytokine, which is involved in innate and acquired immunity, in neural cell maintenance and in metabolism. ...On target cells, IL-6 binds to an IL-6 receptor, which is not signaling competent. ...
Interleukin-6 (IL-6) is a cytokine, which is involved in innate and acquired immunity, in neural cell maintenance and in metab …
Photoelectron Spectroscopy of the Hexafluorobenzene Cluster Anions: (C(6)F(6)) (n)(-) ( n = 1-5) and I(-)(C(6)F(6)).
Rogers JP, Anstöter CS, Bull JN, Curchod BFE, Verlet JRR. Rogers JP, et al. J Phys Chem A. 2019 Feb 28;123(8):1602-1612. doi: 10.1021/acs.jpca.8b11627. Epub 2019 Feb 14. J Phys Chem A. 2019. PMID: 30694676
Frequency-resolved (2D) photoelectron (PE) spectra of the anionic clusters (C(6)F(6)) (n)(-), for n = 1-5, and time-resolved PE spectra of I(-)C(6)F(6) are presented using a newly built instrument and supported by electronic structure calculations. ... …
Frequency-resolved (2D) photoelectron (PE) spectra of the anionic clusters (C(6)F(6)) (n)(-), for n = 1-5, and time-resolved P …
Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells.
Mackiewicz A, Rose-John S, Schooltink H, Laciak M, Górny A, Heinrich PC. Mackiewicz A, et al. FEBS Lett. 1992 Jul 20;306(2-3):257-61. doi: 10.1016/0014-5793(92)81012-b. FEBS Lett. 1992. PMID: 1321738 Free article.
Interleukin-6 (IL-6) induces changes in gene expression and the N-glycosylation pattern of acute-phase proteins in hepatocytes. ...Stable transfection of IL-6-cDNA into HepG2 cells (HepG2-IL-6) resulting in constitutive secretion of 2 micrograms of IL- …
Interleukin-6 (IL-6) induces changes in gene expression and the N-glycosylation pattern of acute-phase proteins in hepatocytes …
7,582,717 results
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