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The following terms were not found in PubMed: 4-oxadiazol-5-ylmethyl, 7-dihydro-4H-isoxazolo
Unknown fields were ignored: [4,5-c]
Page 1
The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells.
Vanhaecke L, Derycke L, Le Curieux F, Lust S, Marzin D, Verstraete W, Bracke M. Vanhaecke L, et al. Toxicol Lett. 2008 Apr 21;178(1):61-9. doi: 10.1016/j.toxlet.2008.02.004. Epub 2008 Feb 23. Toxicol Lett. 2008. PMID: 18375078
7-Hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) is a newly identified intestinal microbial metabolite from the food carcinogen 2-amino-1-me …
7-Hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimid …
Chemopreventive effects from prebiotic inulin towards microbial 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine bioactivation.
Vanhaecke L, Grootaert C, Verstraete W, Van de Wiele T. Vanhaecke L, et al. J Appl Microbiol. 2009 Feb;106(2):474-85. doi: 10.1111/j.1365-2672.2008.04015.x. J Appl Microbiol. 2009. PMID: 19200315 Free article.
AIMS: Using a Simulator of the Human Intestinal Microbial Ecosystem (SHIME), we investigated the chemopreventive potential of prebiotic chicory inulin towards the in vitro bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human …
AIMS: Using a Simulator of the Human Intestinal Microbial Ecosystem (SHIME), we investigated the chemopreventive potential of prebiotic chic …
Metabolism of Foodborne Heterocyclic Aromatic Amines by Lactobacillus reuteri DSM 20016.
Beer F, Urbat F, Steck J, Huch M, Bunzel D, Bunzel M, Kulling SE. Beer F, et al. J Agric Food Chem. 2017 Aug 16;65(32):6797-6811. doi: 10.1021/acs.jafc.7b01663. Epub 2017 Aug 8. J Agric Food Chem. 2017. PMID: 28679205
The heterocyclic aromatic amine (HAA) 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is converted into 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidi …
The heterocyclic aromatic amine (HAA) 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is converted into 7 …
Isolation and characterization of human intestinal bacteria capable of transforming the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Vanhaecke L, Vercruysse F, Boon N, Verstraete W, Cleenwerck I, De Wachter M, De Vos P, van de Wiele T. Vanhaecke L, et al. Appl Environ Microbiol. 2008 Mar;74(5):1469-77. doi: 10.1128/AEM.02064-07. Epub 2008 Jan 11. Appl Environ Microbiol. 2008. PMID: 18192423 Free PMC article.
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic aromatic amine formed in meat products during cooking. ...In this study, the in vitro conversion of PhIP into its microbial derivate, 7-hydroxy-5-methyl-3 …
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic aromatic amine formed in m …
Intestinal absorption and cell transforming potential of PhIP-M1, a bacterial metabolite of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Nicken P, Willenberg I, Keutz Av, Elsner Lv, Hamscher G, Vanhaecke L, Schröder B, Breves G, Schebb NH, Steinberg P. Nicken P, et al. Toxicol Lett. 2015 Apr 16;234(2):92-8. doi: 10.1016/j.toxlet.2015.02.015. Epub 2015 Feb 20. Toxicol Lett. 2015. PMID: 25707896
Previous studies have shown that in the rat, the colon carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is only absorbed to a limited extent in the small intestines and that a major fraction of unmetabolised PhIP reaches the colon. Mor …
Previous studies have shown that in the rat, the colon carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine …
Metabolism of the food-associated carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human intestinal microbiota.
Vanhaecke L, Van Hoof N, Van Brabandt W, Soenen B, Heyerick A, De Kimpe N, De Keukeleire D, Verstraete W, Van de Wiele T. Vanhaecke L, et al. J Agric Food Chem. 2006 May 3;54(9):3454-61. doi: 10.1021/jf053170+. J Agric Food Chem. 2006. PMID: 16637707
2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a putative human carcinogenic heterocyclic aromatic amine formed from meat and fish during cooking. ...ESI-MS/MS, HRMS, 1D (1H, 13C, DEPT) and 2D (gCOSY, gTOCSY, gHMBC, gHSQC) NMR, and IC analysis eluc …
2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a putative human carcinogenic heterocyclic aromatic amine for …
Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system.
Willenberg I, von Elsner L, Steinberg P, Schebb NH. Willenberg I, et al. Food Chem. 2015 Jan 1;166:537-543. doi: 10.1016/j.foodchem.2014.06.038. Epub 2014 Jun 17. Food Chem. 2015. PMID: 25053091
Heterocyclic aromatic amines such as PHIP are formed during the heat processing of food. PHIP undergoes bacterial metabolism leading to 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin- …
Heterocyclic aromatic amines such as PHIP are formed during the heat processing of food. PHIP undergoes bacterial metabolism leading to 7-hy …
Intestinal bacteria metabolize the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans.
Vanhaecke L, Knize MG, Noppe H, De Brabander H, Verstraete W, Van de Wiele T. Vanhaecke L, et al. Food Chem Toxicol. 2008 Jan;46(1):140-8. doi: 10.1016/j.fct.2007.07.008. Epub 2007 Jul 21. Food Chem Toxicol. 2008. PMID: 17766021
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic amine formed in meats during cooking. ...This study examined the urinary and fecal excretion of a newly identified microbial PhIP metabolite 7-hydroxy-5-methyl …
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic amine formed in meats duri …