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Unknown field was ignored: [4,5-c]
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Analysis of pulmonary vasodilator responses to SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a novel aminofurazan-based Rho kinase inhibitor.
J Pharmacol Exp Ther. 2009 Jul;330(1):334-41. doi: 10.1124/jpet.109.151449. Epub 2009 Apr 15.
J Pharmacol Exp Ther. 2009.
PMID: 19369577
Free PMC article.
The effects of SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], an aminofurazan-based Rho kinase in …
The effects of SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5- …
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.
Doe C, Bentley R, Behm DJ, Lafferty R, Stavenger R, Jung D, Bamford M, Panchal T, Grygielko E, Wright LL, Smith GK, Chen Z, Webb C, Khandekar S, Yi T, Kirkpatrick R, Dul E, Jolivette L, Marino JP Jr, Willette R, Lee D, Hu E.
Doe C, et al.
J Pharmacol Exp Ther. 2007 Jan;320(1):89-98. doi: 10.1124/jpet.106.110635. Epub 2006 Oct 3.
J Pharmacol Exp Ther. 2007.
PMID: 17018693
In this article, we characterized two aminofurazan-based inhibitors, GSK269962A [N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4, 5-c]pyridin-6-yl]oxy}phenyl)-4-{[2-(4-morpholinyl)eth …
In this article, we characterized two aminofurazan-based inhibitors, GSK269962A [N-(3-{[2-(4-amino-1,2,5-oxadiaz …
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New approaches to the treatment of pulmonary hypertension: from bench to bedside.
Murthy SN, Nossaman BD, Kadowitz PJ.
Murthy SN, et al.
Cardiol Rev. 2010 Mar-Apr;18(2):76-84. doi: 10.1097/CRD.0b013e3181cbcbf3.
Cardiol Rev. 2010.
PMID: 20160533
Free PMC article.
Review.
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High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.
Cazzola M, Calzetta L, Rogliani P, Lauro D, Novelli L, Page CP, Kanabar V, Matera MG.
Cazzola M, et al.
Am J Respir Cell Mol Biol. 2012 Oct;47(4):509-16. doi: 10.1165/rcmb.2011-0449OC. Epub 2012 May 31.
Am J Respir Cell Mol Biol. 2012.
PMID: 22652200
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