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Spectroscopic study of 2-, 4- and 5-substituents on pKa values of imidazole heterocycles prone to intramolecular proton-electrons transfer.
Spectrochim Acta A Mol Biomol Spectrosc. 2010 Feb;75(2):693-701. doi: 10.1016/j.saa.2009.11.041. Epub 2009 Nov 24.
Spectrochim Acta A Mol Biomol Spectrosc. 2010.
PMID: 20018554
Experimental studies of the dependence of their protonation/deprotonation equilibrium on substituent identities and intramolecular hydrogen bonding tendencies were carried out using electronic absorption spectroscopy at varying pH values. In order to make comparison, 2-(anthracen …
Experimental studies of the dependence of their protonation/deprotonation equilibrium on substituent identities and intramolecular hydrogen …
Diphenyl imidazole-based fluorescent chemosensor for Al3+ and its Al3+ complex toward water detection in food products.
Liu Y, Li N, Zhang Y, Wang Y.
Liu Y, et al.
Food Chem. 2023 Sep 15;420:136138. doi: 10.1016/j.foodchem.2023.136138. Epub 2023 Apr 11.
Food Chem. 2023.
PMID: 37062081
A sophisticated fluorescent chemosensor, 2-(4-nitrophenyl)-4,5-diphenyl-1H-imidazole (NPDI), was designed and synthesized through a one-step condensation reaction. ...
A sophisticated fluorescent chemosensor, 2-(4-nitrophenyl)-4,5-diphenyl-1H-imidazole (NPDI), was designed …
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In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with neuroprotective role for Alzheimer's disease.
Gurjar AS, Darekar MN, Yeong KY, Ooi L.
Gurjar AS, et al.
Bioorg Med Chem. 2018 May 1;26(8):1511-1522. doi: 10.1016/j.bmc.2018.01.029. Epub 2018 Feb 2.
Bioorg Med Chem. 2018.
PMID: 29429576
Our strategy against AD involves design of multi-targeted 2-substituted-4,5-diphenyl-1H-imidazole analogues which can interact and inhibit AChE, thereby, increasing the synaptic availability of ACh, inhibit BuChE, relieve induced oxidative stres …
Our strategy against AD involves design of multi-targeted 2-substituted-4,5-diphenyl-1H-imidazole analogu …
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