Calix[4]arene-pyrazole conjugates as potential cancer therapeutics.
Muravev AA, Voloshina AD, Sapunova AS, Gabdrakhmanova FB, Lenina OA, Petrov KA, Shityakov S, Skorb EV, Solovieva SE, Antipin IS.
Muravev AA, et al.
Bioorg Chem. 2023 Oct;139:106742. doi: 10.1016/j.bioorg.2023.106742. Epub 2023 Jul 17.
Bioorg Chem. 2023.
PMID: 37480816
Tumor selectivity is yet a challenge in chemotherapy-based cancer treatment. A series of calixarenes derivatized at the lower rim with 3-phenyl-1H-pyrazole units with variable upper-rim substituent and conformations of macrocyclic core, alkyl chain len …
Tumor selectivity is yet a challenge in chemotherapy-based cancer treatment. A series of calixarenes derivatized at the lower rim with 3 …