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The following term was not found in PubMed: -2-phenyl-pentanenitrile
Page 1
(1R,2R)-N-(3-(4-[11C]Methoxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropane-carboxamide.
Leung K. Leung K. 2013 Jan 18 [updated 2013 Apr 11]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2013 Jan 18 [updated 2013 Apr 11]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23586110 Free Books & Documents. Review.
-N-(3-(4-hydroxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropane-carboxamide (LSN2606428) has been shown to inhibit both mGluR1 and mGluR5. Zanotti-Fregonara et al. (9) prepared (1R, 2R)-N-(3-(4-methoxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropan …
-N-(3-(4-hydroxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropane-carboxamide (LSN2606428) has been shown to inhibit both mGluR1 and mGl …
Dimethylamino-3(4-[11C]methoxyphenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one.
Leung K. Leung K. 2012 Dec 5 [updated 2013 Feb 21]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Dec 5 [updated 2013 Feb 21]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23447834 Free Books & Documents. Review.
Several radioligands have been studied for in vivo imaging of the mGluR1 in the brain (5). Dimethylamino-3(4-methoxyphenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one (MMTP) was shown to be selective for the mGluR1, with nanomolar affinity (K(i) = 7.9 n …
Several radioligands have been studied for in vivo imaging of the mGluR1 in the brain (5). Dimethylamino-3(4-methoxyphenyl …
Methyl 3-(4-methoxyphenyl)prop-2-enoate.
Bujak M, Zaleski J, Prezhdo V, Uspenskiy B. Bujak M, et al. Acta Crystallogr C. 2002 Feb;58(Pt 2):o76-7. doi: 10.1107/s0108270101019539. Epub 2002 Jan 16. Acta Crystallogr C. 2002. PMID: 11828113
(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation.
Kim B, Yu JE, Yeo IJ, Son DJ, Lee HP, Roh YS, Lim KH, Yun J, Park H, Han SB, Hong JT. Kim B, et al. Int Immunopharmacol. 2023 Dec;125(Pt A):111124. doi: 10.1016/j.intimp.2023.111124. Epub 2023 Nov 6. Int Immunopharmacol. 2023. PMID: 37977740
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatment prevented the liver sepsis-related mortality induced by 30 mg/kg lipopolysaccharide (LPS) treatment and reduced LPS-induced increase in a …
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatme …
Synthesis of 2,3,4-Trisubstituted 2-Cyclopentenones via Sequential Functionalization of 2-Cyclopentenone.
Gowala TN, Chaudhari P, Pabba J, Sawant K, Pal S, Ghorai SK. Gowala TN, et al. J Org Chem. 2021 Aug 6;86(15):10812-10818. doi: 10.1021/acs.joc.1c01039. Epub 2021 Jul 13. J Org Chem. 2021. PMID: 34255508
The synthesis of differently substituted 2,3,4-triarylcyclopent-2-en-1-ones from 2-cyclopentenone via sequential functionalization of a novel 2,4-dibromo-3-(4-methoxyphenyl) cyclopent-2-en-1-one intermediate has been developed. ...
The synthesis of differently substituted 2,3,4-triarylcyclopent-2-en-1-ones from 2-cyclopentenone via sequential functionalization of a nove …
(E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates MPTP-Induced Dopaminergic Neurodegeneration by Inhibiting the STAT3 Pathway.
Choi JY, Yun J, Hwang CJ, Lee HP, Kim HD, Chun H, Park PH, Choi DY, Han SB, Hong JT. Choi JY, et al. Int J Mol Sci. 2019 May 29;20(11):2632. doi: 10.3390/ijms20112632. Int J Mol Sci. 2019. PMID: 31146332 Free PMC article.
Neuroinflammation is implicated in dopaminergic neurodegeneration. We have previously demonstrated that (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibitor, has a …
Neuroinflammation is implicated in dopaminergic neurodegeneration. We have previously demonstrated that (E)-2-methoxy-4-(3-(4- …
(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3.
Zheng J, Son DJ, Lee HL, Lee HP, Kim TH, Joo JH, Ham YW, Kim WJ, Jung JK, Han SB, Hong JT. Zheng J, et al. Mol Carcinog. 2017 Sep;56(9):2003-2013. doi: 10.1002/mc.22648. Epub 2017 Mar 30. Mol Carcinog. 2017. PMID: 28277616
Interestingly, among the 16 compounds, we found that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) showed the most significant anti-proliferative effect on PA-1 and SK-OV-3 ovarian epithelial cancer cells. ...
Interestingly, among the 16 compounds, we found that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) s …
Structure of 2',6'-dihydroxy-4,4'-dimethoxychalcone.
Schmalle HW, Adiwidjaja G, Jarchow OH, Hausen BM, Wollenweber E. Schmalle HW, et al. Acta Crystallogr C. 1990 Sep 15;46 ( Pt 9):1712-5. doi: 10.1107/s0108270190000221. Acta Crystallogr C. 1990. PMID: 2088422
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-o ne, C17H16O5, Mr = 300.31, orthorhombic, Pbca, a = 27.903 (3), b = 13.958 (2), c = 7.662 (1) A, V = 2984 (1) A3, Z = 8, D chi = 1.337 Mg m-3, lambda(Cu K alpha) = 1.5418 A, mu = 0.729 mm-1, F( …
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-o ne, C17H16O5, Mr = 300.31, orthorhombic, Pbca, a = 2 …
(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates LPS-Mediated Memory Impairment by Inhibition of STAT3 Pathway.
Choi JY, Hwang CJ, Lee DY, Gu SM, Lee HP, Choi DY, Oh KW, Han SB, Hong JT. Choi JY, et al. Neuromolecular Med. 2017 Dec;19(4):555-570. doi: 10.1007/s12017-017-8469-3. Epub 2017 Oct 19. Neuromolecular Med. 2017. PMID: 29052076 Free PMC article.
We tested the anti-inflammatory and anti-amyloidogenic effects of (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibitor. ...
We tested the anti-inflammatory and anti-amyloidogenic effects of (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) …
918 results