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Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12676-94. doi: 10.1002/anie.201402380. Epub 2014 Aug 1.

The principle of membrane fusion in the cell (Nobel lecture).

Author information

  • 1Department of Cell Biology, Yale University, 333 Cedar Street, CT 06520 New Haven (USA).

Abstract

Cells contain small membrane-enclosed vesicles which transport many kinds of cargo between the compartments of the cell. The result is a choreographed program of secretory, biosynthetic, and endocytic protein traffic that serves the cell's internal physiologic needs.

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

KEYWORDS:

Nobel lecture; SNARE; cellular biology; membrane fusion; vesicle transport

PMID:
25087728
[PubMed - in process]
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