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PLoS One. 2014 Jan 21;9(1):e86008. doi: 10.1371/journal.pone.0086008. eCollection 2014.

Single echo MRI.

Author information

  • 1Department of Diagnostic Radiology, Yale University, New Haven, Connecticut, United States of America.
  • 2Department of Diagnostic Radiology, Yale University, New Haven, Connecticut, United States of America ; Department of Biomedical Engineering, Yale University, New Haven, Connecticut, United States of America.

Abstract

PURPOSE:

Previous nonlinear gradient research has focused on trajectories that reconstruct images with a minimum number of echoes. Here we describe sequences where the nonlinear gradients vary in time to acquire the image in a single readout. The readout is designed to be very smooth so that it can be compressed to minimal time without violating peripheral nerve stimulation limits, yielding an image from a single 4 ms echo.

THEORY AND METHODS:

This sequence was inspired by considering the code of each voxel, i.e. the phase accumulation that a voxel follows through the readout, an approach connected to traditional encoding theory. We present simulations for the initial sequence, a low slew rate analog, and higher resolution reconstructions.

RESULTS:

Extremely fast acquisitions are achievable, though as one would expect, SNR is reduced relative to the slower Cartesian sampling schemes because of the high gradient strengths.

CONCLUSIONS:

The prospect that nonlinear gradients can acquire images in a single <10 ms echo makes this a novel and interesting approach to image encoding.

PMID:
24465837
[PubMed - indexed for MEDLINE]
PMCID:
PMC3897604
Free PMC Article
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