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Neuron. 2013 Dec 4;80(5):1103-5. doi: 10.1016/j.neuron.2013.11.016.

Cortical projection neurons: sprung from the same root.

Author information

  • 1Department of Neurobiology and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA.

Abstract

Whether cortical projection neurons (CPNs) are generated by multipotent or fate-restricted progenitors is not completely understood. In this issue of Neuron, Guo et al. (2013) provide evidence that mouse Fezf2-expressing radial glial cells are multipotent progenitors that sequentially generate all major CPN subtypes and glia.

Copyright © 2013 Elsevier Inc. All rights reserved.

PMID:
24314721
[PubMed - indexed for MEDLINE]
PMCID:
PMC3951749
Free PMC Article
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