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Lab Chip. 2013 Nov 7;13(21):4160-3. doi: 10.1039/c3lc50571e.

A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface.

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  • 1Dept. of Diagnostic Radiology, Yale University, New Haven, CT, USA. michael.choma@yale.edu.

Abstract

From the lungs to the central nervous system, cilia-driven fluid flow plays a fundamental role in many facets of life. Yet, there are few quantitative methods for analysing the function of ciliated surfaces. Here, we report a novel microfluidic approach for quantifying the performance of a ciliated surface using mixing performance as an integrated readout.

PMID:
23970350
[PubMed - indexed for MEDLINE]
PMCID:
PMC3856250
Free PMC Article
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