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Pediatr Dermatol. 2014 Sep-Oct;31(5):595-8. doi: 10.1111/pde.12090. Epub 2013 Mar 5.

Congenital kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon successfully treated with low-dose radiation therapy.

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  • 1Division of Neonatology, Yale University, New Haven, Connecticut; Division of Neonatology, Maria Fareri Children's Hospital, New York Medical College, Westchester, New York.


Kaposiform hemangioendothelioma (KHE) associated with Kasabach-Merritt phenomenon is a life-threatening vasculopathy. The current mainstay treatment for KHEs is corticosteroids and chemotherapy, but these medications do not work for all patients and carry significant side effects. We report a neonate with a large congenital KHE who responded extremely well to low-dose radiation therapy.

© 2013 Wiley Periodicals, Inc.

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