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Am J Reprod Immunol. 2013 Mar;69(3):195-6. doi: 10.1111/aji.12073.

Viral invasion of the amniotic cavity (VIAC) in the midtrimester of pregnancy.

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  • 1Department of Obstetrics, Gynecology and Reproductive Sciences, Reproductive Immunology Unit, Yale University School of Medicine, New Haven, CT 06250, USA.


A role for microbial invasion leading to inflammation in the amniotic cavity and subsequent pre-term delivery has been well established. For years, the role of viral infections in pregnancy has been minimized and thought of as harmless, with a few exceptions. Recent evidence now encourages us to expand our thinking and realize that viral infections during pregnancy may influence pregnancy more that we thought.

© 2013 John Wiley & Sons A/S.

[PubMed - indexed for MEDLINE]
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