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Am J Reprod Immunol. 2012 Oct;68(4):279-81. doi: 10.1111/aji.12006. Epub 2012 Aug 31.

Decidual stromal cells as regulators of T-cell access to the maternal-fetal interface.

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  • 1Reproductive Immunology Unit, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.

Abstract

A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical conditions, including cancer and pregnancies affected by infection or autoimmunity.

© 2012 John Wiley & Sons A/S.

PMID:
22935072
[PubMed - indexed for MEDLINE]
PMCID:
PMC3703652
Free PMC Article
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