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Clin Chest Med. 2012 Mar;33(1):123-49. doi: 10.1016/j.ccm.2012.01.004.

Interstitial lung disease in the connective tissue diseases.

Author information

  • 1Yale Interstitial Lung Disease Program, Pulmonary & Critical Care Medicine Section, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA. danielle.antin-ozerkis@yale.edu

Abstract

The connective tissue diseases (CTDs) are inflammatory, immune-mediated disorders in which interstitial lung disease (ILD) is common and clinically important. Interstitial lung disease may be the first manifestation of a CTD in a previously healthy patient. CTD-associated ILD frequently presents with the gradual onset of cough and dyspnea, although rarely may present with fulminant respiratory failure. Infection and drug reaction should always be ruled out. A diagnosis of idiopathic ILD should never be made without a careful search for subtle evidence of underlying CTD. Treatment of CTD-ILD typically includes corticosteroids and immunosuppressive agents.

Copyright © 2012 Elsevier Inc. All rights reserved.

PMID:
22365251
[PubMed - indexed for MEDLINE]
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