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Bioinformatics. 2012 Feb 15;28(4):589-90. doi: 10.1093/bioinformatics/btr700. Epub 2011 Dec 22.

htSeqTools: high-throughput sequencing quality control, processing and visualization in R.

Author information

  • 1Biostatistics and Bioinformatics Unit, Institute for Research in Biomedicine of Barcelona, Barcelona, Spain.

Abstract

We provide a Bioconductor package with quality assessment, processing and visualization tools for high-throughput sequencing data, with emphasis in ChIP-seq and RNA-seq studies. It includes detection of outliers and biases, inefficient immuno-precipitation and overamplification artifacts, de novo identification of read-rich genomic regions and visualization of the location and coverage of genomic region lists.

AVAILABILITY:

www.bioconductor.org.

PMID:
22199381
[PubMed - indexed for MEDLINE]
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