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Cell. 2011 Oct 28;147(3):489-91. doi: 10.1016/j.cell.2011.10.004.

You AhR what you eat: linking diet and immunity.

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  • The Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. lora.hooper@utsouthwestern.edu

Abstract

The aryl hydrocarbon receptor (AhR) is responsible for the toxic effects of environmental pollutants such as dioxin, but little is known about its normal physiological functions. Li et al. (2011) now show that specific dietary compounds present in cruciferous vegetables act through the AhR to promote intestinal immune function, revealing AhR as a critical link between diet and immunity.

Copyright © 2011 Elsevier Inc. All rights reserved.

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PMID:
22036556
[PubMed]
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