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Horm Res Paediatr. 2011;76 Suppl 1:47-51. doi: 10.1159/000329163. Epub 2011 Jul 21.

Screening and treatment of dyslipidemias in children and adolescents.

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  • 1Department of Pediatrics, University of Colorado, Denver School of Medicine, Aurora, CO 80045, USA.



Cardiovascular disease is the most prominent cause of mortality worldwide. A key risk factor for atherosclerotic cardiovascular disease is the presence of dyslipidemia. Clinical approaches to evaluation and treatment of dyslipidemia in children and adolescents are presented.


A review of published guidelines and presentation of illustrative cases.


Dyslipidemia is an important risk factor in early-stage atherosclerosis. Children and adolescents at high risk for dyslipidemia can be identified using a positive family history or the presence of other risk factors as a trigger. Once high-risk individuals are identified, primary treatment is lifestyle modification. In cases where low-density lipoprotein-cholesterol is high, pharmacologic intervention may be needed.


Screening of appropriate children and adolescents for dyslipidemia and treating those at high risk are important for the long-term prevention of cardiovascular disease.

Copyright © 2011 S. Karger AG, Basel.

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