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Yale J Biol Med. 2010 Sep;83(3):135-7.

Five classic articles in somatic cell reprogramming.

Author information

  • 1Department of Genetics, Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad 201B, New Haven, CT 06520, USA. inhyun.park@yale.edu

Abstract

Research on somatic cell reprogramming has progressed significantly over the past few decades, from nuclear transfer into frogs' eggs in 1952 to the derivation of human-induced pluripotent stem (iPS) cells in the present day. In this article, I review five landmark papers that have laid the foundation for current efforts to apply somatic cell reprogramming in the clinic.

PMID:
20885901
[PubMed - indexed for MEDLINE]
PMCID:
PMC2946127
Free PMC Article
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