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Cell. 2010 Jun 25;141(7):1110-2. doi: 10.1016/j.cell.2010.06.014.

Retrotransposition and structural variation in the human genome.

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  • 1Department of Molecular and Human Genetics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX 77030, USA.

Abstract

New assays are revealing that the diploid human genome contains extensive amounts of structural variation. Genome-wide approaches described in three papers in this issue (Beck et al., 2010; Huang et al., 2010; Iskow et al., 2010) paint a dynamic portrait of our genome, revealing a prominent role for repetitive sequences in shaping its structural variation.

PMID:
20602993
[PubMed]
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