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Nat Cell Biol. 2010 Feb;12(2):102-4. doi: 10.1038/ncb0210-102. Epub 2010 Jan 17.

Tipping the scale: muscle versus fat.

Author information

  • 1Section of Comparative Medicine, Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06520, USA.

Erratum in

  • Nat Cell Biol. 2010 Mar;12(3):306.


Adipocytes and scar tissue form during skeletal muscle degeneration. Two new studies reveal that adipocytes and fibroblasts in skeletal muscle derive from a population of bipotent progenitors that reside within muscle, but are not derived from the muscle lineage. These progenitor cells also have a surprising role in stimulating the restoration of muscle mass during regeneration.

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