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The following terms were ignored: [, ]
The following terms were not found in PubMed: 3-methylsulfanylphenyl, 1-dioxo-pyrido, thiadiazin-3-one
Unknown fields were ignored: [2,3-e]
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Synthesis and anti-HIV activity evaluation of novel 2,4-disubstituted 7-methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo-[4,5-e][1,2]thiadiazines.
Liu XY, Yan RZ, Wang Y, Zhan P, De Clercq E, Pannecouque C, Witvrouw M, Molina MT, Vega S. Liu XY, et al. Arch Pharm (Weinheim). 2008 Apr;341(4):216-22. doi: 10.1002/ardp.200700216. Arch Pharm (Weinheim). 2008. PMID: 18266290
A series of novel 2,4-disubstituted 7-methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo[4,5-e] [1,2,4]thiadiazines (PTDs) was synthesized, structurally confirmed by spectral analysis, and evaluated for their anti-HIV activities by inhibition of HIV-induc …
A series of novel 2,4-disubstituted 7-methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo[4,5-e] [1,2,4]thiadiazines …
1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.
Witvrouw M, Arranz ME, Pannecouque C, Declercq R, Jonckheere H, Schmit JC, Vandamme AM, Diaz JA, Ingate ST, Desmyter J, Esnouf R, Van Meervelt L, Vega S, Balzarini J, De Clercq E. Witvrouw M, et al. Antimicrob Agents Chemother. 1998 Mar;42(3):618-23. doi: 10.1128/AAC.42.3.618. Antimicrob Agents Chemother. 1998. PMID: 9517942 Free PMC article.
We report the development of a new group of nonnucleoside reverse transcriptase inhibitors (NNRTIs). One of the most active congeners of this series of 1,1,3-trioxo-2H,4H-thieno[3,4-e] [1,2,4]thiadiazine (TTD) derivatives, i.e., 2-(3-fluorobenzy …
We report the development of a new group of nonnucleoside reverse transcriptase inhibitors (NNRTIs). One of the most active congeners of thi …