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1-(2-(2-(2-(1-Aminoethyl)phenyl)diselanyl)phenyl)ethanamine: an amino organoselenium compound with interesting antioxidant profile.
Ibrahim M, Hassan W, Anwar J, Deobald AM, Kamdem JP, Souza DO, Rocha JB. Ibrahim M, et al. Toxicol In Vitro. 2014 Jun;28(4):524-30. doi: 10.1016/j.tiv.2013.12.010. Epub 2014 Jan 4. Toxicol In Vitro. 2014. PMID: 24394197
Free radical scavenging and antioxidant activities of 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethanamine (compound A) and diphenyl diselenide (PhSe)2 were examined and compared for inhibition of Fe(II) and sodium nitroprusside (S …
Free radical scavenging and antioxidant activities of 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethana …
Two newly-emerging substituted phenethylamines MAL and BOD induce differential psychopharmacological effects in rodents.
Custodio RJP, Sayson LV, Botanas CJ, Abiero A, Kim M, Lee HJ, Ryu HW, Lee YS, Kim HJ, Cheong JH. Custodio RJP, et al. J Psychopharmacol. 2020 Sep;34(9):1056-1067. doi: 10.1177/0269881120936458. Epub 2020 Jul 10. J Psychopharmacol. 2020. PMID: 32648801
BACKGROUND: Recently, the recreational use of substituted phenethylamines has grown rapidly. Among these are 2-(3,5-dimethoxy-4-((2-methylallyl)oxy)phenyl)ethanamine (MAL) and 2-(2,5-dimethoxy-4-methylphenyl)-2-methoxyethan-1-amine …
BACKGROUND: Recently, the recreational use of substituted phenethylamines has grown rapidly. Among these are 2-(3,5-dimethoxy-4-(( …
Acute oral toxicity and antioxidant studies of an amine-based diselenide.
Ibrahim M, Muhammad N, Ibrahim M, Khan MI, Shah MIA, Said M, Khan W, Kamdem JP, Rocha JBT. Ibrahim M, et al. BMC Complement Altern Med. 2019 Apr 3;19(1):80. doi: 10.1186/s12906-019-2489-5. BMC Complement Altern Med. 2019. PMID: 30943970 Free PMC article.
The antioxidant activity and acute toxicity of an organoselenium compound, 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethanamine (APDP) was determined in mice. ...
The antioxidant activity and acute toxicity of an organoselenium compound, 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl) …
A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action.
Mignani S, El Brahmi N, El Kazzouli S, Eloy L, Courilleau D, Caron J, Bousmina MM, Caminade AM, Cresteil T, Majoral JP. Mignani S, et al. Eur J Med Chem. 2016 Oct 21;122:656-673. doi: 10.1016/j.ejmech.2016.05.063. Epub 2016 Jun 11. Eur J Med Chem. 2016. PMID: 27448922
Reduction of the alpha-beta double bond of EA completely abolished anti-cancer activities, whereas introduction of either 2-(4-substituted phenyl)ethanamine (series A) or 4-(4-substituted phenyl)piperazine (series B) moieties generated compounds showing moder …
Reduction of the alpha-beta double bond of EA completely abolished anti-cancer activities, whereas introduction of either 2-(4-substi …