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The following term was not found in PubMed: 6-dimethylbenzofuran-3-yl
Page 1
Convenient Synthesis of N-Alkyl-2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetamides and Methyl-2-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetylamino]alkanoates.
El Rayes SM, El-Enany G, Gomaa MS, Ali IAI, Fathalla W, Pottoo FH, Khan FA. El Rayes SM, et al. ACS Omega. 2022 Sep 15;7(38):34166-34176. doi: 10.1021/acsomega.2c03522. eCollection 2022 Sep 27. ACS Omega. 2022. PMID: 36188256 Free PMC article.
A series of 27 new quinoxaline derivatives (N-alkyl-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)]acetamides, methyl-2-[2-(3-phenylquinoxalin-2-ylsulfanyl)-acetylamino]alkanoates, and their corresponding dipeptides) were prepared from 3-ph …
A series of 27 new quinoxaline derivatives (N-alkyl-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)]acetamides, methyl- …
Amino Alcohol Acrylonitriles as Activators of the Aryl Hydrocarbon Receptor Pathway: An Unexpected MTT Phenotypic Screening Outcome.
Baker JR, Russell CC, Gilbert J, Sakoff JA, McCluskey A. Baker JR, et al. ChemMedChem. 2020 Mar 18;15(6):490-505. doi: 10.1002/cmdc.201900643. Epub 2020 Feb 28. ChemMedChem. 2020. PMID: 32012442
Lead (Z)-N-(4-(2-cyano-2-(3,4-dichlorophenyl)vinyl)phenyl)acetamide, 1 showed MCF-7 GI(50) =30 nM and 400-fold selective c.f. ...But, these data did not fit our homology modelling expectations. Aberrant MTT ((3-[4,5-dimet …
Lead (Z)-N-(4-(2-cyano-2-(3,4-dichlorophenyl)vinyl)phenyl)acetamide, 1 showed MCF-7 GI(50) =30 nM …
Disrupting Y-Box-Binding Protein 1 Function Using OSU-03012 Prevents Endometriosis Progression in In Vitro and In Vivo Models.
Silveira CGT, Marschner G, Canny GO, Klocke S, Hunold P, Köster F, Ahrens T, Rody A, Hornung D. Silveira CGT, et al. Reprod Sci. 2017 Jan;24(1):67-76. doi: 10.1177/1933719116649695. Epub 2016 Sep 27. Reprod Sci. 2017. PMID: 27217374
The objective of the present study was to test the ability of OSU-03012 (2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide), a novel and potent celecoxib-derivative, to impair endometriosis progression in in vitro …
The objective of the present study was to test the ability of OSU-03012 (2-amino-N-[4-[5-phenanthren-2-yl-3-(tri …
2-Hydroxymelatonin, a Predominant Hydroxylated Melatonin Metabolite in Plants, Shows Antitumor Activity against Human Colorectal Cancer Cells.
Yang Y, Zhou R, Park SY, Back K, Bae WK, Kim KK, Kim H. Yang Y, et al. Molecules. 2017 Mar 14;22(3):453. doi: 10.3390/molecules22030453. Molecules. 2017. PMID: 28335402 Free PMC article.
2-Hydroxymelatonin is a predominant hydroxylated melatonin metabolite in plants. To investigate whether it has potent cytotoxic effects on colorectal cancer cells, four colorectal cancer cell lines, Caco2, HCT116, DLD1, and CT26, were treated with 2-hydroxymelatonin …
2-Hydroxymelatonin is a predominant hydroxylated melatonin metabolite in plants. To investigate whether it has potent cytotoxic effec …
Some Thiazole Derivatives Combined with Different Heterocycles: Cytotoxicity Evaluation and Apoptosis Inducing Studies.
Yurttaş L, Demir B, Çiftçi GA. Yurttaş L, et al. Anticancer Agents Med Chem. 2018;18(8):1115-1121. doi: 10.2174/1871520618666180328115314. Anticancer Agents Med Chem. 2018. PMID: 29595114
OBJECTIVE: Some thiazole compounds combined with different heterocyclic rings were acquired in this study. Novel 5-(4-substituted benzylidene)-2-[(4,5-dimethylthiazol-2-yl)amino]thiazol-4(5H)-one derivatives (4a-g) and 2 …
OBJECTIVE: Some thiazole compounds combined with different heterocyclic rings were acquired in this study. Novel 5-(4-substituted ben …
Effects of A2BR on the biological behavior of mouse renal fibroblasts during hypoxia.
Tang J, Jiang X, Zhou Y, Dai Y. Tang J, et al. Mol Med Rep. 2015 Jun;11(6):4397-402. doi: 10.3892/mmr.2015.3320. Epub 2015 Feb 9. Mol Med Rep. 2015. PMID: 25672943
Cells were divided into the following four groups: i) Control; ii) 5'-N-ethylcarboxamidoadenosine (NECA); iii) PT, NECA + 8-phenyltheophylline (PT); and iv) MRS, NECA + N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipro …
Cells were divided into the following four groups: i) Control; ii) 5'-N-ethylcarboxamidoadenosine (NECA); iii) PT, NECA + 8-phenylthe …
Synthesis, Characterization, and Biological Activity of a Novel Series of Benzo[4,5]imidazo[2,1-b]thiazole Derivatives as Potential Epidermal Growth Factor Receptor Inhibitors.
Deng X, Tan X, An T, Ma Q, Jin Z, Wang C, Meng Q, Hu C. Deng X, et al. Molecules. 2019 Feb 14;24(4):682. doi: 10.3390/molecules24040682. Molecules. 2019. PMID: 30769844 Free PMC article.
Based on the analysis of epidermal growth factor receptor (EGFR) complexes with gefitinib with molecular docking, the scaffold-hopping strategy, combination of the active substructures, and structural optimization of EGFR inhibitors, a novel series of benzo[4,5]imidazo[ …
Based on the analysis of epidermal growth factor receptor (EGFR) complexes with gefitinib with molecular docking, the scaffold-hopping strat …
Antiestrogenic Activity and Possible Mode of Action of Certain New Nonsteroidal Coumarin-4-acetamides.
Almutairi MS, Al Suwayyid AN, Aldarwesh A, Aboulwafa OM, Attia MI. Almutairi MS, et al. Molecules. 2020 Mar 28;25(7):1553. doi: 10.3390/molecules25071553. Molecules. 2020. PMID: 32231072 Free PMC article.
The preparation of certain 2-(2-oxo-2H-chromen-4-yl)-N-substituted acetamides IIIa-h was planned as a step in the development of new modified nonsteroidal antiestrogens. The purity of target compounds IIIa-h was checked by thin-layer chromatogra …
The preparation of certain 2-(2-oxo-2H-chromen-4-yl)-N-substituted acetamides IIIa-h was planned as a ste …
Synthesis, antimicrobial activity and cytotoxicity of novel oxadiazole derivatives.
Kaplancikli ZA, Altintop MD, Turan-Zitouni G, Ozdemir A, Ozic R, Akalin G. Kaplancikli ZA, et al. J Enzyme Inhib Med Chem. 2012 Feb;27(1):51-7. doi: 10.3109/14756366.2011.574132. Epub 2011 May 3. J Enzyme Inhib Med Chem. 2012. PMID: 21534862
N-(Benzothiazol-2-yl)-2-[[5-substituted-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide derivatives (3a-j) were obtained by the nucleophilic substitution reactions of 5-substituted-1,3,4-oxadiazolin-2-thiones (1a-b) with N-(b …
N-(Benzothiazol-2-yl)-2-[[5-substituted-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide derivatives (3a-j) …
Ruthenium(III) maltolato-nitroimidazole complexes: synthesis and biological activity.
Kennedy DC, Wu A, Patrick BO, James BR. Kennedy DC, et al. J Inorg Biochem. 2006 Dec;100(12):1974-82. doi: 10.1016/j.jinorgbio.2006.07.001. Epub 2006 Jul 25. J Inorg Biochem. 2006. PMID: 16938347
The Ru(III) metronidazole-maltolato and -ethylmaltolato complexes, trans-[RuL(2)(metro)(2)]CF(3)SO(3) (L=ma (1a) or etma (1b)), have been synthesized and tested for potential anti-tumour activity against the human breast cancer cell line MDA-MB-435S using a so-calle …
The Ru(III) metronidazole-maltolato and -ethylmaltolato complexes, trans-[RuL(2)(metro)(2)]CF(3)SO(3) (L=ma (1a) or etma (1b)) …
14 results