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The following term was not found in PubMed: 9-Tetrahydro-1H-beta-carboline-3-carboxylic
Page 1
Moexipril.
[No authors listed] [No authors listed] 2019 Feb 28. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2019 Feb 28. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000094 Free Books & Documents. Review.
Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.
Nizam Mohideen M, Rasheeth A, Huq CA, Nizar SS. Nizam Mohideen M, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 13;64(Pt 9):o1752. doi: 10.1107/S1600536808025610. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21201734 Free PMC article.
The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra-hydro-pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. ...
The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra-hydro-pyrimidin …
2-Oxo-1,2,3,4-tetrahydropyrimidines Ethyl Esters as Potent beta- Glucuronidase Inhibitors: One-pot Synthesis, In vitro and In silico Studies.
Iqbal S, Shaikh NN, Khan KM, Naz S, Ul-Haq Z, Perveen S, Choudhary MI. Iqbal S, et al. Med Chem. 2018;14(8):818-830. doi: 10.2174/1573406414666180525105325. Med Chem. 2018. PMID: 29793412
METHOD: We synthesized a series of 2-oxo-1,2,3,4-tetrahydropyrimidines 1-25 by fusing urea, ethyl acetoacetate, and a variety of aldehydes using copper nitrate trihydrate as catalyst. ...Docking results highlighted the role of various chemical moieties …
METHOD: We synthesized a series of 2-oxo-1,2,3,4-tetrahydropyrimidines 1-25 by fusing urea, ethyl acetoacetate, …
Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection.
Lecanu L, Tillement L, McCourty A, Rammouz G, Yao W, Greeson J, Papadopoulos V. Lecanu L, et al. Med Chem. 2010 May;6(3):123-40. doi: 10.2174/1573406411006030123. Med Chem. 2010. PMID: 20438444
We report herein the synthesis and biological evaluation of dimethyl-carbamic acid 2,3-bis-dimethylcarbamoyloxy-6-(4-ethyl-piperazine-1-carbonyl)-phenyl ester (SP-04), a new drug candidate that is designed to offer a multi-target therapeutic neuroprotective a …
We report herein the synthesis and biological evaluation of dimethyl-carbamic acid 2,3-bis-dimethylcarbamoyloxy-6-(4-ethyl-pip …
Synthesis of 3-(3-pyridyl)- and 3-(3-benzo[b]thienyl)-D-alanine.
Rao PN, Burdett JE Jr, Cessac JW, DiNunno CM, Peterson DM, Kim HK. Rao PN, et al. Int J Pept Protein Res. 1987 Jan;29(1):118-25. doi: 10.1111/j.1399-3011.1987.tb02237.x. Int J Pept Protein Res. 1987. PMID: 3570651
The DL-arylamino acid ethyl ester derivatives of beta-(3-pyridyl)-DL-alanine, and beta-(3-benzo[b]thienyl)-DL-alanine were synthesized by diethyl acetamidomalonate condensation with the respective arylmethyl halides followed by partial hydrolysis to the monoe …
The DL-arylamino acid ethyl ester derivatives of beta-(3-pyridyl)-DL-alanine, and beta-(3-benzo[b]thienyl)-DL-alanine w …
Synthesis of 4-deoxy-4-nitrosialic acid.
Hemeon I, Bennet AJ. Hemeon I, et al. Org Biomol Chem. 2006 Aug 7;4(15):2986-92. doi: 10.1039/b605218e. Epub 2006 Jul 5. Org Biomol Chem. 2006. PMID: 16855749
Coupling of the 6-carbon fragment, 2-acetamido-1,2-dideoxy-1-nitro-D-mannitol (6) with ethyl alpha-(bromomethyl)acrylate afforded a 2 : 1 mixture of ethyl 5-acetamido-2,3,4,5-tetradeoxy-2-methylene-4-nitro-D-glycero-D-galacto-nononate (9a-S) and …
Coupling of the 6-carbon fragment, 2-acetamido-1,2-dideoxy-1-nitro-D-mannitol (6) with ethyl alpha-(bromomethyl)acrylate afforded a 2 …
Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl esters.
Sharma SK, Kumar P, Narasimhan B, Ramasamy K, Mani V, Mishra RK, Majeed AB. Sharma SK, et al. Eur J Med Chem. 2012 Feb;48:16-25. doi: 10.1016/j.ejmech.2011.11.028. Epub 2011 Nov 22. Eur J Med Chem. 2012. PMID: 22154835
A series of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl esters (1-16) were synthesized and evaluated in vitro for their antimicrobial and anticancer pot …
A series of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5 …
Orally active opioid compounds from a non-poppy source.
Raffa RB, Beckett JR, Brahmbhatt VN, Ebinger TM, Fabian CA, Nixon JR, Orlando ST, Rana CA, Tejani AH, Tomazic RJ. Raffa RB, et al. J Med Chem. 2013 Jun 27;56(12):4840-8. doi: 10.1021/jm400143z. Epub 2013 Apr 8. J Med Chem. 2013. PMID: 23517479 Review.
Specifically, at least two alkaloids isolated from the plant Mitragyna speciosa, mitragynine ((E)-2-[(2S,3S)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[3,2-h]quinolizin-2-yl]-3-methoxyprop-2-enoic acid methyl ester; 9-methoxy co …
Specifically, at least two alkaloids isolated from the plant Mitragyna speciosa, mitragynine ((E)-2-[(2S,3S)-3-ethyl-8-methoxy-1,2 …
Antileukemic effect of caffeic acid 3,4-dihydroxyphenetyl ester. Evidences for its mechanisms of action.
Tang M, Xie X, Shi M, Xin W, Zheng G, Zhang Y, Zhang Z, Lian X. Tang M, et al. Phytomedicine. 2021 Jan;80:153383. doi: 10.1016/j.phymed.2020.153383. Epub 2020 Oct 13. Phytomedicine. 2021. PMID: 33091855
BACKGROUND: Caffeic acid 3,4-dihydroxyphenethyl ester (CADPE) is a natural polyphenolic ester isolated as a minor component from a water extract of the Chinese medicine Zhongjiefeng [Sarcandra glabra (Thunb.) ...
BACKGROUND: Caffeic acid 3,4-dihydroxyphenethyl ester (CADPE) is a natural polyphenolic ester isolated as a minor compo …
Disposition and metabolism of the angiotensin-converting enzyme inhibitor [4S-[4 alpha, 7 alpha, (R*), 12b beta]]-7-[S-(1-ethoxycarbonyl-3- phenylpropyl)amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo- pyrido[2,1-a][2]benzazepine-4-carboxylic acid in monkeys and dogs.
Cheng H, Stuhler JD, Dorrbecker BR, Gordon WP. Cheng H, et al. Drug Metab Dispos. 1991 Jan-Feb;19(1):212-7. Drug Metab Dispos. 1991. PMID: 1673401
[4S-[4 alpha, 7 alpha, (R*),12b beta]]-7-[S- (1-ethoxycarbonyl-3-phenylpropyl)amino]-1,2,3,4,6,7,8, 12b-octahydro-6-oxo-pyrido[2,1-a][2]benzazepine-4-carboxylic acid (MDL 27,210) is the ethyl ester prodrug of a potent angiotensin-converti …
[4S-[4 alpha, 7 alpha, (R*),12b beta]]-7-[S- (1-ethoxycarbonyl-3-phenylpropyl)amino]-1,2,3,4,6,7,8, 12b-octahydro-6-oxo …
121 results