Circ Arrhythm Electrophysiol. 2008 Jun 1;1(2):80-2. doi: 10.1161/CIRCEP.108.791434.

Dilated cardiomyopathy due to sodium channel dysfunction: what is the connection?

Bezzina CR, Remme CA.

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Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy. [Circ Arrhythm Electrophysiol. 2008]
Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy.Ge J, Sun A, Paajanen V, Wang S, Su C, Yang Z, Li Y, Wang S, Jia J, Wang K, et al. Circ Arrhythm Electrophysiol. 2008 Jun 1; 1(2):83-92. Epub 2008 Apr 30.

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The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death. [Europace. 2008]
The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death.
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Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy. [Circ Arrhythm Electrophysiol. ...]
Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy.
Ge J, Sun A, Paajanen V, Wang S, Su C, Yang Z, Li Y, Wang S, Jia J, Wang K, et al. Circ Arrhythm Electrophysiol. 2008 Jun 1; 1(2):83-92. Epub 2008 Apr 30.
Review [The cardiac sodium channel gene SCN5A mutation and dilated cardiomyopathy]. [Sheng Li Ke Xue Jin Zhan. 2010]
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Cited by 3 PubMed Central articles

Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. [Circulation. 2011]
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SCN5A rare variants in familial dilated cardiomyopathy decrease peak sodium current depending on the common polymorphism H558R and common splice variant Q1077del. [Clin Transl Sci. 2010]
SCN5A rare variants in familial dilated cardiomyopathy decrease peak sodium current depending on the common polymorphism H558R and common splice variant Q1077del.
Cheng J, Morales A, Siegfried JD, Li D, Norton N, Song J, Gonzalez-Quintana J, Makielski JC, Hershberger RE. Clin Transl Sci. 2010 Dec; 3(6):287-94.
Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels. [Cardiovasc Res. 2009]
Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels.
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Dilated cardiomyopathy due to sodium channel dysfunction: what is the connection...
Dilated cardiomyopathy due to sodium channel dysfunction: what is the connection?
Circ Arrhythm Electrophysiol. 2008 Jun 1 ;1(2):80-2. doi: 10.1161/CIRCEP.108.791434.

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