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J Vis Exp. 2008 Nov 13;(21). pii: 992. doi: 10.3791/992.

Functional imaging with reinforcement, eyetracking, and physiological monitoring.

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  • 1Department of Neuroscience, Columbia University, USA.

Abstract

We use functional brain imaging (fMRI) to study neural circuits that underlie decision-making. To understand how outcomes affect decision processes, simple perceptual tasks are combined with appetitive and aversive reinforcement. However, the use of reinforcers such as juice and airpuffs can create challenges for fMRI. Reinforcer delivery can cause head movement, which creates artifacts in the fMRI signal. Reinforcement can also lead to changes in heart rate and respiration that are mediated by autonomic pathways. Changes in heart rate and respiration can directly affect the fMRI (BOLD) signal in the brain and can be confounded with signal changes that are due to neural activity. In this presentation, we demonstrate methods for administering reinforcers in a controlled manner, for stabilizing the head, and for measuring pulse and respiration.

PMID:
19066528
[PubMed - indexed for MEDLINE]
PMCID:
PMC2731772
Free PMC Article
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