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Trends Cardiovasc Med. 2006 Jul;16(5):153-6.

Blood vessels engineered from human cells.

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  • 1Department of Anesthesia, Duke University, Durham, NC 27708, USA.


Human vascular tissue engineering has progressed substantially over the past decade. Issues remain as to the optimum culture scaffold and cell source that should be used for arterial regeneration. In addition, limitations in replicative life span of adult human cells as compared with young animal cells have made human vascular tissue engineering more challenging. Despite these obstacles, several strategies for generating replacement vessels have progressed to clinical trials.

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