Cloning and sequencing of RNA of hepatitis delta virus isolated from human serum

J A Saldanha; H C Thomas; J P Monjardino

doi:10.1099/0022-1317-71-7-1603

Cloning and sequencing of RNA of hepatitis delta virus isolated from human serum

J Gen Virol. 1990 Jul:71 ( Pt 7):1603-6. doi: 10.1099/0022-1317-71-7-1603.

Authors

J A Saldanha¹, H C Thomas, J P Monjardino

Affiliation

¹ Department of Medicine, St Mary's Hospital Medical School, London, U.K.

PMID: 2374010
DOI: 10.1099/0022-1317-71-7-1603

Abstract

The RNA of hepatitis delta virus (HDV) 1682 nucleotides long, has been cloned from a human serum isolate. Comparison with the three complete published sequences shows that a region of the HDV genome, between positions 620 and 1350, which contains sequences involved in replication and possibly pathogenicity, is highly conserved.

Publication types

Comparative Study

MeSH terms

Animals
Base Sequence
Cloning, Molecular
Genes, Viral
Hepatitis D / blood
Hepatitis D / microbiology
Hepatitis Delta Virus / genetics*
Hepatitis Delta Virus / isolation & purification
Humans
Molecular Sequence Data
Pan troglodytes
RNA, Viral / genetics*
Sequence Homology, Nucleic Acid
Viroids / genetics

Substances

RNA, Viral