The A-MYSM power of deubiquitinases

Ignacio A Demarco; Harinder Singh

doi:10.1016/j.immuni.2011.12.009

The A-MYSM power of deubiquitinases

Immunity. 2011 Dec 23;35(6):847-9. doi: 10.1016/j.immuni.2011.12.009.

Authors

Ignacio A Demarco¹, Harinder Singh

Affiliation

¹ Department of Discovery Immunology, Genentech, South San Francisco, CA 94080, USA.

PMID: 22195739
DOI: 10.1016/j.immuni.2011.12.009

Abstract

Little is known about the developmental functions of chromatin regulators that can deubiquitinate histones. In this issue of Immunity, Jiang et al. (2011) demonstrate that the deubiquitinase MYSM1 is part of an epigenetic switch that turns on B cell development.

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