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    Results: 1 to 20 of 56

    1.

    T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma.

    Imajyo I, Sugiura T, Kobayashi Y, Shimoda M, Ishii K, Akimoto N, Yoshihama N, Kobayashi I, Mori Y.

    Int J Oncol. 2012 Dec;41(6):1985-95. doi: 10.3892/ijo.2012.1673. Epub 2012 Oct 17.

    PMID:
    23076115
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.

    Nelson AC, Pillay N, Henderson S, Presneau N, Tirabosco R, Halai D, Berisha F, Flicek P, Stemple DL, Stern CD, Wardle FC, Flanagan AM.

    J Pathol. 2012 Nov;228(3):274-85. doi: 10.1002/path.4082. Epub 2012 Sep 26.

    PMID:
    22847733
    [PubMed - indexed for MEDLINE]
    3.

    Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer.

    Roselli M, Fernando RI, Guadagni F, Spila A, Alessandroni J, Palmirotta R, Costarelli L, Litzinger M, Hamilton D, Huang B, Tucker J, Tsang KY, Schlom J, Palena C.

    Clin Cancer Res. 2012 Jul 15;18(14):3868-79. doi: 10.1158/1078-0432.CCR-11-3211. Epub 2012 May 18.

    PMID:
    22611028
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Cancer vaccines targeting the epithelial-mesenchymal transition: tissue distribution of brachyury and other drivers of the mesenchymal-like phenotype of carcinomas.

    Hamilton DH, Litzinger MT, Fernando RI, Huang B, Palena C.

    Semin Oncol. 2012 Jun;39(3):358-66. doi: 10.1053/j.seminoncol.2012.02.005. Review.

    PMID:
    22595058
    [PubMed - indexed for MEDLINE]
    5.

    Activin A promotes hematopoietic fated mesoderm development through upregulation of brachyury in human embryonic stem cells.

    Cerdan C, McIntyre BA, Mechael R, Levadoux-Martin M, Yang J, Lee JB, Bhatia M.

    Stem Cells Dev. 2012 Oct 10;21(15):2866-77. doi: 10.1089/scd.2012.0053. Epub 2012 Jun 13.

    PMID:
    22548442
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells.

    Evans AL, Faial T, Gilchrist MJ, Down T, Vallier L, Pedersen RA, Wardle FC, Smith JC.

    PLoS One. 2012;7(3):e33346. doi: 10.1371/journal.pone.0033346. Epub 2012 Mar 30.

    PMID:
    22479388
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Expression of brachyury in hemangioblastoma: potential use in differential diagnosis.

    Barresi V, Vitarelli E, Branca G, Antonelli M, Giangaspero F, Barresi G.

    Am J Surg Pathol. 2012 Jul;36(7):1052-7. doi: 10.1097/PAS.0b013e31824f4ce3.

    PMID:
    22446946
    [PubMed - indexed for MEDLINE]
    8.

    Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity.

    Pereira LA, Wong MS, Lim SM, Sides A, Stanley EG, Elefanty AG.

    PLoS One. 2011;6(12):e28394. doi: 10.1371/journal.pone.0028394. Epub 2011 Dec 2.

    PMID:
    22164283
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Id1 maintains embryonic stem cell self-renewal by up-regulation of Nanog and repression of Brachyury expression.

    Romero-Lanman EE, Pavlovic S, Amlani B, Chin Y, Benezra R.

    Stem Cells Dev. 2012 Feb 10;21(3):384-93. doi: 10.1089/scd.2011.0428. Epub 2011 Dec 1.

    PMID:
    22013995
    [PubMed - indexed for MEDLINE]
    10.

    P63 does not regulate brachyury expression in human chordomas and osteosarcomas.

    Pillay N, Amary FM, Berisha F, Tirabosco R, Flanagan AM.

    Histopathology. 2011 Nov;59(5):1025-7. doi: 10.1111/j.1365-2559.2011.03973.x. Epub 2011 Oct 18. No abstract available.

    PMID:
    22007675
    [PubMed - indexed for MEDLINE]
    11.

    BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.

    Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA.

    Cell Stem Cell. 2011 Aug 5;9(2):144-55. doi: 10.1016/j.stem.2011.06.015.

    PMID:
    21816365
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.

    Hsu W, Mohyeldin A, Shah SR, ap Rhys CM, Johnson LF, Sedora-Roman NI, Kosztowski TA, Awad OA, McCarthy EF, Loeb DM, Wolinsky JP, Gokaslan ZL, Quiñones-Hinojosa A.

    J Neurosurg. 2011 Oct;115(4):760-9. doi: 10.3171/2011.5.JNS11185. Epub 2011 Jun 24.

    PMID:
    21699479
    [PubMed - indexed for MEDLINE]
    13.

    Induction of MesP1 by Brachyury(T) generates the common multipotent cardiovascular stem cell.

    David R, Jarsch VB, Schwarz F, Nathan P, Gegg M, Lickert H, Franz WM.

    Cardiovasc Res. 2011 Oct 1;92(1):115-22. doi: 10.1093/cvr/cvr158. Epub 2011 Jun 1.

    PMID:
    21632880
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    The cell cycle inhibitor p27Kip¹ controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist.

    Menchón C, Edel MJ, Izpisua Belmonte JC.

    Cell Cycle. 2011 May 1;10(9):1435-47. Epub 2011 May 1.

    PMID:
    21478681
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

    Lyu J, Jho EH, Lu W.

    Cell Res. 2011 Jun;21(6):911-21. doi: 10.1038/cr.2011.47. Epub 2011 Mar 22.

    PMID:
    21423269
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells.

    Sarkar D, Shields B, Davies ML, Müller J, Wakeman JA.

    Int J Cancer. 2012 Jan 15;130(2):328-37. doi: 10.1002/ijc.26029. Epub 2011 May 28.

    PMID:
    21365650
    [PubMed - indexed for MEDLINE]
    17.

    Brachyury expression predicts poor prognosis at early stages of colorectal cancer.

    Kilic N, Feldhaus S, Kilic E, Tennstedt P, Wicklein D, Wasielewski Rv, Viebahn C, Kreipe H, Schumacher U.

    Eur J Cancer. 2011 May;47(7):1080-5. doi: 10.1016/j.ejca.2010.11.015. Epub 2011 Jan 8.

    PMID:
    21220197
    [PubMed - indexed for MEDLINE]
    18.

    Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.

    Presneau N, Shalaby A, Ye H, Pillay N, Halai D, Idowu B, Tirabosco R, Whitwell D, Jacques TS, Kindblom LG, Brüderlein S, Möller P, Leithner A, Liegl B, Amary FM, Athanasou NN, Hogendoorn PC, Mertens F, Szuhai K, Flanagan AM.

    J Pathol. 2011 Feb;223(3):327-35. doi: 10.1002/path.2816. Epub 2010 Nov 24.

    PMID:
    21171078
    [PubMed - indexed for MEDLINE]
    19.

    Specificity of brachyury in the distinction of chordoma from clear cell renal cell carcinoma and germ cell tumors: a study of 305 cases.

    Sangoi AR, Karamchandani J, Lane B, Higgins JP, Rouse RV, Brooks JD, McKenney JK.

    Mod Pathol. 2011 Mar;24(3):425-9. doi: 10.1038/modpathol.2010.196. Epub 2010 Nov 19.

    PMID:
    21102418
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury induction.

    Marikawa Y, Tamashiro DA, Fujita TC, Alarcon VB.

    Stem Cells Dev. 2011 Apr;20(4):621-33. doi: 10.1089/scd.2010.0209. Epub 2011 Jan 8.

    PMID:
    21083502
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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