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Results: 1 to 20 of 34

Select item 232596741.

Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase.

Nakatani Y, Kleffmann T, Linke K, Condon SM, Hinds MG, Day CL.

Biochem J. 2013 Mar 15;450(3):629-38. doi: 10.1042/BJ20121702.

PMID:: 23259674; [PubMed - indexed for MEDLINE]

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Select item 232234282.

Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP.

Gérart S, Sibéril S, Martin E, Lenoir C, Aguilar C, Picard C, Lantz O, Fischer A, Latour S.

Blood. 2013 Jan 24;121(4):614-23. doi: 10.1182/blood-2012-09-456095. Epub 2012 Dec 6.

PMID:: 23223428; [PubMed - indexed for MEDLINE]

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Select item 232225093.

uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway.

Gogineni VR, Gupta R, Nalla AK, Velpula KK, Rao JS.

Cell Death Dis. 2012 Dec 6;3:e439. doi: 10.1038/cddis.2012.170.

PMID:: 23222509; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 231314904.

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes.

Marsh RA, Rao K, Satwani P, Lehmberg K, Müller I, Li D, Kim MO, Fischer A, Latour S, Sedlacek P, Barlogis V, Hamamoto K, Kanegane H, Milanovich S, Margolis DA, Dimmock D, Casper J, Douglas DN, Amrolia PJ, Veys P, Kumar AR, Jordan MB, Bleesing JJ, Filipovich AH.

Blood. 2013 Feb 7;121(6):877-83. doi: 10.1182/blood-2012-06-432500. Epub 2012 Nov 6.

PMID:: 23131490; [PubMed - indexed for MEDLINE]

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Select item 230741975.

Expression of αB-crystallin overrides the anti-apoptotic activity of XIAP.

Lee JS, Kim HY, Jeong NY, Lee SY, Yoon YG, Choi YH, Yan C, Chu IS, Koh H, Park HT, Yoo YH.

Neuro Oncol. 2012 Nov;14(11):1332-45. doi: 10.1093/neuonc/nos247. Epub 2012 Oct 16.

PMID:: 23074197; [PubMed - indexed for MEDLINE]

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Select item 230593866.

XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts.

Doudican NA, Byron SA, Pollock PM, Orlow SJ.

Anticancer Drugs. 2013 Feb;24(2):181-8. doi: 10.1097/CAD.0b013e32835a43f1.

PMID:: 23059386; [PubMed - indexed for MEDLINE]

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Select item 230291067.

A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.

Ling X, Cao S, Cheng Q, Keefe JT, Rustum YM, Li F.

PLoS One. 2012;7(9):e45571. doi: 10.1371/journal.pone.0045571. Epub 2012 Sep 19.

PMID:: 23029106; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 228967098.

The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP.

Fang Y, Yu Y, Hou Q, Zheng X, Zhang M, Zhang D, Li J, Wu XR, Huang C.

J Biol Chem. 2012 Oct 12;287(42):35234-43. doi: 10.1074/jbc.M112.389494. Epub 2012 Aug 15.

PMID:: 22896709; [PubMed - indexed for MEDLINE]

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Select item 228867229.

Hypoxia-induced downregulation of XIAP in trophoblasts mediates apoptosis via interaction with IMUP-2: implications for placental development during pre-eclampsia.

Jeon SY, Lee HJ, Na KH, Cha DH, Kim JK, Park JW, Yoon TK, Kim GJ.

J Cell Biochem. 2013 Jan;114(1):89-98. doi: 10.1002/jcb.24304.

PMID:: 22886722; [PubMed - indexed for MEDLINE]

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Select item 2281589310.

The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2.

Condé C, Rambout X, Lebrun M, Lecat A, Di Valentin E, Dequiedt F, Piette J, Gloire G, Legrand S.

PLoS One. 2012;7(7):e41005. doi: 10.1371/journal.pone.0041005. Epub 2012 Jul 17.

PMID:: 22815893; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2281138711.

Domain organization of XAF1 and the identification and characterization of XIAP(RING) -binding domain of XAF1.

Tse MK, Cho CK, Wong WF, Zou B, Hui SK, Wong BC, Sze KH.

Protein Sci. 2012 Oct;21(10):1418-28. doi: 10.1002/pro.2126. Epub 2012 Sep 17.

PMID:: 22811387; [PubMed - indexed for MEDLINE]

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Select item 2265191712.

High glucose concentration in T1D patients modulates apoptotic protein expression: down regulation of BAX and FAS and up regulation of XIAP.

Valencia E, Codner E, Salas-Pérez F, Pizarro C, Carrasco P E, Arredondo M, Pérez-Bravo F.

Hum Immunol. 2012 Aug;73(8):801-4. doi: 10.1016/j.humimm.2012.04.020. Epub 2012 May 28.

PMID:: 22651917; [PubMed - indexed for MEDLINE]

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Select item 2250852113.

XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells.

Allensworth JL, Aird KM, Aldrich AJ, Batinic-Haberle I, Devi GR.

Mol Cancer Ther. 2012 Jul;11(7):1518-27. doi: 10.1158/1535-7163.MCT-11-0787. Epub 2012 Apr 16.

PMID:: 22508521; [PubMed - indexed for MEDLINE]

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Select item 2249167314.

Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis.

Eschenburg G, Eggert A, Schramm A, Lode HN, Hundsdoerfer P.

Cancer Res. 2012 May 15;72(10):2645-56. doi: 10.1158/0008-5472.CAN-11-4072. Epub 2012 Apr 9.

PMID:: 22491673; [PubMed - indexed for MEDLINE]

Free Article

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Select item 2245956815.

Study of survivin and X-linked inhibitor of apoptosis protein (XIAP) genes in acute myeloid leukemia (AML).

Ibrahim AM, Mansour IM, Wilson MM, Mokhtar DA, Helal AM, Al Wakeel HM.

Lab Hematol. 2012 Mar;18(1):1-10. doi: 10.1532/LH96.09013.

PMID:: 22459568; [PubMed - indexed for MEDLINE]

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Select item 2245124916.

Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer.

Danquah M, Duke CB 3rd, Patil R, Miller DD, Mahato RI.

Pharm Res. 2012 Aug;29(8):2079-91. doi: 10.1007/s11095-012-0737-1. Epub 2012 Mar 27.

PMID:: 22451249; [PubMed - indexed for MEDLINE]

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Select item 2242996517.

Co-expression of XIAP and cyclin D1 complex correlates with a poor prognosis in patients with hepatocellular carcinoma.

Che Y, Ye F, Xu R, Qing H, Wang X, Yin F, Cui M, Burstein D, Jiang B, Zhang DY.

Am J Pathol. 2012 May;180(5):1798-807. doi: 10.1016/j.ajpath.2012.01.016. Epub 2012 Mar 17.

PMID:: 22429965; [PubMed - indexed for MEDLINE]

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Select item 2240361618.

XIAP is a predictor of cisplatin-based chemotherapy response and prognosis for patients with advanced head and neck cancer.

Yang XH, Feng ZE, Yan M, Hanada S, Zuo H, Yang CZ, Han ZG, Guo W, Chen WT, Zhang P.

PLoS One. 2012;7(3):e31601. doi: 10.1371/journal.pone.0031601. Epub 2012 Mar 5.

PMID:: 22403616; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2232536619.

The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.

Ramachandiran S, Cain J, Liao A, He Y, Guo X, Boise LH, Fu H, Ratner L, Khoury HJ, Bernal-Mizrachi L.

Leuk Res. 2012 Jun;36(6):784-90. doi: 10.1016/j.leukres.2011.12.024. Epub 2012 Feb 10.

PMID:: 22325366; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2230496720.

XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling.

Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E.

Mol Cell. 2012 Mar 9;45(5):619-28. doi: 10.1016/j.molcel.2011.12.032. Epub 2012 Feb 1.

PMID:: 22304967; [PubMed - indexed for MEDLINE]

Free PMC Article

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9 free full-text articles in PubMed Central

uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway. [Cell Death Dis. 2012]
uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway.
Gogineni VR, Gupta R, Nalla AK, Velpula KK, Rao JS. Cell Death Dis. 2012 Dec 6; 3:e439. Epub 2012 Dec 6.
A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity. [PLoS One. 2012]
A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.
Ling X, Cao S, Cheng Q, Keefe JT, Rustum YM, Li F. PLoS One. 2012; 7(9):e45571. Epub 2012 Sep 19.
The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. [PLoS One. 2012]
The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2.
Condé C, Rambout X, Lebrun M, Lecat A, Di Valentin E, Dequiedt F, Piette J, Gloire G, Legrand S. PLoS One. 2012; 7(7):e41005. Epub 2012 Jul 17.

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