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    Results: 1 to 20 of 51

    1.

    Protein-protein interactions between the bilirubin-conjugating UDP-glucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing.

    Rouleau M, Collin P, Bellemare J, Harvey M, Guillemette C.

    Biochem J. 2013 Feb 15;450(1):107-14. doi: 10.1042/BJ20121594.

    PMID:
    23148825
    [PubMed - indexed for MEDLINE]

    Related citations

    2.

    Impact of UGT1A1 Gilbert variant on discontinuation of ritonavir-boosted atazanavir in AIDS Clinical Trials Group Study A5202.

    Ribaudo HJ, Daar ES, Tierney C, Morse GD, Mollan K, Sax PE, Fischl MA, Collier AC, Haas DW; DS Clinical Trials Group.

    J Infect Dis. 2013 Feb 1;207(3):420-5. doi: 10.1093/infdis/jis690. Epub 2012 Nov 12.

    PMID:
    23148286
    [PubMed - indexed for MEDLINE]

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    3.

    UDP-glucuronosyltransferase 1A1 (UGT1A1) gene haplotypes and their effect on serum bilirubin concentration in healthy Indian adults.

    D'Silva S, Colah RB, Ghosh K, Mukherjee MB.

    Gene. 2013 Jan 15;513(1):36-9. doi: 10.1016/j.gene.2012.10.081. Epub 2012 Nov 9.

    PMID:
    23147267
    [PubMed - indexed for MEDLINE]

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    4.

    Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer.

    Takahara N, Nakai Y, Isayama H, Sasaki T, Satoh Y, Takai D, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Mohri D, Kawakubo K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tada M, Yatomi Y, Koike K.

    Cancer Chemother Pharmacol. 2013 Jan;71(1):85-92. doi: 10.1007/s00280-012-1981-0. Epub 2012 Sep 29.

    PMID:
    23053265
    [PubMed - indexed for MEDLINE]

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    5.

    Comprehensive analysis of UGT1A1 genetic polymorphisms in Chinese Tibetan and Han populations.

    Zhang X, Meng X, Wang Y, Yan W, Yang J.

    Biochem Genet. 2012 Dec;50(11-12):967-77. doi: 10.1007/s10528-012-9536-y. Epub 2012 Sep 16.

    PMID:
    22983686
    [PubMed - indexed for MEDLINE]

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    6.

    Polymorphisms of UGT1A1*6, UGT1A1*27 & UGT1A1*28 in three major ethnic groups from Malaysia.

    Teh LK, Hashim H, Zakaria ZA, Salleh MZ.

    Indian J Med Res. 2012 Aug;136(2):249-59.

    PMID:
    22960892
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    7.

    Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.

    Sugatani J, Uchida T, Kurosawa M, Yamaguchi M, Yamazaki Y, Ikari A, Miwa M.

    Drug Metab Dispos. 2012 Oct;40(10):2031-40. doi: 10.1124/dmd.112.046748. Epub 2012 Jul 24.

    PMID:
    22829544
    [PubMed - indexed for MEDLINE]

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    8.

    Wayward effect of polymorphism (TA)8 in the promoter region of UGT1A1 gene in a Mexican family.

    Tintos-Hernández JA, Perea FJ, Ibarra B, Figuera LE.

    West Indian Med J. 2012 Jan;61(1):81-3.

    PMID:
    22808571
    [PubMed - indexed for MEDLINE]

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    9.

    Effects of statin treatments and polymorphisms in UGT1A1 and SLCO1B1 on serum bilirubin levels in Chinese patients with hypercholesterolaemia.

    Hu M, Tomlinson B.

    Atherosclerosis. 2012 Aug;223(2):427-32. doi: 10.1016/j.atherosclerosis.2012.06.002. Epub 2012 Jun 13.

    PMID:
    22749334
    [PubMed - indexed for MEDLINE]

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    10.

    UGT1A1 genotype in a white boy with Crigler-Najjar syndrome type 2.

    Peña L, Pico M, Rosatelli C, Meloni A, Del Río E, Tizzano EF, Baiget M.

    J Pediatr Gastroenterol Nutr. 2012 Nov;55(5):e136-7. doi: 10.1097/MPG.0b013e318234ecd9. No abstract available.

    PMID:
    22722682
    [PubMed - indexed for MEDLINE]

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    11.

    Impact of the UGT1A1*28 allele on response to irinotecan: a systematic review and meta-analysis.

    Dias MM, McKinnon RA, Sorich MJ.

    Pharmacogenomics. 2012 Jun;13(8):889-99. doi: 10.2217/pgs.12.68.

    PMID:
    22676194
    [PubMed - indexed for MEDLINE]

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    12.

    Switching to unboosted atazanavir reduces bilirubin and triglycerides without compromising treatment efficacy in UGT1A1*28 polymorphism carriers.

    Ferraris L, Viganò O, Peri A, Tarkowski M, Milani G, Bonora S, Adorni F, Gervasoni C, Clementi E, Di Perri G, Galli M, Riva A.

    J Antimicrob Chemother. 2012 Sep;67(9):2236-42. doi: 10.1093/jac/dks175. Epub 2012 Jun 2.

    PMID:
    22661571
    [PubMed - indexed for MEDLINE]

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    13.

    UGT1A1, SLCO1B1, and SLCO1B3 polymorphisms vs. neonatal hyperbilirubinemia: is there an association?

    Alencastro de Azevedo L, Reverbel da Silveira T, Carvalho CG, Martins de Castro S, Giugliani R, Matte U.

    Pediatr Res. 2012 Aug;72(2):169-73.

    PMID:
    22580719
    [PubMed - indexed for MEDLINE]

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    14.

    Glucuronidation of the second-generation antipsychotic clozapine and its active metabolite N-desmethylclozapine. Potential importance of the UGT1A1 A(TA)₇TAA and UGT1A4 L48V polymorphisms.

    Erickson-Ridout KK, Sun D, Lazarus P.

    Pharmacogenet Genomics. 2012 Aug;22(8):561-76. doi: 10.1097/FPC.0b013e328354026b.

    PMID:
    22565219
    [PubMed - indexed for MEDLINE]

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    15.

    Promoter length polymorphism in UGT1A1 and the risk of sporadic colorectal cancer.

    Bajro MH, Josifovski T, Panovski M, Jankulovski N, Nestorovska AK, Matevska N, Petrusevska N, Dimovski AJ.

    Cancer Genet. 2012 Apr;205(4):163-7. doi: 10.1016/j.cancergen.2012.01.015.

    PMID:
    22559977
    [PubMed - indexed for MEDLINE]

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    16.

    A Phase II study of clinical outcomes of 3-week cycles of irinotecan and S-1 in patients with previously untreated metastatic colorectal cancer: influence of the UGT1A1 and CYP2A6 polymorphisms on clinical activity.

    Choi YH, Kim TW, Kim KP, Lee SS, Hong YS, Ryu MH, Lee JL, Chang HM, Ryoo BY, Kim HS, Shin JG, Kang YK.

    Oncology. 2012;82(5):290-7. doi: 10.1159/000337989. Epub 2012 Apr 28.

    PMID:
    22555197
    [PubMed - indexed for MEDLINE]

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    17.

    Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

    Montenegro-Miranda PS, Sneitz N, de Waart DR, Ten Bloemendaal L, Duijst S, de Knegt RJ, Beuers U, Finel M, Bosma PJ.

    Biochim Biophys Acta. 2012 Aug;1822(8):1223-9. doi: 10.1016/j.bbadis.2012.04.013. Epub 2012 Apr 21.

    PMID:
    22546842
    [PubMed - indexed for MEDLINE]

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    18.

    Phase II and UGT1A1 genotype study of irinotecan dose escalation as salvage therapy for advanced gastric cancer.

    Jo JC, Lee JL, Ryu MH, Chang HM, Kim M, Lee HJ, Kim HS, Shin JG, Kim TW, Kang YK.

    Br J Cancer. 2012 May 8;106(10):1591-7. doi: 10.1038/bjc.2012.143. Epub 2012 Apr 19.

    PMID:
    22516947
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    19.

    A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

    Jylhävä J, Lyytikäinen LP, Kähönen M, Hutri-Kähönen N, Kettunen J, Viikari J, Raitakari OT, Lehtimäki T, Hurme M.

    PLoS One. 2012;7(4):e35426. doi: 10.1371/journal.pone.0035426. Epub 2012 Apr 12.

    PMID:
    22511988
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    20.

    Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma.

    Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H.

    Leuk Lymphoma. 2012 Oct;53(10):1934-44. doi: 10.3109/10428194.2012.682307. Epub 2012 May 22.

    PMID:
    22475179
    [PubMed - indexed for MEDLINE]

    Related citations

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