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Results: 1 to 20 of 97

1.

The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.

Hooli BV, Parrado AR, Mullin K, Yip WK, Liu T, Roehr JT, Qiao D, Jessen F, Peters O, Becker T, Ramirez A, Lange C, Bertram L, Tanzi RE.

Neurology. 2014 Oct 7;83(15):1353-8. doi: 10.1212/WNL.0000000000000855. Epub 2014 Sep 3.

PMID:
25186855
2.

3-O-sulfo-β-D-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5.

Phongsisay V, Iizasa E, Hara H, Yamasaki S.

Mol Immunol. 2015 Feb;63(2):595-9. doi: 10.1016/j.molimm.2014.07.023. Epub 2014 Aug 27.

PMID:
25172093
3.

Campylobacter jejuni targets immunoglobulin-like receptor LMIR5.

Phongsisay V.

Mol Immunol. 2015 Feb;63(2):574-8. doi: 10.1016/j.molimm.2014.07.024. Epub 2014 Aug 27.

PMID:
25172092
4.

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C.

Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.

PMID:
24990881
5.

Homozygous TREM2 mutation in a family with atypical frontotemporal dementia.

Le Ber I, De Septenville A, Guerreiro R, Bras J, Camuzat A, Caroppo P, Lattante S, Couarch P, Kabashi E, Bouya-Ahmed K, Dubois B, Brice A.

Neurobiol Aging. 2014 Oct;35(10):2419.e23-5. doi: 10.1016/j.neurobiolaging.2014.04.010. Epub 2014 Apr 18.

6.

LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.

Satoh J, Motohashi N, Kino Y, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K.

Orphanet J Rare Dis. 2014 May 1;9:68. doi: 10.1186/1750-1172-9-68.

7.

Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China.

Jiao B, Liu X, Tang B, Hou L, Zhou L, Zhang F, Zhou Y, Guo J, Yan X, Shen L.

Neurobiol Aging. 2014 Oct;35(10):2422.e9-2422.e11. doi: 10.1016/j.neurobiolaging.2014.04.025. Epub 2014 May 1.

PMID:
24866402
8.

Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population.

Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Furukawa K, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Nishizawa M, Suga M, Kawase Y, Akatsu H, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Yamaguchi H, Akazawa K, Kanazawa I, Ihara Y, Ikeuchi T, Kuwano R.

J Alzheimers Dis. 2014;41(4):1031-8. doi: 10.3233/JAD-140225.

PMID:
24762945
9.

The genetics of Alzheimer's disease.

Bagyinszky E, Youn YC, An SS, Kim S.

Clin Interv Aging. 2014 Apr 1;9:535-51. doi: 10.2147/CIA.S51571. eCollection 2014. Review.

10.

Evidence of trem2 variant associated with triple risk of Alzheimer's disease.

Abduljaleel Z, Al-Allaf FA, Khan W, Athar M, Shahzad N, Taher MM, Elrobh M, Alanazi MS, El-Huneidi W.

PLoS One. 2014 Mar 24;9(3):e92648. doi: 10.1371/journal.pone.0092648. eCollection 2014.

11.

C9ORF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation.

Solje E, Hartikainen P, Valori M, Vanninen R, Tiihonen J, Hakola P, Tienari PJ, Remes AM.

Neurobiol Aging. 2014 Jul;35(7):1780.e13-7. doi: 10.1016/j.neurobiolaging.2014.01.149. Epub 2014 Feb 5.

PMID:
24612676
12.

Triggering receptor expressed on myeloid cells 2 variants are rare in Parkinson's disease in a Han Chinese cohort.

Feng SJ, Nie K, Gan R, Huang J, Zhang YW, Wang LM, Zhao JH, Tang HM, Gao L, Zhu RM, Duan ZP, Zhang YH, Wang LJ.

Neurobiol Aging. 2014 Jul;35(7):1780.e11-2. doi: 10.1016/j.neurobiolaging.2014.01.142. Epub 2014 Feb 5.

PMID:
24602511
13.

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis.

Cady J, Koval ED, Benitez BA, Zaidman C, Jockel-Balsarotti J, Allred P, Baloh RH, Ravits J, Simpson E, Appel SH, Pestronk A, Goate AM, Miller TM, Cruchaga C, Harms MB.

JAMA Neurol. 2014 Apr;71(4):449-53. doi: 10.1001/jamaneurol.2013.6237.

PMID:
24535663
14.

Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases.

Kober DL, Wanhainen KM, Johnson BM, Randolph DT, Holtzman MJ, Brett TJ.

Protein Expr Purif. 2014 Apr;96:32-8. doi: 10.1016/j.pep.2014.01.015. Epub 2014 Feb 7.

PMID:
24508568
15.

Molecular characterization of antigen-peptide pulsed dendritic cells: immature dendritic cells develop a distinct molecular profile when pulsed with antigen peptide.

Yang AX, Chong N, Jiang Y, Catalano J, Puri RK, Khleif SN.

PLoS One. 2014 Jan 27;9(1):e86306. doi: 10.1371/journal.pone.0086306. eCollection 2014.

16.

Missense variant in TREML2 protects against Alzheimer's disease.

Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; 3C Study Group; EADI consortium; Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Disease Neuroimaging Initiative (ADNI); GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C.

Neurobiol Aging. 2014 Jun;35(6):1510.e19-26. doi: 10.1016/j.neurobiolaging.2013.12.010. Epub 2013 Dec 21.

17.

Investigation of triggering receptor expressed on myeloid cells 2 variant in the Wisconsin Registry for Alzheimer's Prevention.

Engelman CD, Koscik RL, Jonaitis EM, Hermann BP, La Rue A, Sager MA.

Neurobiol Aging. 2014 Jun;35(6):1252-4. doi: 10.1016/j.neurobiolaging.2013.11.013. Epub 2013 Nov 20.

PMID:
24378087
18.

TREM2 and the neuroimmunology of Alzheimer's disease.

Hickman SE, El Khoury J.

Biochem Pharmacol. 2014 Apr 15;88(4):495-8. doi: 10.1016/j.bcp.2013.11.021. Epub 2013 Dec 16. Review.

PMID:
24355566
19.

Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseases.

Pelham CJ, Agrawal DK.

Expert Rev Clin Immunol. 2014 Feb;10(2):243-56. doi: 10.1586/1744666X.2014.866519. Epub 2013 Dec 10. Review.

PMID:
24325404
20.

Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer's disease in Han Chinese individuals.

Yu JT, Jiang T, Wang YL, Wang HF, Zhang W, Hu N, Tan L, Sun L, Tan MS, Zhu XC, Tan L.

Neurobiol Aging. 2014 Apr;35(4):937.e1-3. doi: 10.1016/j.neurobiolaging.2013.10.075. Epub 2013 Oct 11.

PMID:
24184202
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