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    Results: 1 to 20 of 168

    1.

    Notch pathway activation targets AML-initiating cell homeostasis and differentiation.

    Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, Aifantis I.

    J Exp Med. 2013 Feb 11;210(2):301-19. doi: 10.1084/jem.20121484. Epub 2013 Jan 28.

    PMID:
    23359070
    [PubMed - indexed for MEDLINE]
    2.

    TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.

    Deplus R, Delatte B, Schwinn MK, Defrance M, Méndez J, Murphy N, Dawson MA, Volkmar M, Putmans P, Calonne E, Shih AH, Levine RL, Bernard O, Mercher T, Solary E, Urh M, Daniels DL, Fuks F.

    EMBO J. 2013 Mar 6;32(5):645-55. doi: 10.1038/emboj.2012.357. Epub 2013 Jan 25.

    PMID:
    23353889
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Clonal architecture of chronic myelomonocytic leukemias.

    Itzykson R, Kosmider O, Renneville A, Morabito M, Preudhomme C, Berthon C, Adès L, Fenaux P, Platzbecker U, Gagey O, Rameau P, Meurice G, Oréar C, Delhommeau F, Bernard OA, Fontenay M, Vainchenker W, Droin N, Solary E.

    Blood. 2013 Mar 21;121(12):2186-98. doi: 10.1182/blood-2012-06-440347. Epub 2013 Jan 14.

    PMID:
    23319568
    [PubMed - indexed for MEDLINE]
    4.

    TET2 promotes histone O-GlcNAcylation during gene transcription.

    Chen Q, Chen Y, Bian C, Fujiki R, Yu X.

    Nature. 2013 Jan 24;493(7433):561-4. doi: 10.1038/nature11742. Epub 2012 Dec 9.

    PMID:
    23222540
    [PubMed - indexed for MEDLINE]
    5.

    TET2, ASXL1 and EZH2 mutations in Chinese with myelodysplastic syndromes.

    Wang J, Ai X, Gale RP, Xu Z, Qin T, Fang L, Zhang H, Pan L, Hu N, Zhang Y, Xiao Z.

    Leuk Res. 2013 Mar;37(3):305-11. doi: 10.1016/j.leukres.2012.10.004. Epub 2012 Oct 23.

    PMID:
    23099237
    [PubMed - indexed for MEDLINE]
    6.

    In aggressive forms of mastocytosis, TET2 loss cooperates with c-KITD816V to transform mast cells.

    Soucie E, Hanssens K, Mercher T, Georgin-Lavialle S, Damaj G, Livideanu C, Chandesris MO, Acin Y, Létard S, de Sepulveda P, Hermine O, Bernard OA, Dubreuil P.

    Blood. 2012 Dec 6;120(24):4846-9. doi: 10.1182/blood-2011-12-397588. Epub 2012 Oct 16.

    PMID:
    23074272
    [PubMed - indexed for MEDLINE]
    7.

    Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.

    Nischal S, Bhattacharyya S, Christopeit M, Yu Y, Zhou L, Bhagat TD, Sohal D, Will B, Mo Y, Suzuki M, Pardanani A, McDevitt M, Maciejewski JP, Melnick AM, Greally JM, Steidl U, Moliterno A, Verma A.

    Cancer Res. 2013 Feb 1;73(3):1076-85. doi: 10.1158/0008-5472.CAN-12-0735. Epub 2012 Oct 11.

    PMID:
    23066032
    [PubMed - indexed for MEDLINE]
    8.

    Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.

    Arioka Y, Watanabe A, Saito K, Yamada Y.

    PLoS One. 2012;7(9):e45031. doi: 10.1371/journal.pone.0045031. Epub 2012 Sep 17.

    PMID:
    23028748
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Current outlook on molecular pathogenesis and treatment of myeloproliferative neoplasms.

    Tibes R, Bogenberger JM, Benson KL, Mesa RA.

    Mol Diagn Ther. 2012 Oct;16(5):269-83. doi: 10.1007/s40291-012-0006-3. Review.

    PMID:
    23023734
    [PubMed - indexed for MEDLINE]
    10.

    Epigenetic alterations in hematopoietic malignancies.

    Chung YR, Schatoff E, Abdel-Wahab O.

    Int J Hematol. 2012 Oct;96(4):413-27. doi: 10.1007/s12185-012-1181-z. Epub 2012 Sep 27. Review.

    PMID:
    23015417
    [PubMed - indexed for MEDLINE]
    11.

    Activating CBL mutations are associated with a distinct MDS/MPN phenotype.

    Schwaab J, Ernst T, Erben P, Rinke J, Schnittger S, Ströbel P, Metzgeroth G, Mossner M, Haferlach T, Cross NC, Hochhaus A, Hofmann WK, Reiter A.

    Ann Hematol. 2012 Nov;91(11):1713-20. doi: 10.1007/s00277-012-1521-3. Epub 2012 Aug 10.

    PMID:
    23010802
    [PubMed - indexed for MEDLINE]
    12.

    Role of TET2 and ASXL1 mutations in the pathogenesis of myeloproliferative neoplasms.

    Abdel-Wahab O, Tefferi A, Levine RL.

    Hematol Oncol Clin North Am. 2012 Oct;26(5):1053-64. doi: 10.1016/j.hoc.2012.07.006. Epub 2012 Aug 21. Review.

    PMID:
    23009937
    [PubMed - indexed for MEDLINE]
    13.

    Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.

    Busque L, Patel JP, Figueroa ME, Vasanthakumar A, Provost S, Hamilou Z, Mollica L, Li J, Viale A, Heguy A, Hassimi M, Socci N, Bhatt PK, Gonen M, Mason CE, Melnick A, Godley LA, Brennan CW, Abdel-Wahab O, Levine RL.

    Nat Genet. 2012 Nov;44(11):1179-81. doi: 10.1038/ng.2413. Epub 2012 Sep 23.

    PMID:
    23001125
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells.

    Kallin EM, Rodríguez-Ubreva J, Christensen J, Cimmino L, Aifantis I, Helin K, Ballestar E, Graf T.

    Mol Cell. 2012 Oct 26;48(2):266-76. doi: 10.1016/j.molcel.2012.08.007. Epub 2012 Sep 13.

    PMID:
    22981865
    [PubMed - indexed for MEDLINE]
    15.

    Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

    Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG.

    Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033.

    PMID:
    22980977
    [PubMed - indexed for MEDLINE]
    16.

    Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing.

    Dolnik A, Engelmann JC, Scharfenberger-Schmeer M, Mauch J, Kelkenberg-Schade S, Haldemann B, Fries T, Krönke J, Kühn MW, Paschka P, Kayser S, Wolf S, Gaidzik VI, Schlenk RF, Rücker FG, Döhner H, Lottaz C, Döhner K, Bullinger L.

    Blood. 2012 Nov 1;120(18):e83-92. doi: 10.1182/blood-2011-12-401471. Epub 2012 Sep 13.

    PMID:
    22976956
    [PubMed - indexed for MEDLINE]
    17.

    Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients.

    Dong E, Gavin DP, Chen Y, Davis J.

    Transl Psychiatry. 2012 Sep 4;2:e159. doi: 10.1038/tp.2012.86.

    PMID:
    22948384
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

    Jan M, Snyder TM, Corces-Zimmerman MR, Vyas P, Weissman IL, Quake SR, Majeti R.

    Sci Transl Med. 2012 Aug 29;4(149):149ra118. doi: 10.1126/scitranslmed.3004315.

    PMID:
    22932223
    [PubMed - indexed for MEDLINE]
    19.

    SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML).

    Meggendorfer M, Roller A, Haferlach T, Eder C, Dicker F, Grossmann V, Kohlmann A, Alpermann T, Yoshida K, Ogawa S, Koeffler HP, Kern W, Haferlach C, Schnittger S.

    Blood. 2012 Oct 11;120(15):3080-8. doi: 10.1182/blood-2012-01-404863. Epub 2012 Aug 23.

    PMID:
    22919025
    [PubMed - indexed for MEDLINE]
    20.

    IDH mutations in acute myeloid leukemia.

    Rakheja D, Konoplev S, Medeiros LJ, Chen W.

    Hum Pathol. 2012 Oct;43(10):1541-51. doi: 10.1016/j.humpath.2012.05.003. Epub 2012 Aug 20. Review.

    PMID:
    22917530
    [PubMed - indexed for MEDLINE]

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