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    Results: 1 to 20 of 37

    1.

    Evidence for downregulation of the negative regulator SPRED2 in clinical prostate cancer.

    Kachroo N, Valencia T, Warren AY, Gnanapragasam VJ.

    Br J Cancer. 2013 Feb 19;108(3):597-601. doi: 10.1038/bjc.2012.507. Epub 2012 Nov 20.

    PMID:
    23169297
    [PubMed - indexed for MEDLINE]
    2.

    Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis.

    Zhou T, Zhang W, Sweiss NJ, Chen ES, Moller DR, Knox KS, Ma SF, Wade MS, Noth I, Machado RF, Garcia JG.

    PLoS One. 2012;7(9):e44818. doi: 10.1371/journal.pone.0044818. Epub 2012 Sep 12.

    PMID:
    22984568
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    SPRED proteins provide a NF-ty link to Ras suppression.

    McClatchey AI, Cichowski K.

    Genes Dev. 2012 Jul 15;26(14):1515-9. doi: 10.1101/gad.197434.112.

    PMID:
    22802525
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Review and update of SPRED1 mutations causing Legius syndrome.

    Brems H, Pasmant E, Van Minkelen R, Wimmer K, Upadhyaya M, Legius E, Messiaen L.

    Hum Mutat. 2012 Nov;33(11):1538-46. doi: 10.1002/humu.22152. Epub 2012 Aug 1. Review.

    PMID:
    22753041
    [PubMed - indexed for MEDLINE]
    5.

    A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.

    Stowe IB, Mercado EL, Stowe TR, Bell EL, Oses-Prieto JA, Hernández H, Burlingame AL, McCormick F.

    Genes Dev. 2012 Jul 1;26(13):1421-6. doi: 10.1101/gad.190876.112.

    PMID:
    22751498
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1.

    Meng S, Cao JT, Zhang B, Zhou Q, Shen CX, Wang CQ.

    J Mol Cell Cardiol. 2012 Jul;53(1):64-72. doi: 10.1016/j.yjmcc.2012.04.003. Epub 2012 Apr 16.

    PMID:
    22525256
    [PubMed - indexed for MEDLINE]
    7.

    Café-au-lait macules and intertriginous freckling in piebaldism: clinical overlap with neurofibromatosis type 1 and Legius syndrome.

    Stevens CA, Chiang PW, Messiaen LM.

    Am J Med Genet A. 2012 May;158A(5):1195-9. doi: 10.1002/ajmg.a.35297. Epub 2012 Mar 21.

    PMID:
    22438235
    [PubMed - indexed for MEDLINE]
    8.

    Spectrum of mutations in Noonan syndrome and their correlation with phenotypes.

    Lee BH, Kim JM, Jin HY, Kim GH, Choi JH, Yoo HW.

    J Pediatr. 2011 Dec;159(6):1029-35. doi: 10.1016/j.jpeds.2011.05.024. Epub 2011 Jul 23.

    PMID:
    21784453
    [PubMed - indexed for MEDLINE]
    9.

    miR126 positively regulates mast cell proliferation and cytokine production through suppressing Spred1.

    Ishizaki T, Tamiya T, Taniguchi K, Morita R, Kato R, Okamoto F, Saeki K, Nomura M, Nojima Y, Yoshimura A.

    Genes Cells. 2011 Jul;16(7):803-14. doi: 10.1111/j.1365-2443.2011.01529.x. Epub 2011 Jun 13.

    PMID:
    21668589
    [PubMed - indexed for MEDLINE]
    10.

    Identification of five novel SPRED1 germline mutations in Legius syndrome.

    Laycock-van Spyk S, Jim HP, Thomas L, Spurlock G, Fares L, Palmer-Smith S, Kini U, Saggar A, Patton M, Mautner V, Pilz DT, Upadhyaya M.

    Clin Genet. 2011 Jul;80(1):93-6. doi: 10.1111/j.1399-0004.2010.01618.x. No abstract available.

    PMID:
    21649642
    [PubMed - indexed for MEDLINE]
    11.

    Interaction of the receptor FGFRL1 with the negative regulator Spred1.

    Zhuang L, Villiger P, Trueb B.

    Cell Signal. 2011 Sep;23(9):1496-504. doi: 10.1016/j.cellsig.2011.05.006. Epub 2011 May 16.

    PMID:
    21616146
    [PubMed - indexed for MEDLINE]
    12.

    Identification of SPRED1 deletions using RT-PCR, multiplex ligation-dependent probe amplification and quantitative PCR.

    Spencer E, Davis J, Mikhail F, Fu C, Vijzelaar R, Zackai EH, Feret H, Meyn MS, Shugar A, Bellus G, Kocsis K, Kivirikko S, Pöyhönen M, Messiaen L.

    Am J Med Genet A. 2011 Jun;155A(6):1352-9. doi: 10.1002/ajmg.a.33894. Epub 2011 May 5.

    PMID:
    21548021
    [PubMed - indexed for MEDLINE]
    13.

    Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain-containing protein (SPRED1), a tyrosine-protein phosphatase non-receptor type 11 (SHP2) substrate in the Ras/extracellular signal-regulated kinase (ERK) pathway.

    Quintanar-Audelo M, Yusoff P, Sinniah S, Chandramouli S, Guy GR.

    J Biol Chem. 2011 Jul 1;286(26):23102-12. doi: 10.1074/jbc.M110.212662. Epub 2011 Apr 29.

    PMID:
    21531714
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    KITLG mutations cause familial progressive hyper- and hypopigmentation.

    Amyere M, Vogt T, Hoo J, Brandrup F, Bygum A, Boon L, Vikkula M.

    J Invest Dermatol. 2011 Jun;131(6):1234-9. doi: 10.1038/jid.2011.29. Epub 2011 Mar 3.

    PMID:
    21368769
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids.

    García-Domínguez CA, Martínez N, Gragera T, Pérez-Rodríguez A, Retana D, León G, Sánchez A, Oliva JL, Pérez-Sala D, Rojas JM.

    PLoS One. 2011 Feb 22;6(2):e16787. doi: 10.1371/journal.pone.0016787.

    PMID:
    21364986
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Familial multiple lipomatosis with clear autosomal dominant inheritance and onset in early adolescence.

    Lee CH, Spence RA, Upadhyaya M, Morrison PJ.

    BMJ Case Rep. 2011 Feb 17;2011. doi:pii: bcr1020103395. 10.1136/bcr.10.2010.3395.

    PMID:
    22707495
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Legius syndrome in fourteen families.

    Denayer E, Chmara M, Brems H, Kievit AM, van Bever Y, Van den Ouweland AM, Van Minkelen R, de Goede-Bolder A, Oostenbrink R, Lakeman P, Beert E, Ishizaki T, Mori T, Keymolen K, Van den Ende J, Mangold E, Peltonen S, Brice G, Rankin J, Van Spaendonck-Zwarts KY, Yoshimura A, Legius E.

    Hum Mutat. 2011 Jan;32(1):E1985-98. doi: 10.1002/humu.21404.

    PMID:
    21089071
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability.

    Pepini T, Gorbunova EE, Gavrilovskaya IN, Mackow JE, Mackow ER.

    J Virol. 2010 Nov;84(22):11929-36. doi: 10.1128/JVI.01658-10. Epub 2010 Sep 15.

    PMID:
    20844033
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions.

    Li D, Jackson RA, Yusoff P, Guy GR.

    J Biol Chem. 2010 Nov 12;285(46):35374-85. doi: 10.1074/jbc.M110.148445. Epub 2010 Aug 24.

    PMID:
    20736167
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    NF1 exon 22 analysis of individuals with the clinical diagnosis of neurofibromatosis type 1.

    Muram-Zborovski TM, Vaughn CP, Viskochil DH, Hanson H, Mao R, Stevenson DA.

    Am J Med Genet A. 2010 Aug;152A(8):1973-8. doi: 10.1002/ajmg.a.33525.

    PMID:
    20602485
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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