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    Results: 1 to 20 of 35

    1.

    Endoplasmic reticulum dysfunction in neurological disease.

    Roussel BD, Kruppa AJ, Miranda E, Crowther DC, Lomas DA, Marciniak SJ.

    Lancet Neurol. 2013 Jan;12(1):105-18. doi: 10.1016/S1474-4422(12)70238-7. Review.

    PMID:
    23237905
    [PubMed - indexed for MEDLINE]
    2.

    The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.

    Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL.

    Brain. 2012 Nov;135(Pt 11):3251-64. doi: 10.1093/brain/aws178. Epub 2012 Jul 20.

    PMID:
    22822039
    [PubMed - indexed for MEDLINE]
    3.

    Expression of neuroserpin, a selective inhibitor of tissue-type plasminogen activator in the human skin.

    Chéret J, Lebonvallet N, Misery L, Le Gall-Ianotto C.

    Exp Dermatol. 2012 Sep;21(9):710-1. doi: 10.1111/j.1600-0625.2012.01541.x. Epub 2012 Jun 29.

    PMID:
    22742704
    [PubMed - indexed for MEDLINE]
    4.

    MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer.

    Yamanaka S, Olaru AV, An F, Luvsanjav D, Jin Z, Agarwal R, Tomuleasa C, Popescu I, Alexandrescu S, Dima S, Chivu-Economescu M, Montgomery EA, Torbenson M, Meltzer SJ, Selaru FM.

    Dig Liver Dis. 2012 Jul;44(7):589-96. doi: 10.1016/j.dld.2012.02.016. Epub 2012 Mar 28.

    PMID:
    22464652
    [PubMed - indexed for MEDLINE]
    5.

    The tempered polymerization of human neuroserpin.

    Noto R, Santangelo MG, Ricagno S, Mangione MR, Levantino M, Pezzullo M, Martorana V, Cupane A, Bolognesi M, Manno M.

    PLoS One. 2012;7(3):e32444. doi: 10.1371/journal.pone.0032444. Epub 2012 Mar 6.

    PMID:
    22412873
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    The serpinopathies studying serpin polymerization in vivo.

    Irving JA, Ekeowa UI, Belorgey D, Haq I, Gooptu B, Miranda E, Pérez J, Roussel BD, Ordóñez A, Dalton LE, Thomas SE, Marciniak SJ, Parfrey H, Chilvers ER, Teckman JH, Alam S, Mahadeva R, Rashid ST, Vallier L, Lomas DA.

    Methods Enzymol. 2011;501:421-66. doi: 10.1016/B978-0-12-385950-1.00018-3.

    PMID:
    22078544
    [PubMed - indexed for MEDLINE]
    7.

    Determining serpin conformational distributions with single molecule fluorescence.

    Mushero N, Gershenson A.

    Methods Enzymol. 2011;501:351-77. doi: 10.1016/B978-0-12-385950-1.00016-X.

    PMID:
    22078542
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    On the molecular structure of human neuroserpin polymers.

    Santangelo MG, Noto R, Levantino M, Cupane A, Ricagno S, Pezzullo M, Bolognesi M, Mangione MR, Martorana V, Manno M.

    Proteins. 2012 Jan;80(1):8-13. doi: 10.1002/prot.23197. Epub 2011 Nov 9.

    PMID:
    22072549
    [PubMed - indexed for MEDLINE]
    9.

    Local conformational flexibility provides a basis for facile polymer formation in human neuroserpin.

    Sarkar A, Zhou C, Meklemburg R, Wintrode PL.

    Biophys J. 2011 Oct 5;101(7):1758-65. doi: 10.1016/j.bpj.2011.08.037.

    PMID:
    21961602
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Activators and inhibitors of the plasminogen system in Alzheimer's disease.

    Barker R, Kehoe PG, Love S.

    J Cell Mol Med. 2012 Apr;16(4):865-76. doi: 10.1111/j.1582-4934.2011.01394.x.

    PMID:
    21790972
    [PubMed - indexed for MEDLINE]
    11.

    Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer's disease transgenic mouse model.

    Fabbro S, Schaller K, Seeds NW.

    J Neurochem. 2011 Sep;118(5):928-38. doi: 10.1111/j.1471-4159.2011.07359.x. Epub 2011 Jul 18.

    PMID:
    21689108
    [PubMed - indexed for MEDLINE]
    12.

    Unravelling the twists and turns of the serpinopathies.

    Roussel BD, Irving JA, Ekeowa UI, Belorgey D, Haq I, Ordóñez A, Kruppa AJ, Duvoix A, Rashid ST, Crowther DC, Marciniak SJ, Lomas DA.

    FEBS J. 2011 Oct;278(20):3859-67. doi: 10.1111/j.1742-4658.2011.08201.x. Epub 2011 Jun 20. Review.

    PMID:
    21624056
    [PubMed - indexed for MEDLINE]
    13.

    Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke.

    Rodríguez-González R, Sobrino T, Rodríguez-Yáñez M, Millán M, Brea D, Miranda E, Moldes O, Pérez J, Lomas DA, Leira R, Dávalos A, Castillo J.

    J Transl Med. 2011 May 11;9:58. doi: 10.1186/1479-5876-9-58.

    PMID:
    21569344
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    The endoplasmic reticulum (ER)-associated degradation system regulates aggregation and degradation of mutant neuroserpin.

    Ying Z, Wang H, Fan H, Wang G.

    J Biol Chem. 2011 Jun 10;286(23):20835-44. doi: 10.1074/jbc.M110.200808. Epub 2011 Apr 20.

    PMID:
    21507957
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    No evidence for an association between genetic variation at the SERPINI1 locus and ischemic stroke.

    Tjärnlund-Wolf A, Olsson S, Jood K, Blomstrand C, Jern C.

    J Neurol. 2011 Oct;258(10):1885-7. doi: 10.1007/s00415-011-6022-0. Epub 2011 Apr 13. No abstract available.

    PMID:
    21487809
    [PubMed - indexed for MEDLINE]
    16.

    Encephalopathy with neuroserpin inclusion bodies presenting as progressive myoclonus epilepsy and associated with a novel mutation in the Proteinase Inhibitor 12 gene.

    Hagen MC, Murrell JR, Delisle MB, Andermann E, Andermann F, Guiot MC, Ghetti B.

    Brain Pathol. 2011 Sep;21(5):575-82. doi: 10.1111/j.1750-3639.2011.00481.x. Epub 2011 Mar 24.

    PMID:
    21435071
    [PubMed - indexed for MEDLINE]
    17.

    The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome.

    Rodríguez-González R, Millán M, Sobrino T, Miranda E, Brea D, de la Ossa NP, Blanco M, Perez J, Dorado L, Castellanos M, Lomas DA, Moro MA, Dávalos A, Castillo J.

    Thromb Haemost. 2011 Mar;105(3):421-9. doi: 10.1160/TH10-09-0621. Epub 2010 Dec 21.

    PMID:
    21174006
    [PubMed - indexed for MEDLINE]
    18.

    Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA.

    Rodríguez-González R, Agulla J, Pérez-Mato M, Sobrino T, Castillo J.

    Neurochem Int. 2011 Feb;58(3):337-43. doi: 10.1016/j.neuint.2010.12.006. Epub 2010 Dec 14.

    PMID:
    21163314
    [PubMed - indexed for MEDLINE]
    19.

    Characterisation of serpin polymers in vitro and in vivo.

    Belorgey D, Irving JA, Ekeowa UI, Freeke J, Roussel BD, Miranda E, Pérez J, Robinson CV, Marciniak SJ, Crowther DC, Michel CH, Lomas DA.

    Methods. 2011 Mar;53(3):255-66. doi: 10.1016/j.ymeth.2010.11.008. Epub 2010 Nov 27. Review.

    PMID:
    21115126
    [PubMed - indexed for MEDLINE]
    20.

    Two latent and two hyperstable polymeric forms of human neuroserpin.

    Ricagno S, Pezzullo M, Barbiroli A, Manno M, Levantino M, Santangelo MG, Bonomi F, Bolognesi M.

    Biophys J. 2010 Nov 17;99(10):3402-11. doi: 10.1016/j.bpj.2010.09.021.

    PMID:
    21081089
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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