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Results: 1 to 20 of 136

1.

Snail recruits Ring1B to mediate transcriptional repression and cell migration in pancreatic cancer cells.

Chen J, Xu H, Zou X, Wang J, Zhu Y, Chen H, Shen B, Deng X, Zhou A, Chin YE, Rauscher FJ 3rd, Peng C, Hou Z.

Cancer Res. 2014 Aug 15;74(16):4353-63. doi: 10.1158/0008-5472.CAN-14-0181. Epub 2014 Jun 5.

PMID:
24903147
[PubMed - in process]
2.

LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase.

Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, Carolin AS, Speicher DW, Skordalakes E, Huang Q, Dedhar S, Borden KL, Rauscher FJ 3rd.

Cancer Res. 2014 Mar 1;74(5):1390-403. doi: 10.1158/0008-5472.CAN-13-1275.

PMID:
24590809
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MAS promoter regulation: a role for Sry and tyrosine nitration of the KRAB domain of ZNF274 as a feedback mechanism.

Prokop JW, Rauscher FJ 3rd, Peng H, Liu Y, Araujo FC, Watanabe I, Reis FM, Milsted A.

Clin Sci (Lond). 2014 May;126(10):727-38. doi: 10.1042/CS20130385.

PMID:
24128372
[PubMed - indexed for MEDLINE]
4.

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes.

Fredericks WJ, Sepulveda J, Lai P, Tomaszewski JE, Lin MF, McGarvey T, Rauscher FJ 3rd, Malkowicz SB.

Oncotarget. 2013 Jul;4(7):1075-92.

PMID:
23919967
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Retraction: Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program.

Negorev DG, Vladimirova OV, Kossenkov AV, Demarest RM, Showe MK, Rauscher FJ 3rd, Showe LC, Nikonova EV, Capobianco AJ.

Cancer Res. 2013 Aug 1;73(15):4960-1. doi: 10.1158/0008-5472.CAN-13-1715. No abstract available.

PMID:
23907639
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ectopic expression of the TERE1 (UBIAD1) protein inhibits growth of renal clear cell carcinoma cells: altered metabolic phenotype associated with reactive oxygen species, nitric oxide and SXR target genes involved in cholesterol and lipid metabolism.

Fredericks WJ, Yin H, Lal P, Puthiyaveettil R, Malkowicz SB, Fredericks NJ, Tomaszewski J, Rauscher FJ 3rd, Malkowicz SB.

Int J Oncol. 2013 Aug;43(2):638-52. doi: 10.3892/ijo.2013.1985. Epub 2013 Jun 12.

PMID:
23759948
[PubMed - indexed for MEDLINE]
7.

A method for in silico identification of SNAIL/SLUG DNA binding potentials to the E-box sequence using molecular dynamics and evolutionary conserved amino acids.

Prokop JW, Liu Y, Milsted A, Peng H, Rauscher FJ 3rd.

J Mol Model. 2013 Sep;19(9):3463-9. doi: 10.1007/s00894-013-1876-y. Epub 2013 May 25.

PMID:
23708613
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The TERE1 protein interacts with mitochondrial TBL2: regulation of trans-membrane potential, ROS/RNS and SXR target genes.

Fredericks WJ, McGarvey T, Wang H, Zheng Y, Fredericks NJ, Yin H, Wang LP, Hsiao W, Lee R, Weiss JS, Nickerson ML, Kruth HS, Rauscher FJ 3rd, Malkowicz SB.

J Cell Biochem. 2013 Sep;114(9):2170-87. doi: 10.1002/jcb.24567.

PMID:
23564352
[PubMed - indexed for MEDLINE]
9.

Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature.

Wang T, Ge Y, Xiao M, Lopez-Coral A, Azuma R, Somasundaram R, Zhang G, Wei Z, Xu X, Rauscher FJ 3rd, Herlyn M, Kaufman RE.

Pigment Cell Melanoma Res. 2012 Jul;25(4):493-505. doi: 10.1111/j.1755-148X.2012.01005.x.

PMID:
22498258
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation.

White D, Rafalska-Metcalf IU, Ivanov AV, Corsinotti A, Peng H, Lee SC, Trono D, Janicki SM, Rauscher FJ 3rd.

Mol Cancer Res. 2012 Mar;10(3):401-14. doi: 10.1158/1541-7786.MCR-11-0134. Epub 2011 Dec 28.

PMID:
22205726
[PubMed - indexed for MEDLINE]
Free Article
11.

Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.

Liang Q, Deng H, Li X, Wu X, Tang Q, Chang TH, Peng H, Rauscher FJ 3rd, Ozato K, Zhu F.

J Immunol. 2011 Nov 1;187(9):4754-63. doi: 10.4049/jimmunol.1101704. Epub 2011 Sep 21.

PMID:
21940674
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Functional analysis of KAP1 genomic recruitment.

Iyengar S, Ivanov AV, Jin VX, Rauscher FJ 3rd, Farnham PJ.

Mol Cell Biol. 2011 May;31(9):1833-47. doi: 10.1128/MCB.01331-10. Epub 2011 Feb 22.

PMID:
21343339
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis.

Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ 3rd, Schultz DC, McMahon SB.

J Biol Chem. 2011 Feb 11;286(6):4264-70. doi: 10.1074/jbc.M110.184663. Epub 2010 Dec 9.

PMID:
21148320
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program.

Negorev DG, Vladimirova OV, Kossenkov AV, Nikonova EV, Demarest RM, Capobianco AJ, Showe MK, Rauscher FJ 3rd, Showe LC, Maul GG.

Cancer Res. 2010 Dec 1;70(23):9991-10001. doi: 10.1158/0008-5472.CAN-10-1483. Epub 2010 Nov 30. Retraction in: Negorev DG, Vladimirova OV, Kossenkov AV, Demarest RM, Showe MK, Rauscher FJ 3rd, Showe LC, Nikonova EV, Capobianco AJ. Cancer Res. 2013 Aug 1;73(15):4960-1.

PMID:
21118961
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.

Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky E, Milot E, Shi Y, Affar el B.

Mol Cell Biol. 2010 Nov;30(21):5071-85. doi: 10.1128/MCB.00396-10. Epub 2010 Aug 30.

PMID:
20805357
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

14-3-3 binding sites in the snail protein are essential for snail-mediated transcriptional repression and epithelial-mesenchymal differentiation.

Hou Z, Peng H, White DE, Wang P, Lieberman PM, Halazonetis T, Rauscher FJ 3rd.

Cancer Res. 2010 Jun 1;70(11):4385-93. doi: 10.1158/0008-5472.CAN-10-0070. Epub 2010 May 25. Erratum in: Cancer Res. 2010 Sep 1;70(17):7012-3.

PMID:
20501852
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling.

Hou Z, Peng H, White DE, Negorev DG, Maul GG, Feng Y, Longmore GD, Waxman S, Zelent A, Rauscher FJ 3rd.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2938-43. doi: 10.1073/pnas.0908656107. Epub 2010 Jan 26.

PMID:
20133701
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

Peng H, Ivanov AV, Oh HJ, Lau YF, Rauscher FJ 3rd.

J Biol Chem. 2009 Dec 18;284(51):35670-80. doi: 10.1074/jbc.M109.032086. Epub .

PMID:
19850934
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The year ahead.

Rauscher FJ 3rd.

Cancer Res. 2009 Jan 1;69(1):1. doi: 10.1158/0008-5472.CAN-69-1-ED. No abstract available.

PMID:
19117978
[PubMed - indexed for MEDLINE]
Free Article
20.

Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing.

Zeng L, Yap KL, Ivanov AV, Wang X, Mujtaba S, Plotnikova O, Rauscher FJ 3rd, Zhou MM.

Nat Struct Mol Biol. 2008 Jun;15(6):626-33. doi: 10.1038/nsmb.1416. Epub 2008 May 18.

PMID:
18488044
[PubMed - indexed for MEDLINE]
Free PMC Article

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