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Results: 1 to 20 of 35

Select item 232482921.

Proteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2.

Arlow T, Scott K, Wagenseller A, Gammie A.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):246-51. doi: 10.1073/pnas.1215510110. Epub 2012 Dec 17.

PMID:: 23248292; [PubMed - indexed for MEDLINE]

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Select item 232130892.

Multiple synchronous primary gynecologic malignancies in an MSH2 mutation carrier with endometriosis.

Shoni M, Parra-Herran CE, May T, Wright AA, Feltmate CM.

J Clin Oncol. 2013 Jan 20;31(3):e33-6. doi: 10.1200/JCO.2012.43.4274. Epub 2012 Dec 3. No abstract available.

PMID:: 23213089; [PubMed - indexed for MEDLINE]

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Select item 230845803.

Expression of p27, COX-2, MLH1, and MSH2 in young patients with colon carcinoma and correlation with morphologic findings.

Kenney B, Deng Y, Mitchell K.

Hum Pathol. 2013 Apr;44(4):591-7. doi: 10.1016/j.humpath.2012.07.003. Epub 2012 Oct 16.

PMID:: 23084580; [PubMed - indexed for MEDLINE]

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Select item 230455304.

Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair.

Hargreaves VV, Putnam CD, Kolodner RD.

J Biol Chem. 2012 Nov 30;287(49):41232-44. doi: 10.1074/jbc.M112.402495. Epub 2012 Oct 8.

PMID:: 23045530; [PubMed - indexed for MEDLINE]

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Select item 229388645.

Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions.

Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA.

Cell Rep. 2012 Aug 30;2(2):216-22. doi: 10.1016/j.celrep.2012.06.020. Epub 2012 Aug 2.

PMID:: 22938864; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 226692056.

Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia.

Abdul Murad NA, Othman Z, Khalid M, Abdul Razak Z, Hussain R, Nadesan S, Sagap I, Mohamed Rose I, Wan Ngah WZ, Jamal R.

Dig Dis Sci. 2012 Nov;57(11):2863-72. doi: 10.1007/s10620-012-2240-2. Epub 2012 Jun 6.

PMID:: 22669205; [PubMed - indexed for MEDLINE]

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Select item 225817037.

Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients.

Kantelinen J, Kansikas M, Candelin S, Hampel H, Smith B, Holm L, Kariola R, Nyström M.

Hum Mutat. 2012 Aug;33(8):1294-301. doi: 10.1002/humu.22119. Epub 2012 Jun 11.

PMID:: 22581703; [PubMed - indexed for MEDLINE]

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Select item 224531498.

Novel germline MLH1 and MSH2 mutations in Latvian Lynch syndrome families.

Bērziņa D, Irmejs A, Kalniete D, Borošenko V, Nakazawa-Miklaševiča M, Rībenieks K, Trofimovičs G, Gardovskis J, Miklaševičs E.

Exp Oncol. 2012;34(1):49-52.

PMID:: 22453149; [PubMed - indexed for MEDLINE]

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Select item 223868619.

Polymorphisms in MSH2 gene and risk of gastric cancer, and interactions with lifestyle factors in a Chinese population.

Wang D, Zhou J, Wang T, Li X, Li S, Chen S, Ma G, Li J, Zhang X.

Cancer Epidemiol. 2012 Jun;36(3):e171-6. doi: 10.1016/j.canep.2012.02.003. Epub 2012 Mar 2.

PMID:: 22386861; [PubMed - indexed for MEDLINE]

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Select item 2237164210.

Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients.

Zahary MN, Kaur G, Abu Hassan MR, Singh H, Naik VR, Ankathil R.

World J Gastroenterol. 2012 Feb 28;18(8):814-20. doi: 10.3748/wjg.v18.i8.814.

PMID:: 22371642; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2228333111.

High-resolution melting analyses for gene scanning of APC, MLH1, MSH2, and MSH6 associated with hereditary colorectal cancer.

Obul J, Itoga S, Abliz M, Sato K, Ishige T, Utsuno E, Matsushita K, Matsubara H, Nomura F.

Genet Test Mol Biomarkers. 2012 May;16(5):406-11. doi: 10.1089/gtmb.2011.0166. Epub 2012 Jan 27.

PMID:: 22283331; [PubMed - indexed for MEDLINE]

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Select item 2227766012.

Biochemical analysis of the human mismatch repair proteins hMutSα MSH2(G674A)-MSH6 and MSH2-MSH6(T1219D).

Geng H, Sakato M, DeRocco V, Yamane K, Du C, Erie DA, Hingorani M, Hsieh P.

J Biol Chem. 2012 Mar 23;287(13):9777-91. doi: 10.1074/jbc.M111.316919. Epub 2012 Jan 25.

PMID:: 22277660; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2226583913.

MSH2 promoter hypermethylation in circulating tumor DNA is a valuable predictor of disease-free survival for patients with esophageal squamous cell carcinoma.

Ling ZQ, Zhao Q, Zhou SL, Mao WM.

Eur J Surg Oncol. 2012 Apr;38(4):326-32. doi: 10.1016/j.ejso.2012.01.008. Epub 2012 Jan 23.

PMID:: 22265839; [PubMed - indexed for MEDLINE]

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Select item 2221900114.

The founder Ashkenazi Jewish mutations in the MSH2 and MSH6 genes in Israeli patients with gastric and pancreatic cancer.

Laitman Y, Herskovitz L, Golan T, Kaufman B, Paluch SS, Friedman E.

Fam Cancer. 2012 Jun;11(2):243-7. doi: 10.1007/s10689-011-9507-1.

PMID:: 22219001; [PubMed - indexed for MEDLINE]

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Select item 2217370315.

Esophageal cancer risk is associated with polymorphisms of DNA repair genes MSH2 and WRN in Chinese population.

Li T, Suo Q, He D, Du W, Yang M, Fan X, Liu J.

J Thorac Oncol. 2012 Feb;7(2):448-52. doi: 10.1097/JTO.0b013e31823c487a.

PMID:: 22173703; [PubMed - indexed for MEDLINE]

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Select item 2210261416.

A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.

Drost M, Zonneveld JB, van Hees S, Rasmussen LJ, Hofstra RM, de Wind N.

Hum Mutat. 2012 Mar;33(3):488-94. doi: 10.1002/humu.22000. Epub 2011 Dec 29.

PMID:: 22102614; [PubMed - indexed for MEDLINE]

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Select item 2208697417.

Pathogenicity of A600V variant in exon 12 of the MSH2 gene detected in a Japanese kindred with Lynch syndrome.

Miyakura Y, Sugano K, Nomizu T, Lefor A, Yasuda Y.

Jpn J Clin Oncol. 2012 Jan;42(1):78-82. doi: 10.1093/jjco/hyr162. Epub 2011 Nov 14.

PMID:: 22086974; [PubMed - indexed for MEDLINE]

Free Article

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Select item 2208630318.

Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors.

Rahner N, Brockschmidt FF, Steinke V, Kahl P, Becker T, Vasen HF, Wijnen JT, Tops CJ, Holinski-Feder E, Ligtenberg MJ, Spruijt L, Görgens H, Stemmler S, Kloor M, Dietmaier W; Dutch Cancer Genetics Group, Schumacher J, Nöthen MM, Propping P.

Fam Cancer. 2012 Mar;11(1):19-26. doi: 10.1007/s10689-011-9489-z.

PMID:: 22086303; [PubMed - indexed for MEDLINE]

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Select item 2206733419.

"Null pattern" of immunoreactivity in a Lynch syndrome-associated colon cancer due to germline MSH2 mutation and somatic MLH1 hypermethylation.

Hagen CE, Lefferts J, Hornick JL, Srivastava A.

Am J Surg Pathol. 2011 Dec;35(12):1902-5. doi: 10.1097/PAS.0b013e318237c6ab.

PMID:: 22067334; [PubMed - indexed for MEDLINE]

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Select item 2201107520.

Impact of colonoscopic screening in male and female Lynch syndrome carriers with an MSH2 mutation.

Stuckless S, Green JS, Morgenstern M, Kennedy C, Green RC, Woods MO, Fitzgerald W, Cox J, Parfrey PS.

Clin Genet. 2012 Nov;82(5):439-45. doi: 10.1111/j.1399-0004.2011.01802.x. Epub 2011 Nov 15.

PMID:: 22011075; [PubMed - indexed for MEDLINE]

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8 free full-text articles in PubMed Central

Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions. [Cell Rep. 2012]
Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions.
Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA. Cell Rep. 2012 Aug 30; 2(2):216-22. Epub 2012 Aug 2.
Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients. [World J Gastroenterol. 2012]
Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients.
Zahary MN, Kaur G, Abu Hassan MR, Singh H, Naik VR, Ankathil R. World J Gastroenterol. 2012 Feb 28; 18(8):814-20.
Biochemical analysis of the human mismatch repair proteins hMutSα MSH2(G674A)-MSH6 and MSH2-MSH6(T1219D). [J Biol Chem. 2012]
Biochemical analysis of the human mismatch repair proteins hMutSα MSH2(G674A)-MSH6 and MSH2-MSH6(T1219D).
Geng H, Sakato M, DeRocco V, Yamane K, Du C, Erie DA, Hingorani M, Hsieh P. J Biol Chem. 2012 Mar 23; 287(13):9777-91. Epub 2012 Jan 25.

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