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Interaction of ApoA-IV with NR4A1 and NR1D1 Represses G6Pase and PEPCK Transcription: Nuclear Receptor-Mediated Downregulation of Hepatic Gluconeogenesis in Mice and a Human Hepatocyte Cell Line.

Li X, Xu M, Wang F, Ji Y, DavidsoN WS, Li Z, Tso P.

PLoS One. 2015 Nov 10;10(11):e0142098. doi: 10.1371/journal.pone.0142098. eCollection 2015.


G6PC3 Deficiency: Primary Immune Deficiency Beyond Just Neutropenia.

Kiykim A, Baris S, Karakoc-Aydiner E, Ozen AO, Ogulur I, Bozkurt S, Ataizi CC, Boztug K, Barlan IB.

J Pediatr Hematol Oncol. 2015 Nov;37(8):616-22. doi: 10.1097/MPH.0000000000000441.


The Metabolic Regulator Histone Deacetylase 9 Contributes to Glucose Homeostasis Abnormality Induced by Hepatitis C Virus Infection.

Chen J, Wang N, Dong M, Guo M, Zhao Y, Zhuo Z, Zhang C, Chi X, Pan Y, Jiang J, Tang H, Niu J, Yang D, Li Z, Han X, Wang Q, Chen X.

Diabetes. 2015 Dec;64(12):4088-98. doi: 10.2337/db15-0197. Epub 2015 Sep 29.


PRDX1 is involved in palmitate induced insulin resistance via regulating the activity of p38MAPK in HepG2 cells.

Tang Z, Xia N, Yuan X, Zhu X, Xu G, Cui S, Zhang T, Zhang W, Zhao Y, Wang S, Shi B.

Biochem Biophys Res Commun. 2015 Oct 2;465(4):670-7. doi: 10.1016/j.bbrc.2015.08.008. Epub 2015 Aug 21.


In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis.

Connolly F, Rae MT, Späth K, Boswell L, McNeilly AS, Duncan WC.

PLoS One. 2015 Jul 6;10(7):e0132113. doi: 10.1371/journal.pone.0132113. eCollection 2015.


The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells.

Jeon JY, Lee H, Park J, Lee M, Park SW, Kim JS, Lee M, Cho B, Kim K, Choi AM, Kim CK, Yun M.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):440-6. doi: 10.1016/j.bbrc.2015.05.103. Epub 2015 May 30.


PCBP2 regulates hepatic insulin sensitivity via HIF-1α and STAT3 pathway in HepG2 cells.

Xia N, Tang Z, Wang C, Xu G, Nie X, Zhang W, Zhao Y, Wang S, Zhu X, Cui S.

Biochem Biophys Res Commun. 2015 Jul 17-24;463(1-2):116-22. doi: 10.1016/j.bbrc.2015.04.150. Epub 2015 May 19.


Genetic and molecular analyses reveal G6PC as a key element connecting glucose metabolism and cell cycle control in ovarian cancer.

Guo T, Chen T, Gu C, Li B, Xu C.

Tumour Biol. 2015 Sep;36(10):7649-58. doi: 10.1007/s13277-015-3463-6. Epub 2015 Apr 30.


Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway.

Jhuang HJ, Hsu WH, Lin KT, Hsu SL, Wang FS, Chou CK, Lee KH, Tsou AP, Lai JM, Yeh SF, Huang CY.

Oncotarget. 2015 Apr 10;6(10):7788-803.


Application of whole exome sequencing to a rare inherited metabolic disease with neurological and gastrointestinal manifestations: a congenital disorder of glycosylation mimicking glycogen storage disease.

Choi R, Woo HI, Choe BH, Park S, Yoon Y, Ki CS, Lee SY, Kim JW, Song J, Kim DS, Kwon S, Park HD.

Clin Chim Acta. 2015 Apr 15;444:50-3. doi: 10.1016/j.cca.2015.02.008. Epub 2015 Feb 11.


Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas.

Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH.

Mol Oncol. 2015 Apr;9(4):758-71. doi: 10.1016/j.molonc.2014.12.002. Epub 2014 Dec 19.


Hepatic lentiviral gene transfer prevents the long-term onset of hepatic tumours of glycogen storage disease type 1a in mice.

Clar J, Mutel E, Gri B, Creneguy A, Stefanutti A, Gaillard S, Ferry N, Beuf O, Mithieux G, Nguyen TH, Rajas F.

Hum Mol Genet. 2015 Apr 15;24(8):2287-96. doi: 10.1093/hmg/ddu746. Epub 2015 Jan 5.


Functional analysis of mutations in a severe congenital neutropenia syndrome caused by glucose-6-phosphatase-β deficiency.

Lin SR, Pan CJ, Mansfield BC, Chou JY.

Mol Genet Metab. 2015 Jan;114(1):41-5. doi: 10.1016/j.ymgme.2014.11.012. Epub 2014 Nov 26.


Discovery of a phosphodiesterase 9A inhibitor as a potential hypoglycemic agent.

Shao YX, Huang M, Cui W, Feng LJ, Wu Y, Cai Y, Li Z, Zhu X, Liu P, Wan Y, Ke H, Luo HB.

J Med Chem. 2014 Dec 26;57(24):10304-13. doi: 10.1021/jm500836h. Epub 2014 Dec 8.


Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.

Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP.

Clin Exp Immunol. 2015 Mar;179(3):398-413. doi: 10.1111/cei.12465.


Type I glycogen storage diseases: disorders of the glucose-6-phosphatase/glucose-6-phosphate transporter complexes.

Chou JY, Jun HS, Mansfield BC.

J Inherit Metab Dis. 2015 May;38(3):511-9. doi: 10.1007/s10545-014-9772-x. Epub 2014 Oct 7. Review.


Intralipid decreases apolipoprotein M levels and insulin sensitivity in rats.

Zheng L, Feng Y, Shi Y, Zhang J, Mu Q, Qin L, Berggren-Söderlund M, Nilsson-Ehle P, Zhang X, Luo G, Xu N.

PLoS One. 2014 Aug 21;9(8):e105681. doi: 10.1371/journal.pone.0105681. eCollection 2014.


The flavones apigenin and luteolin induce FOXO1 translocation but inhibit gluconeogenic and lipogenic gene expression in human cells.

Bumke-Vogt C, Osterhoff MA, Borchert A, Guzman-Perez V, Sarem Z, Birkenfeld AL, Bähr V, Pfeiffer AF.

PLoS One. 2014 Aug 19;9(8):e104321. doi: 10.1371/journal.pone.0104321. eCollection 2014.


Meta-analysis of genome-wide association study of homeostasis model assessment β cell function and insulin resistance in an East Asian population and the European results.

Hong KW, Chung M, Cho SB.

Mol Genet Genomics. 2014 Dec;289(6):1247-55. doi: 10.1007/s00438-014-0885-6. Epub 2014 Jul 30.

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