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    Results: 17

    1.

    p63RhoGEF-mediated formation of a single polarized lamellipodium is required for chemotactic migration in breast carcinoma cells.

    Hayashi A, Hiatari R, Tsuji T, Ohashi K, Mizuno K.

    FEBS Lett. 2013 Mar 18;587(6):698-705. doi: 10.1016/j.febslet.2013.01.043. Epub 2013 Feb 1.

    PMID:
    23380069
    [PubMed - indexed for MEDLINE]
    2.

    A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.

    Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL.

    Clin Cancer Res. 2012 Sep 15;18(18):5099-109. Epub 2012 Jul 27.

    PMID:
    22843789
    [PubMed - indexed for MEDLINE]
    3.

    Two novel missense mutations in FGD4/FRABIN cause Charcot-Marie-Tooth type 4H (CMT4H).

    Baudot C, Esteve C, Castro C, Poitelon Y, Mas C, Hamadouche T, El-Rajab M, Lévy N, Megarbané A, Delague V.

    J Peripher Nerv Syst. 2012 Jun;17(2):141-6. doi: 10.1111/j.1529-8027.2012.00405.x.

    PMID:
    22734899
    [PubMed - indexed for MEDLINE]
    4.

    Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells.

    Liu HP, Chen CC, Wu CC, Huang YC, Liu SC, Liang Y, Chang KP, Chang YS.

    PLoS Pathog. 2012;8(5):e1002690. doi: 10.1371/journal.ppat.1002690. Epub 2012 May 10.

    PMID:
    22589722
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study.

    Langevin SM, Koestler DC, Christensen BC, Butler RA, Wiencke JK, Nelson HH, Houseman EA, Marsit CJ, Kelsey KT.

    Epigenetics. 2012 Mar;7(3):291-9. doi: 10.4161/epi.7.3.19134.

    PMID:
    22430805
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Genome-wide association study of copy number variants suggests LTBP1 and FGD4 are important for alcohol drinking.

    Pei YF, Zhang L, Yang TL, Han Y, Hai R, Ran S, Tian Q, Shen H, Li J, Zhu XZ, Luo X, Deng HW.

    PLoS One. 2012;7(1):e30860. doi: 10.1371/journal.pone.0030860. Epub 2012 Jan 25.

    PMID:
    22295116
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Genetic spectrum of hereditary neuropathies with onset in the first year of life.

    Baets J, Deconinck T, De Vriendt E, Zimoń M, Yperzeele L, Van Hoorenbeeck K, Peeters K, Spiegel R, Parman Y, Ceulemans B, Van Bogaert P, Pou-Serradell A, Bernert G, Dinopoulos A, Auer-Grumbach M, Sallinen SL, Fabrizi GM, Pauly F, Van den Bergh P, Bilir B, Battaloglu E, Madrid RE, Kabzińska D, Kochanski A, Topaloglu H, Miller G, Jordanova A, Timmerman V, De Jonghe P.

    Brain. 2011 Sep;134(Pt 9):2664-76. doi: 10.1093/brain/awr184. Epub 2011 Aug 11.

    PMID:
    21840889
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Differential protein expression by dendritic cells from atopic and non-atopic individuals after stimulation by the major house dust mite allergen Der p 1.

    Horlock C, Shakib F, Jones NS, Sewell HF, Ghaemmaghami AM.

    Int Arch Allergy Immunol. 2009;150(3):237-51. doi: 10.1159/000222676. Epub 2009 Jun 4.

    PMID:
    19494521
    [PubMed - indexed for MEDLINE]
    9.

    Further evidence that mutations in FGD4/frabin cause Charcot-Marie-Tooth disease type 4H.

    Fabrizi GM, Taioli F, Cavallaro T, Ferrari S, Bertolasi L, Casarotto M, Rizzuto N, Deconinck T, Timmerman V, De Jonghe P.

    Neurology. 2009 Mar 31;72(13):1160-4. doi: 10.1212/01.wnl.0000345373.58618.b6.

    PMID:
    19332693
    [PubMed - indexed for MEDLINE]
    10.

    A novel Frabin (FGD4) nonsense mutation p.R275X associated with phenotypic variability in CMT4H.

    Houlden H, Hammans S, Katifi H, Reilly MM.

    Neurology. 2009 Feb 17;72(7):617-20. doi: 10.1212/01.wnl.0000342463.35089.cc.

    PMID:
    19221294
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Histopathological findings in hereditary motor and sensory neuropathy of axonal type with onset in early childhood associated with mitofusin 2 mutations.

    Vallat JM, Ouvrier RA, Pollard JD, Magdelaine C, Zhu D, Nicholson GA, Grew S, Ryan MM, Funalot B.

    J Neuropathol Exp Neurol. 2008 Nov;67(11):1097-102. doi: 10.1097/NEN.0b013e31818b6cbc.

    PMID:
    18957892
    [PubMed - indexed for MEDLINE]
    12.

    Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane.

    Nakanishi H, Takai Y.

    J Cell Mol Med. 2008 Aug;12(4):1169-76. doi: 10.1111/j.1582-4934.2008.00345.x. Epub 2008 Apr 9. Review.

    PMID:
    18410521
    [PubMed - indexed for MEDLINE]
    13.

    Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4.

    Stendel C, Roos A, Deconinck T, Pereira J, Castagner F, Niemann A, Kirschner J, Korinthenberg R, Ketelsen UP, Battaloglu E, Parman Y, Nicholson G, Ouvrier R, Seeger J, De Jonghe P, Weis J, Krüttgen A, Rudnik-Schöneborn S, Bergmann C, Suter U, Zerres K, Timmerman V, Relvas JB, Senderek J.

    Am J Hum Genet. 2007 Jul;81(1):158-64. Epub 2007 May 24.

    PMID:
    17564972
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H.

    Delague V, Jacquier A, Hamadouche T, Poitelon Y, Baudot C, Boccaccio I, Chouery E, Chaouch M, Kassouri N, Jabbour R, Grid D, Mégarbané A, Haase G, Lévy N.

    Am J Hum Genet. 2007 Jul;81(1):1-16. Epub 2007 May 15.

    PMID:
    17564959
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Homozygosity mapping of autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy (CMT4H) to a novel locus on chromosome 12p11.21-q13.11.

    De Sandre-Giovannoli A, Delague V, Hamadouche T, Chaouch M, Krahn M, Boccaccio I, Maisonobe T, Chouery E, Jabbour R, Atweh S, Grid D, Mégarbané A, Lévy N.

    J Med Genet. 2005 Mar;42(3):260-5. No abstract available.

    PMID:
    15744041
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42.

    Chen XM, Splinter PL, Tietz PS, Huang BQ, Billadeau DD, LaRusso NF.

    J Biol Chem. 2004 Jul 23;279(30):31671-8. Epub 2004 May 7.

    PMID:
    15133042
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells.

    Nakahara H, Otani T, Sasaki T, Miura Y, Takai Y, Kogo M.

    Genes Cells. 2003 Dec;8(12):1019-27.

    PMID:
    14750956
    [PubMed - indexed for MEDLINE]

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