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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 61
1994 2
1998 2
1999 4
2000 270
2001 3
2002 441
2003 6
2004 14
2005 3
2006 24
2007 2
2008 2
2009 3
2010 1
2011 1
2012 96
2014 4
2015 4
2016 13
2017 77
2018 853
2019 20830
2020 37271
2021 43050
2022 42665
2023 41107
2024 13673

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175,935 results

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Page 1
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth.
de Visser KE, Joyce JA. de Visser KE, et al. Cancer Cell. 2023 Mar 13;41(3):374-403. doi: 10.1016/j.ccell.2023.02.016. Cancer Cell. 2023. PMID: 36917948 Free article. Review.
Cancers represent complex ecosystems comprising tumor cells and a multitude of non-cancerous cells, embedded in an altered extracellular matrix. ...These host cells were once considered bystanders of tumorigenesis but are now known to play critical roles in the path
Cancers represent complex ecosystems comprising tumor cells and a multitude of non-cancerous cells, embedded in an altered ext
Cancer and stem cells.
Yin W, Wang J, Jiang L, James Kang Y. Yin W, et al. Exp Biol Med (Maywood). 2021 Aug;246(16):1791-1801. doi: 10.1177/15353702211005390. Epub 2021 Apr 5. Exp Biol Med (Maywood). 2021. PMID: 33820469 Free PMC article. Review.
A tremendous effort has been made to understand the origin of cancer cells, the formation of cancerous tissues, and the mechanism by which they spread and relapse, but the disease still remains mysterious. ...Based on current understandings of the properties of ( …
A tremendous effort has been made to understand the origin of cancer cells, the formation of cancerous tissues, and the mechan …
Targeting STAT3 in Cancer Immunotherapy.
Zou S, Tong Q, Liu B, Huang W, Tian Y, Fu X. Zou S, et al. Mol Cancer. 2020 Sep 24;19(1):145. doi: 10.1186/s12943-020-01258-7. Mol Cancer. 2020. PMID: 32972405 Free PMC article. Review.
As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune response. STAT3 is broadly hyperactivated both in cancer and non-cancerous cells within the …
As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central i …
Notch signaling pathway: architecture, disease, and therapeutics.
Zhou B, Lin W, Long Y, Yang Y, Zhang H, Wu K, Chu Q. Zhou B, et al. Signal Transduct Target Ther. 2022 Mar 24;7(1):95. doi: 10.1038/s41392-022-00934-y. Signal Transduct Target Ther. 2022. PMID: 35332121 Free PMC article. Review.
In terms of cancers, NOTCH signaling can both promote and inhibit tumor development in various types of cancer. ...Additionally, NOTCH mutation has been proposed as a predictive biomarker for immune checkpoint blockade therapy in many cancers. Collectively, t …
In terms of cancers, NOTCH signaling can both promote and inhibit tumor development in various types of cancer. ...Additionall …
Current cancer burden in China: epidemiology, etiology, and prevention.
Maomao C, He L, Dianqin S, Siyi H, Xinxin Y, Fan Y, Shaoli Z, Changfa X, Lin L, Ji P, Wanqing C. Maomao C, et al. Cancer Biol Med. 2022 Aug 30;19(8):1121-38. doi: 10.20892/j.issn.2095-3941.2022.0231. Cancer Biol Med. 2022. PMID: 36069534 Free PMC article. Review.
Lung (657,000; 27.2%), liver (336,400, 13.9%), and stomach (288,500; 12.0%) cancers are the 3 most deadly cancers in the general population. The 5-year survival rate for cancer has dramatically increased in recent decades. ...The Chinese government has made u …
Lung (657,000; 27.2%), liver (336,400, 13.9%), and stomach (288,500; 12.0%) cancers are the 3 most deadly cancers in the gener …
Epigenetics as a mediator of plasticity in cancer.
Feinberg AP, Levchenko A. Feinberg AP, et al. Science. 2023 Feb 10;379(6632):eaaw3835. doi: 10.1126/science.aaw3835. Epub 2023 Feb 10. Science. 2023. PMID: 36758093 Free PMC article. Review.
In this Review, we discuss modern approaches to epigenetic and gene regulation landscapes and the associated ideas of entropy and attractor states, illustrating how their definitions are both more precise and relevant to understanding cancer etiology and the plasticity of …
In this Review, we discuss modern approaches to epigenetic and gene regulation landscapes and the associated ideas of entropy and attractor …
Colorectal Cancer in Inflammatory Bowel Disease: Mechanisms and Management.
Shah SC, Itzkowitz SH. Shah SC, et al. Gastroenterology. 2022 Mar;162(3):715-730.e3. doi: 10.1053/j.gastro.2021.10.035. Epub 2021 Oct 29. Gastroenterology. 2022. PMID: 34757143 Free PMC article. Review.
Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic inflammation is the driver of neoplastic progression, resulting in dysplastic precursor lesions that may …
Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC), despite decreases in CRC …
Analysis of status and countermeasures of cancer incidence and mortality in China.
Wu C, Li M, Meng H, Liu Y, Niu W, Zhou Y, Zhao R, Duan Y, Zeng Z, Li X, Li G, Xiong W, Zhou M. Wu C, et al. Sci China Life Sci. 2019 May;62(5):640-647. doi: 10.1007/s11427-018-9461-5. Epub 2019 Mar 12. Sci China Life Sci. 2019. PMID: 30900169 Review.
On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. ...This review ana …
On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of ca
Unexpected guests in the tumor microenvironment: microbiome in cancer.
Wong-Rolle A, Wei HK, Zhao C, Jin C. Wong-Rolle A, et al. Protein Cell. 2021 May;12(5):426-435. doi: 10.1007/s13238-020-00813-8. Epub 2020 Dec 9. Protein Cell. 2021. PMID: 33296049 Free PMC article. Review.
Emerging evidence has revealed that the local microbiota make up an important part of the tumor microenvironment across many types of cancer, especially in cancers arising from mucosal sites, including the lung, skin and gastrointestinal tract. ...This review aims t …
Emerging evidence has revealed that the local microbiota make up an important part of the tumor microenvironment across many types of can
How the ageing microenvironment influences tumour progression.
Fane M, Weeraratna AT. Fane M, et al. Nat Rev Cancer. 2020 Feb;20(2):89-106. doi: 10.1038/s41568-019-0222-9. Epub 2019 Dec 13. Nat Rev Cancer. 2020. PMID: 31836838 Free PMC article. Review.
Most cancers arise in individuals over the age of 60. As the world population is living longer and reaching older ages, cancer is becoming a substantial public health problem. ...We also discuss the contribution of these changes to responses to cancer therapy …
Most cancers arise in individuals over the age of 60. As the world population is living longer and reaching older ages, cancer
175,935 results
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