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Items: 1 to 20 of 286

1.

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, Virgin HW, Mazmanian SK.

Science. 2016 May 27;352(6289):1116-20. doi: 10.1126/science.aad9948. Epub 2016 May 5.

PMID:
27230380
2.

Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis.

Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies FM, Rubinsztein DC.

Nat Commun. 2016 Feb 3;7:10533. doi: 10.1038/ncomms10533.

3.

Association of ATG5 Gene Polymorphisms With Behçet's Disease and ATG10 Gene Polymorphisms With VKH Syndrome in a Chinese Han Population.

Zheng M, Yu H, Zhang L, Li H, Liu Y, Kijlstra A, Yang P.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8280-7. doi: 10.1167/iovs.15-18035.

PMID:
26747760
4.

Pathogenic aspects and therapeutic avenues of intestinal fibrosis in Crohn's disease.

Zorzi F, Calabrese E, Monteleone G.

Clin Sci (Lond). 2015 Dec;129(12):1107-13. doi: 10.1042/CS20150472. Review.

PMID:
26494636
5.

Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy.

Vacchelli E, Semeraro M, Enot DP, Chaba K, Poirier Colame V, Dartigues P, Perier A, Villa I, Rusakiewicz S, Gronnier C, Goéré D, Mariette C, Zitvogel L, Kroemer G.

Oncotarget. 2015 Aug 28;6(25):20840-50.

6.

Genetic variants of the autophagy pathway as prognostic indicators for prostate cancer.

Huang CY, Huang SP, Lin VC, Yu CC, Chang TY, Lu TL, Chiang HC, Bao BY.

Sci Rep. 2015 Sep 14;5:14045. doi: 10.1038/srep14045.

7.

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard TR, Vahedi H, Sood A, Sung JJ, Malekzadeh R, Westra HJ, Yamazaki K, Yang SK; International Multiple Sclerosis Genetics Consortium; International IBD Genetics Consortium, Barrett JC, Franke A, Alizadeh BZ, Parkes M, B K T, Daly MJ, Kubo M, Anderson CA, Weersma RK.

Nat Genet. 2015 Sep;47(9):979-86. doi: 10.1038/ng.3359. Epub 2015 Jul 20.

8.

MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury.

Wang IK, Sun KT, Tsai TH, Chen CW, Chang SS, Yu TM, Yen TH, Lin FY, Huang CC, Li CY.

Life Sci. 2015 Sep 1;136:133-41. doi: 10.1016/j.lfs.2015.07.002. Epub 2015 Jul 10.

PMID:
26165754
9.

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.

Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ.

Cell Rep. 2015 Jun 30;11(12):1905-18. doi: 10.1016/j.celrep.2015.05.045. Epub 2015 Jun 18.

10.

ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.

Song H, Pu J, Wang L, Wu L, Xiao J, Liu Q, Chen J, Zhang M, Liu Y, Ni M, Mo J, Zheng Y, Wan D, Cai X, Cao Y, Xiao W, Ye L, Tu E, Lin Z, Wen J, Lu X, He J, Peng Y, Su J, Zhang H, Zhao Y, Lin M, Zhang Z.

Autophagy. 2015;11(8):1308-25. doi: 10.1080/15548627.2015.1060386.

PMID:
26083323
11.

Genetic determinants of quantitative traits associated with cardiovascular disease risk.

Smolková B, Bonassi S, Buociková V, Dušinská M, Horská A, Kuba D, Džupinková Z, Rašlová K, Gašparovič J, Slíž I, Ceppi M, Vohnout B, Wsólová L, Volkovová K.

Mutat Res. 2015 Aug;778:18-25. doi: 10.1016/j.mrfmmm.2015.05.005. Epub 2015 May 15.

PMID:
26043189
12.

Polymorphisms in autophagy genes are associated with paget disease of bone.

Usategui-Martín R, García-Aparicio J, Corral-Gudino L, Calero-Paniagua I, Del Pino-Montes J, González Sarmiento R.

PLoS One. 2015 Jun 1;10(6):e0128984. doi: 10.1371/journal.pone.0128984. eCollection 2015.

13.

TRAF3IP3, a novel autophagy up-regulated gene, is involved in marginal zone B lymphocyte development and survival.

Peng S, Wang K, Gu Y, Chen Y, Nan X, Xing J, Cui Q, Chen Y, Ge Q, Zhao H.

Clin Exp Immunol. 2015 Oct;182(1):57-68. doi: 10.1111/cei.12658. Epub 2015 Jul 7.

PMID:
26011558
14.

Genetic Polymorphisms in Autophagy-Associated Genes in Korean Children With Early-Onset Crohn Disease.

Na SY, Park SS, Seo JK.

J Pediatr Gastroenterol Nutr. 2015 Sep;61(3):285-91. doi: 10.1097/MPG.0000000000000796. Erratum in: J Pediatr Gastroenterol Nutr. 2016 Feb;62(2):357.

PMID:
25944217
15.

ATG16L1: A multifunctional susceptibility factor in Crohn disease.

Salem M, Ammitzboell M, Nys K, Seidelin JB, Nielsen OH.

Autophagy. 2015 Apr 3;11(4):585-94. doi: 10.1080/15548627.2015.1017187. Review.

16.

IRGM governs the core autophagy machinery to conduct antimicrobial defense.

Chauhan S, Mandell MA, Deretic V.

Mol Cell. 2015 May 7;58(3):507-21. doi: 10.1016/j.molcel.2015.03.020. Epub 2015 Apr 16.

17.

CNTNAP3 associated ATG16L1 expression and Crohn's disease.

Qiao YQ, Huang ML, Zheng Q, Wang TR, Xu AT, Cao Y, Zhao D, Ran ZH, Shen J.

Mediators Inflamm. 2015;2015:404185. doi: 10.1155/2015/404185. Epub 2015 Mar 26.

18.

Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms.

Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM.

PLoS One. 2015 Apr 8;10(4):e0123057. doi: 10.1371/journal.pone.0123057. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128048. Mills, Ian [corrected to Mills, Ian G].

19.

Defective macrophage handling of Escherichia coli in Crohn's disease.

Elliott TR, Hudspith BN, Rayment NB, Prescott NJ, Petrovska L, Hermon-Taylor J, Brostoff J, Boussioutas A, Mathew CG, Sanderson JD.

J Gastroenterol Hepatol. 2015 Aug;30(8):1265-74. doi: 10.1111/jgh.12955.

PMID:
25809337
20.

Monocyte-derived macrophages from Crohn's disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile.

Vazeille E, Buisson A, Bringer MA, Goutte M, Ouchchane L, Hugot JP, de Vallée A, Barnich N, Bommelaer G, Darfeuille-Michaud A.

J Crohns Colitis. 2015 May;9(5):410-20. doi: 10.1093/ecco-jcc/jjv053. Epub 2015 Mar 24.

PMID:
25805890
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