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    Results: 1 to 20 of 165

    1.

    TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3.

    Boada-Romero E, Letek M, Fleischer A, Pallauf K, Ramón-Barros C, Pimentel-Muiños FX.

    EMBO J. 2013 Feb 20;32(4):566-82. doi: 10.1038/emboj.2013.8. Epub 2013 Feb 1.

    PMID:
    23376921
    [PubMed - indexed for MEDLINE]
    2.

    Inflammatory bowel disease: dysfunction of autophagy?

    Scharl M, Rogler G.

    Dig Dis. 2012;30 Suppl 3:12-9. doi: 10.1159/000342588. Epub 2013 Jan 3. Review.

    PMID:
    23295687
    [PubMed - indexed for MEDLINE]
    3.

    The VMP1-Beclin 1 interaction regulates autophagy induction.

    Molejon MI, Ropolo A, Re AL, Boggio V, Vaccaro MI.

    Sci Rep. 2013;3:1055. doi: 10.1038/srep01055. Epub 2013 Jan 11.

    PMID:
    23316280
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.

    Ver Heul AM, Fowler CA, Ramaswamy S, Piper RC.

    J Biol Chem. 2013 Mar 8;288(10):6890-902. doi: 10.1074/jbc.M112.413781. Epub 2013 Jan 8.

    PMID:
    23300079
    [PubMed - indexed for MEDLINE]
    5.

    Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

    Gammoh N, Florey O, Overholtzer M, Jiang X.

    Nat Struct Mol Biol. 2013 Feb;20(2):144-9. doi: 10.1038/nsmb.2475. Epub 2012 Dec 23.

    PMID:
    23262492
    [PubMed - indexed for MEDLINE]
    6.

    Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.

    Otomo C, Metlagel Z, Takaesu G, Otomo T.

    Nat Struct Mol Biol. 2013 Jan;20(1):59-66. doi: 10.1038/nsmb.2431. Epub 2012 Dec 2.

    PMID:
    23202584
    [PubMed - indexed for MEDLINE]
    7.

    Trees Assembling Mann-Whitney approach for detecting genome-wide joint association among low-marginal-effect loci.

    Wei C, Schaid DJ, Lu Q.

    Genet Epidemiol. 2013 Jan;37(1):84-91. doi: 10.1002/gepi.21693. Epub 2012 Nov 7.

    PMID:
    23135745
    [PubMed - indexed for MEDLINE]
    8.

    Promises, delivery, and challenges of inflammatory bowel disease risk gene discovery.

    Brant SR.

    Clin Gastroenterol Hepatol. 2013 Jan;11(1):22-6. doi: 10.1016/j.cgh.2012.11.001. Epub 2012 Nov 3. Review.

    PMID:
    23131344
    [PubMed - indexed for MEDLINE]
    9.

    SNP-SNP interactions discovered by logic regression explain Crohn's disease genetics.

    Dinu I, Mahasirimongkol S, Liu Q, Yanai H, Sharaf Eldin N, Kreiter E, Wu X, Jabbari S, Tokunaga K, Yasui Y.

    PLoS One. 2012;7(10):e43035. doi: 10.1371/journal.pone.0043035. Epub 2012 Oct 12.

    PMID:
    23071489
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Interactions between intestinal microbiota and innate immune system in pediatric inflammatory bowel disease.

    Cucchiara S, Stronati L, Aloi M.

    J Clin Gastroenterol. 2012 Oct;46 Suppl:S64-6. doi: 10.1097/MCG.0b013e31826a857f.

    PMID:
    22955361
    [PubMed - indexed for MEDLINE]
    11.

    Crohn disease ATG16L1 polymorphism increases susceptibility to infection with Helicobacter pylori in humans.

    Raju D, Hussey S, Jones NL.

    Autophagy. 2012 Sep;8(9):1387-8. doi: 10.4161/auto.21007. Epub 2012 Aug 13.

    PMID:
    22885761
    [PubMed - indexed for MEDLINE]
    12.

    Lys05: a new lysosomal autophagy inhibitor.

    Amaravadi RK, Winkler JD.

    Autophagy. 2012 Sep;8(9):1383-4. doi: 10.4161/auto.20958. Epub 2012 Aug 10.

    PMID:
    22878685
    [PubMed - indexed for MEDLINE]
    13.

    Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility.

    Van Limbergen J, Kabakchiev B, Stempak JM, Schumm P, Xu W, Henderson P, Girardin S, Griffiths AM, Philpott D, Silverberg M.

    Gut. 2013 Feb;62(2):331-3. doi: 10.1136/gutjnl-2012-303165. Epub 2012 Jul 24. No abstract available.

    PMID:
    22833393
    [PubMed - indexed for MEDLINE]
    14.

    Evidence from genetics for a role of autophagy and innate immunity in IBD pathogenesis.

    Parkes M.

    Dig Dis. 2012;30(4):330-3. doi: 10.1159/000338119. Epub 2012 Jul 12. Review.

    PMID:
    22796792
    [PubMed - indexed for MEDLINE]
    15.

    The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

    Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP.

    Immunity. 2012 Jun 29;36(6):933-46. doi: 10.1016/j.immuni.2012.03.025.

    PMID:
    22749352
    [PubMed - indexed for MEDLINE]
    16.

    Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity.

    Ishibashi K, Uemura T, Waguri S, Fukuda M.

    Mol Biol Cell. 2012 Aug;23(16):3193-202. doi: 10.1091/mbc.E12-01-0010. Epub 2012 Jun 27.

    PMID:
    22740627
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.

    Li E, Hamm CM, Gulati AS, Sartor RB, Chen H, Wu X, Zhang T, Rohlf FJ, Zhu W, Gu C, Robertson CE, Pace NR, Boedeker EC, Harpaz N, Yuan J, Weinstock GM, Sodergren E, Frank DN.

    PLoS One. 2012;7(6):e26284. doi: 10.1371/journal.pone.0026284. Epub 2012 Jun 13.

    PMID:
    22719818
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo.

    Wang C, Mendonsa GR, Symington JW, Zhang Q, Cadwell K, Virgin HW, Mysorekar IU.

    Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):11008-13. doi: 10.1073/pnas.1203952109. Epub 2012 Jun 19.

    PMID:
    22715292
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Caspase activation regulates the extracellular export of autophagic vacuoles.

    Sirois I, Groleau J, Pallet N, Brassard N, Hamelin K, Londono I, Pshezhetsky AV, Bendayan M, Hébert MJ.

    Autophagy. 2012 Jun;8(6):927-37. doi: 10.4161/auto.19768. Epub 2012 Jun 1.

    PMID:
    22692030
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.

    Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP.

    Cell Cycle. 2012 Jun 15;11(12):2285-302. doi: 10.4161/cc.20718. Epub 2012 Jun 15.

    PMID:
    22684298
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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