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Results: 1 to 20 of 51

1.

Effects of DNAzymes and siRNA targeting AKT1 on the growth of human T leukemic cells.

Zhang M, Zhao H, Shi XZ, Wu J, Fu Q, Shi W.

Clin Lab. 2014;60(1):1-8.

PMID:
24600969
[PubMed - indexed for MEDLINE]
2.

The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells.

Zhou W, Fu XQ, Zhang LL, Zhang J, Huang X, Lu XH, Shen L, Liu BN, Liu J, Luo HS, Yu JP, Yu HG.

Cell Death Dis. 2013 Oct 10;4:e847. doi: 10.1038/cddis.2013.375.

PMID:
24113181
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.

Li X, Li Z, Zhou W, Xing X, Huang L, Tian L, Chen J, Chen C, Ma X, Yang Z.

Cell Death Dis. 2013 Sep 12;4:e803-9. doi: 10.1038/cddis.2013.331.

PMID:
24030155
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Neurogenesis and increase in differentiated neural cell survival via phosphorylation of Akt1 after fluoxetine treatment of stem cells.

Rahmani A, Kheradmand D, Keyhanvar P, Shoae-Hassani A, Darbandi-Azar A.

Biomed Res Int. 2013;2013:582526. doi: 10.1155/2013/582526. Epub 2013 Aug 18.

PMID:
24024202
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Haploinsufficiency of akt1 prolongs the lifespan of mice.

Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Ishii N, Minamino T.

PLoS One. 2013 Jul 30;8(7):e69178. doi: 10.1371/journal.pone.0069178. Print 2013.

PMID:
23935948
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

AKT1 gene mutation levels are correlated with the type of dermatologic lesions in patients with Proteus syndrome.

Lindhurst MJ, Wang JA, Bloomhardt HM, Witkowski AM, Singh LN, Bick DP, Gambello MJ, Powell CM, Lee CC, Darling TN, Biesecker LG.

J Invest Dermatol. 2014 Feb;134(2):543-6. doi: 10.1038/jid.2013.312. Epub 2013 Jul 24. No abstract available.

PMID:
23884311
[PubMed - indexed for MEDLINE]
7.

A signal transduction pathway from TGF-β1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma.

Qu X, Shen L, Zheng Y, Cui Y, Feng Z, Liu F, Liu J.

J Invest Dermatol. 2014 Jan;134(1):159-67. doi: 10.1038/jid.2013.281. Epub 2013 Jun 21.

PMID:
23792459
[PubMed - indexed for MEDLINE]
8.

The PI3K/Akt1 pathway enhances steady-state levels of FANCL.

Dao KH, Rotelli MD, Brown BR, Yates JE, Rantala J, Tognon C, Tyner JW, Druker BJ, Bagby GC.

Mol Biol Cell. 2013 Aug;24(16):2582-92. doi: 10.1091/mbc.E13-03-0144. Epub 2013 Jun 19.

PMID:
23783032
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain.

Kumar A, Purohit R.

PLoS One. 2013 May 31;8(5):e64364. doi: 10.1371/journal.pone.0064364. Print 2013.

PMID:
23741320
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A detailed immunohistochemical analysis of the PI3K/AKT/mTOR pathway in lung cancer: correlation with PIK3CA, AKT1, K-RAS or PTEN mutational status and clinicopathological features.

Trigka EA, Levidou G, Saetta AA, Chatziandreou I, Tomos P, Thalassinos N, Anastasiou N, Spartalis E, Kavantzas N, Patsouris E, Korkolopoulou P.

Oncol Rep. 2013 Aug;30(2):623-36. doi: 10.3892/or.2013.2512. Epub 2013 May 31.

PMID:
23728071
[PubMed - indexed for MEDLINE]
11.

Akt1 enhances CA916798 expression through mTOR pathway.

Wang YL, Zhu BJ, Qi ZZ, Wang HJ, Zhou XD.

PLoS One. 2013 May 8;8(5):e62327. doi: 10.1371/journal.pone.0062327. Print 2013.

PMID:
23667466
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetic variation in AKT1, PTEN and the 8q24 locus, and the risk of testicular germ cell tumor.

Andreassen KE, Kristiansen W, Karlsson R, Aschim EL, Dahl O, Fosså SD, Adami HO, Wiklund F, Haugen TB, Grotmol T.

Hum Reprod. 2013 Jul;28(7):1995-2002. doi: 10.1093/humrep/det127. Epub 2013 May 2.

PMID:
23639623
[PubMed - indexed for MEDLINE]
13.

Distinct and specific roles of AKT1 and AKT2 in androgen-sensitive and androgen-independent prostate cancer cells.

Cariaga-Martinez AE, López-Ruiz P, Nombela-Blanco MP, Motiño O, González-Corpas A, Rodriguez-Ubreva J, Lobo MV, Cortés MA, Colás B.

Cell Signal. 2013 Jul;25(7):1586-97. doi: 10.1016/j.cellsig.2013.03.019. Epub 2013 Apr 6.

PMID:
23567263
[PubMed - indexed for MEDLINE]
14.

AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation.

Long M, Hao M, Dong K, Shen J, Wang X, Lin F, Liu L, Wei J, Liang Y, Yang J, Gu F, Zhang H.

Cell Signal. 2013 Jun;25(6):1438-46. doi: 10.1016/j.cellsig.2013.03.001. Epub 2013 Mar 14.

PMID:
23499911
[PubMed - indexed for MEDLINE]
15.

Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medication.

Kumarasinghe N, Beveridge NJ, Gardiner E, Scott RJ, Yasawardene S, Perera A, Mendis J, Suriyakumara K, Schall U, Tooney PA.

Int J Neuropsychopharmacol. 2013 Aug;16(7):1483-503. doi: 10.1017/S1461145713000035. Epub 2013 Feb 27.

PMID:
23442539
[PubMed - indexed for MEDLINE]
16.

High-level somatic mosaicism of AKT1 c.49G>A mutation in skin scrapings from epidermal nevi enables non-invasive molecular diagnosis in patients with Proteus syndrome.

Wieland I, Tinschert S, Zenker M.

Am J Med Genet A. 2013 Apr;161A(4):889-91. doi: 10.1002/ajmg.a.35764. Epub 2013 Feb 22. No abstract available.

PMID:
23436452
[PubMed - indexed for MEDLINE]
17.

IL-17 induces expression of vascular cell adhesion molecule through signalling pathway of NF-κB, but not Akt1 and TAK1 in vascular smooth muscle cells.

Zhang H, Chen J, Liu X, Awar L, McMickle A, Bai F, Nagarajan S, Yu S.

Scand J Immunol. 2013 Apr;77(4):230-7. doi: 10.1111/sji.12030.

PMID:
23421430
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.

Clark VE, Erson-Omay EZ, Serin A, Yin J, Cotney J, Ozduman K, Avşar T, Li J, Murray PB, Henegariu O, Yilmaz S, Günel JM, Carrión-Grant G, Yilmaz B, Grady C, Tanrikulu B, Bakircioğlu M, Kaymakçalan H, Caglayan AO, Sencar L, Ceyhun E, Atik AF, Bayri Y, Bai H, Kolb LE, Hebert RM, Omay SB, Mishra-Gorur K, Choi M, Overton JD, Holland EC, Mane S, State MW, Bilgüvar K, Baehring JM, Gutin PH, Piepmeier JM, Vortmeyer A, Brennan CW, Pamir MN, Kiliç T, Lifton RP, Noonan JP, Yasuno K, Günel M.

Science. 2013 Mar 1;339(6123):1077-80. doi: 10.1126/science.1233009. Epub 2013 Jan 24.

PMID:
23348505
[PubMed - indexed for MEDLINE]
Free Article
19.

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.

Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, Beroukhim R.

Nat Genet. 2013 Mar;45(3):285-9. doi: 10.1038/ng.2526. Epub 2013 Jan 20.

PMID:
23334667
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Glioma is formed by active Akt1 alone and promoted by active Rac1 in transgenic zebrafish.

Jung IH, Leem GL, Jung DE, Kim MH, Kim EY, Kim SH, Park HC, Park SW.

Neuro Oncol. 2013 Mar;15(3):290-304. doi: 10.1093/neuonc/nos387. Epub 2013 Jan 16.

PMID:
23325864
[PubMed - indexed for MEDLINE]
Free PMC Article

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