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    Results: 1 to 20 of 46

    1.

    IL-17 induces expression of vascular cell adhesion molecule through signalling pathway of NF-κB, but not Akt1 and TAK1 in vascular smooth muscle cells.

    Zhang H, Chen J, Liu X, Awar L, McMickle A, Bai F, Nagarajan S, Yu S.

    Scand J Immunol. 2013 Apr;77(4):230-7. doi: 10.1111/sji.12030.

    PMID:
    23421430
    [PubMed - indexed for MEDLINE]
    2.

    Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.

    Clark VE, Erson-Omay EZ, Serin A, Yin J, Cotney J, Ozduman K, Avşar T, Li J, Murray PB, Henegariu O, Yilmaz S, Günel JM, Carrión-Grant G, Yilmaz B, Grady C, Tanrikulu B, Bakircioğlu M, Kaymakçalan H, Caglayan AO, Sencar L, Ceyhun E, Atik AF, Bayri Y, Bai H, Kolb LE, Hebert RM, Omay SB, Mishra-Gorur K, Choi M, Overton JD, Holland EC, Mane S, State MW, Bilgüvar K, Baehring JM, Gutin PH, Piepmeier JM, Vortmeyer A, Brennan CW, Pamir MN, Kiliç T, Lifton RP, Noonan JP, Yasuno K, Günel M.

    Science. 2013 Mar 1;339(6123):1077-80. doi: 10.1126/science.1233009. Epub 2013 Jan 24.

    PMID:
    23348505
    [PubMed - indexed for MEDLINE]
    3.

    Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes.

    Orloff MS, He X, Peterson C, Chen F, Chen JL, Mester JL, Eng C.

    Am J Hum Genet. 2013 Jan 10;92(1):76-80. doi: 10.1016/j.ajhg.2012.10.021. Epub 2012 Dec 13.

    PMID:
    23246288
    [PubMed - indexed for MEDLINE]
    4.

    mTORC2-PKBα/Akt1 Serine 473 phosphorylation axis is essential for regulation of FOXP3 Stability by chemokine CCL3 in psoriasis.

    Chen L, Wu J, Pier E, Zhao Y, Shen Z.

    J Invest Dermatol. 2013 Feb;133(2):418-28. doi: 10.1038/jid.2012.333. Epub 2012 Dec 6.

    PMID:
    23223135
    [PubMed - indexed for MEDLINE]
    5.

    Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression.

    Yang W, Ju JH, Lee KM, Nam K, Oh S, Shin I.

    Exp Cell Res. 2013 Feb 1;319(3):122-33. doi: 10.1016/j.yexcr.2012.11.014. Epub 2012 Nov 30.

    PMID:
    23200933
    [PubMed - indexed for MEDLINE]
    6.

    The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1.

    Cai N, Wang YD, Zheng PS.

    RNA. 2013 Jan;19(1):85-95. doi: 10.1261/rna.035295.112. Epub 2012 Nov 26.

    PMID:
    23185040
    [PubMed - indexed for MEDLINE]
    7.

    High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.

    Ney JT, Froehner S, Roesler A, Buettner R, Merkelbach-Bruse S.

    Arch Pathol Lab Med. 2012 Sep;136(9):983-92. doi: 10.5858/arpa.2011-0176-OA.

    PMID:
    22938585
    [PubMed - indexed for MEDLINE]
    8.

    FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway.

    Zhou J, Liao W, Yang J, Ma K, Li X, Wang Y, Wang D, Wang L, Zhang Y, Yin Y, Zhao Y, Zhu WG.

    Autophagy. 2012 Dec;8(12):1712-23. doi: 10.4161/auto.21830. Epub 2012 Aug 29.

    PMID:
    22931788
    [PubMed - indexed for MEDLINE]
    9.

    The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin.

    Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD.

    J Immunol. 2012 Sep 15;189(6):3104-11. doi: 10.4049/jimmunol.1201669. Epub 2012 Aug 17.

    PMID:
    22904301
    [PubMed - indexed for MEDLINE]
    10.

    Akt1 regulates phosphorylation and osteogenic activity of Dlx3.

    Choi YH, Choi HJ, Lee KY, Oh JW.

    Biochem Biophys Res Commun. 2012 Sep 7;425(4):800-5. doi: 10.1016/j.bbrc.2012.07.155. Epub 2012 Aug 2.

    PMID:
    22885182
    [PubMed - indexed for MEDLINE]
    11.

    Array CGH and PIK3CA/AKT1 mutations to drive patients to specific targeted agents: a clinical experience in 108 patients with metastatic breast cancer.

    Arnedos M, Scott V, Job B, De La Cruz J, Commo F, Mathieu MC, Wolp-Diniz R, Richon C, Campone M, Bachelot T, Dalenc F, Dessen P, Lacroix L, Lazar V, Soria JC, Delaloge S, Andre F.

    Eur J Cancer. 2012 Oct;48(15):2293-9. doi: 10.1016/j.ejca.2012.06.014. Epub 2012 Jul 26.

    PMID:
    22840369
    [PubMed - indexed for MEDLINE]
    12.

    Mutational analysis of PIK3CA, JAK2, BRAF, FOXL2, IDH1, AKT1 and EZH2 oncogenes in sarcomas.

    Je EM, An CH, Yoo NJ, Lee SH.

    APMIS. 2012 Aug;120(8):635-9. doi: 10.1111/j.1600-0463.2012.02878.x. Epub 2012 Mar 24.

    PMID:
    22779686
    [PubMed - indexed for MEDLINE]
    13.

    Mucinous breast carcinomas lack PIK3CA and AKT1 mutations.

    Kehr EL, Jorns JM, Ang D, Warrick A, Neff T, Degnin M, Lewis R, Beadling C, Corless CL, Troxell ML.

    Hum Pathol. 2012 Dec;43(12):2207-12. doi: 10.1016/j.humpath.2012.03.012. Epub 2012 Jun 15.

    PMID:
    22705004
    [PubMed - indexed for MEDLINE]
    14.

    AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia.

    Ekeowa-Anderson AL, Purdie KJ, Gibbon K, Byrne CR, Arbeit JM, Harwood CA, O'Shaughnessy RF.

    PLoS One. 2012;7(6):e38608. doi: 10.1371/journal.pone.0038608. Epub 2012 Jun 7.

    PMID:
    22685591
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells.

    Lo Ré AE, Fernández-Barrena MG, Almada LL, Mills LD, Elsawa SF, Lund G, Ropolo A, Molejon MI, Vaccaro MI, Fernandez-Zapico ME.

    J Biol Chem. 2012 Jul 20;287(30):25325-34. doi: 10.1074/jbc.M112.370809. Epub 2012 Apr 25.

    PMID:
    22535956
    [PubMed - indexed for MEDLINE]
    16.

    Effective connectivity of AKT1-mediated dopaminergic working memory networks and pharmacogenetics of anti-dopaminergic treatment.

    Tan HY, Chen AG, Kolachana B, Apud JA, Mattay VS, Callicott JH, Chen Q, Weinberger DR.

    Brain. 2012 May;135(Pt 5):1436-45. doi: 10.1093/brain/aws068. Epub 2012 Apr 23.

    PMID:
    22525159
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Differential function of Akt1 and Akt2 in human adipocytes.

    Fischer-Posovszky P, Tews D, Horenburg S, Debatin KM, Wabitsch M.

    Mol Cell Endocrinol. 2012 Jul 6;358(1):135-43. doi: 10.1016/j.mce.2012.03.018. Epub 2012 Mar 29.

    PMID:
    22480544
    [PubMed - indexed for MEDLINE]
    18.

    Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer.

    Juanpere N, Agell L, Lorenzo M, de Muga S, López-Vilaró L, Murillo R, Mojal S, Serrano S, Lorente JA, Lloreta J, Hernández S.

    Hum Pathol. 2012 Oct;43(10):1573-82. doi: 10.1016/j.humpath.2011.10.026. Epub 2012 Mar 12.

    PMID:
    22417847
    [PubMed - indexed for MEDLINE]
    19.

    Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients.

    van Beveren NJ, Buitendijk GH, Swagemakers S, Krab LC, Röder C, de Haan L, van der Spek P, Elgersma Y.

    PLoS One. 2012;7(2):e32618. doi: 10.1371/journal.pone.0032618. Epub 2012 Feb 29.

    PMID:
    22393424
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    RNAi knockdown of the Akt1 gene increases the chemosensitivity of gastric cancer cells to cisplatin both in vitro and in vivo.

    Zhou W, Fu XQ, Liu J, Yu HG.

    Regul Pept. 2012 Jun 10;176(1-3):13-21. doi: 10.1016/j.regpep.2012.02.003. Epub 2012 Mar 3.

    PMID:
    22387880
    [PubMed - indexed for MEDLINE]

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