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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1903 2
1906 2
1910 2
1911 2
1913 1
1917 1
1920 1
1921 5
1922 2
1923 1
1924 3
1925 2
1926 1
1927 1
1928 2
1929 2
1930 3
1931 2
1932 1
1933 5
1934 3
1935 4
1936 9
1937 3
1938 7
1939 7
1940 7
1941 8
1942 7
1943 6
1944 7
1945 17
1946 43
1947 79
1948 76
1949 83
1950 88
1951 99
1952 94
1953 89
1954 87
1955 133
1956 139
1957 153
1958 164
1959 190
1960 190
1961 254
1962 320
1963 448
1964 691
1965 573
1966 675
1967 828
1968 938
1969 1105
1970 1172
1971 1341
1972 1516
1973 1471
1974 1604
1975 2633
1976 2750
1977 2632
1978 2692
1979 2778
1980 3124
1981 3360
1982 3680
1983 4107
1984 4585
1985 4696
1986 4943
1987 5118
1988 4922
1989 5318
1990 5911
1991 5853
1992 5488
1993 5683
1994 5470
1995 5760
1996 5966
1997 5827
1998 5916
1999 6153
2000 6331
2001 6416
2002 6756
2003 7084
2004 7361
2005 8115
2006 8721
2007 9281
2008 9541
2009 9807
2010 10753
2011 11682
2012 12791
2013 13671
2014 14431
2015 15111
2016 16209
2017 16890
2018 18124
2019 20295
2020 23469
2021 26383
2022 29123
2023 28448
2024 10109

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436,133 results

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Page 1
The Role of Tryptophan Metabolites in Neuropsychiatric Disorders.
Davidson M, Rashidi N, Nurgali K, Apostolopoulos V. Davidson M, et al. Int J Mol Sci. 2022 Sep 1;23(17):9968. doi: 10.3390/ijms23179968. Int J Mol Sci. 2022. PMID: 36077360 Free PMC article. Review.
Tryptophan's metabolism process in the human body occurs using different pathways, including the kynurenine and serotonin pathways. ...In addition, tryptophan and its metabolites quantification following the neurotransmitters precursor are highlighted. …
Tryptophan's metabolism process in the human body occurs using different pathways, including the kynurenine and serotonin path …
LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice.
Wang LS, Zhang MD, Tao X, Zhou YF, Liu XM, Pan RL, Liao YH, Chang Q. Wang LS, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Apr 1;1112:24-32. doi: 10.1016/j.jchromb.2019.02.021. Epub 2019 Feb 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 30836315
l-Tryptophan (Trp) metabolites and related neurotransmitters play crucial roles in physiological functions, and their imbalances are implicated in the pathology of depression, Alzheimer's disease and other diseases. Measurement of Trp metabolites and related …
l-Tryptophan (Trp) metabolites and related neurotransmitters play crucial roles in physiological functions, and their imbalanc …
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Zhang FL, Chen XW, Wang YF, Hu Z, Zhang WJ, Zhou BW, Ci PF, Liu KX. Zhang FL, et al. J Transl Med. 2023 Apr 18;21(1):264. doi: 10.1186/s12967-023-04109-3. J Transl Med. 2023. PMID: 37072757 Free PMC article.
However, the relationship between Lactobacillus murinus (L. murinus)-derived tryptophan metabolites and intestinal ischemia/reperfusion (I/R) injury yet to be investigated. This study aimed to evaluate the role of L. murinus-derived tryptophan metabolites …
However, the relationship between Lactobacillus murinus (L. murinus)-derived tryptophan metabolites and intestinal ischemia/re …
Paroxysmal nocturnal hemoglobinuria (PNH) and primary p.Cys89Tyr mutation in CD59: Differences and similarities.
Mevorach D. Mevorach D. Mol Immunol. 2015 Sep;67(1):51-5. doi: 10.1016/j.molimm.2015.03.005. Epub 2015 Mar 26. Mol Immunol. 2015. PMID: 25818314 Review.
CD59 deficiency is a common finding in adult patients with paroxysmal nocturnal hemoglobinuria (PNH). In this condition, there is a clonal expansion of hematopoietic stem cells that have acquired a mutation in the PIGA gene (phosphatidylinositol glycan anchor …
CD59 deficiency is a common finding in adult patients with paroxysmal nocturnal hemoglobinuria (PNH). In this condition …
Congenital CD59 Deficiency.
Höchsmann B, Schrezenmeier H. Höchsmann B, et al. Hematol Oncol Clin North Am. 2015 Jun;29(3):495-507. doi: 10.1016/j.hoc.2015.01.006. Epub 2015 Apr 4. Hematol Oncol Clin North Am. 2015. PMID: 26043388 Review.
Chromatographic analysis of tryptophan metabolites.
Sadok I, Gamian A, Staniszewska MM. Sadok I, et al. J Sep Sci. 2017 Aug;40(15):3020-3045. doi: 10.1002/jssc.201700184. Epub 2017 Jun 26. J Sep Sci. 2017. PMID: 28590049 Free PMC article. Review.
The kynurenine pathway generates multiple tryptophan metabolites called collectively kynurenines and leads to formation of the enzyme cofactor nicotinamide adenine dinucleotide. ...Trace concentrations, interference of sample components, and instability of some t …
The kynurenine pathway generates multiple tryptophan metabolites called collectively kynurenines and leads to formation of the …
Hemolytic anemia.
Beutler E, Luzzatto L. Beutler E, et al. Semin Hematol. 1999 Oct;36(4 Suppl 7):38-47. Semin Hematol. 1999. PMID: 10595753 Review.
Hereditary disorders of the membrane generally cause shape changes, such as spherocytosis or ovalocytosis. Paroxysmal nocturnal hemoglobinuria is the result of an acquired (somatic) mutation of PIG-A, an X-linked component of the glycosylphosphatidylinositol …
Hereditary disorders of the membrane generally cause shape changes, such as spherocytosis or ovalocytosis. Paroxysmal nocturnal …
Acquired aplastic anemia.
Young NS. Young NS. Ann Intern Med. 2002 Apr 2;136(7):534-46. doi: 10.7326/0003-4819-136-7-200204020-00011. Ann Intern Med. 2002. PMID: 11926789 Free article. Review.
In patients with post-hepatitis aplastic anemia, antibodies to the known hepatitis viruses are absent; the unknown infectious agent may be more common in developing countries, where aplastic anemia occurs more frequently than it does in the West. The syndrome paroxysmal …
In patients with post-hepatitis aplastic anemia, antibodies to the known hepatitis viruses are absent; the unknown infectious agent may be m …
PAROXYSMAL nocturnal hemoglobinuria.
[No authors listed] [No authors listed] J Am Med Assoc. 1960 May 21;173:260-1. doi: 10.1001/jama.1960.03020210040011. J Am Med Assoc. 1960. PMID: 13857330 No abstract available.
Late-Stage Diversification of Tryptophan-Derived Biomolecules.
Gruß H, Sewald N. Gruß H, et al. Chemistry. 2020 Apr 24;26(24):5328-5340. doi: 10.1002/chem.201903756. Epub 2020 Mar 2. Chemistry. 2020. PMID: 31544296 Free PMC article. Review.
Pd-mediated reactions have emerged as a powerful tool for the site-selective and bioorthogonal late-stage diversification of amino acids, peptides and related compounds. Indole moieties of tryptophan derivatives are susceptible to C(2) H-activation, whereas halogenated aro …
Pd-mediated reactions have emerged as a powerful tool for the site-selective and bioorthogonal late-stage diversification of amino acids, pe …
436,133 results
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